Table of Contents

Relevance tier by entity

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Warnings

The variants reported in this gene in DLBCL failed QC

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 5.16
DLBCL Schmitz cohort 5.96
DLBCL Reddy cohort 3.30
DLBCL Chapuy cohort 2.14
MCL GAMBL genomes 1.90

Mutation pattern and selective pressure estimates

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Expression

All Mutations

Reddy_2072T Reddy_2076T Reddy_2142T Reddy_2163T Reddy_2217T Reddy_2219T Reddy_2220T Reddy_2228T Reddy_2261T Reddy_2262T Reddy_2298T Reddy_2303T Reddy_2461T Reddy_2464T Reddy_2479T Reddy_2539T Reddy_2562T Reddy_2567T Reddy_2581T Reddy_2624T Reddy_2626T Reddy_2639T Reddy_2643T Reddy_2706T Reddy_2773T Reddy_2775T Reddy_2785T Reddy_3401T Reddy_3412T Reddy_3438T Reddy_3462T Reddy_3467T Reddy_3486T Reddy_3495T Reddy_3496T Reddy_3504T Reddy_3505T Reddy_3528T Reddy_3560T Reddy_3596T Reddy_3609T Reddy_3610T Reddy_3616T Reddy_3638T Reddy_3640T Reddy_3644T Reddy_3647T Reddy_3652T Reddy_3655T Reddy_3660T Reddy_3663T Reddy_3679T Reddy_3686T Reddy_3687T Reddy_3707T Reddy_3708T Reddy_3715T Reddy_3725T Reddy_3726T Reddy_3732T Reddy_3740T Reddy_3764T Reddy_3811T Reddy_3832T Reddy_3886T Reddy_3898T Reddy_3921T Reddy_3923T Reddy_3935T Reddy_3939T Reddy_3941T Reddy_3944T Reddy_3967T Reddy_3979T Reddy_3980T Reddy_3986T Reddy_816T Reddy_823T

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References

1.
Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg ML, Nørgaard P, Pedersen M, Gang AO, Høgdall E, Heavican TB, Lone W, Iqbal J, Qin Q, Li G, Kim SY, Healy J, Richards KL, Fedoriw Y, Bernal-Mizrachi L, Koff JL, Staton AD, Flowers CR, Paltiel O, Goldschmidt N, Calaminici M, Clear A, Gribben J, Nguyen E, Czader MB, Ondrejka SL, Collie A, Hsi ED, Tse E, Au-Yeung RKH, Kwong YL, Srivastava G, Choi WWL, Evens AM, Pilichowska M, Sengar M, Reddy N, Li S, Chadburn A, Gordon LI, Jaffe ES, Levy S, Rempel R, Tzeng T, Happ LE, Dave T, Rajagopalan D, Datta J, Dunson DB, Dave SS. Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma. Cell. 2017 Oct;171(2):481–494.e15. PMCID: PMC5659841

Citing

If you use the information or data from this site, please cite

Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.

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