Gene Status First BL study Other lists
ARID1A Tier 1 Love et al DLBCL, FL, PMBL, MZL
BACH2 Tier 1 Grande et al
BCL6 Tier 1 Love et al DLBCL, FL
BCL7A Tier 1 Grande et al DLBCL, FL, PMBL, MZL
BMP7 Tier 1 Panea et al
CCND3 Tier 1 Richter et al DLBCL, FL, PMBL, MZL
CHD8 Tier 1 Grande et al PMBL
CREBBP Tier 1 Love et al DLBCL, FL, PMBL, MZL
DDX3X Tier 1 Schmitz et al DLBCL, FL, PMBL
EZH2 Tier 1 Love et al DLBCL, FL, PMBL, MZL
FBXO11 Tier 1 Richter et al DLBCL, MZL
FOXO1 Tier 1 Schmitz et al DLBCL, FL, PMBL, MZL
GNA13 Tier 1 Schmitz et al DLBCL, FL, PMBL
GNAI2 Tier 1 Grande et al DLBCL, FL
HIST1H1E Tier 1 Grande et al DLBCL, FL, PMBL
HNRNPU Tier 1 Panea et al DLBCL
ID3 Tier 1 Richter et al DLBCL, MZL
IGLL5 Tier 1 Panea et al DLBCL, FL, PMBL
KMT2D Tier 1 Grande et al DLBCL, FL, PMBL, MCL, MZL
MYC Tier 1 Johnston et al DLBCL, FL, PMBL, MZL
P2RY8 Tier 1 Muppidi et al DLBCL, FL, PMBL
PCBP1 Tier 1 Schmitz et al PMBL
PHF6 Tier 1 Thomas et al DLBCL
PTEN Tier 1 Love et al DLBCL
RFX7 Tier 1 Grande et al DLBCL
RHOA Tier 1 Richter et al DLBCL, FL, PMBL
SIN3A Tier 1 Grande et al DLBCL, PMBL, MZL
SMARCA4 Tier 1 Richter et al DLBCL, FL, PMBL, MCL
TCF3 Tier 1 Schmitz et al PMBL
TCL1A Tier 1 Grande et al DLBCL
TFAP4 Tier 1 Grande et al
TP53 Tier 1 Wilda et al DLBCL, FL, PMBL, MCL, MZL
USP7 Tier 1 Grande et al DLBCL
WNK1 Tier 1 Thomas et al DLBCL, MZL

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Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.

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