| Gene | Status | First BL study |
|---|---|---|
| ARID1A | Tier 1 | Love et al |
| BACH2 | Tier 1 | Grande et al |
| BCL6 | Tier 1 | Love et al |
| BCL7A | Tier 1 | Grande et al |
| BMP7 | Tier 1 | Panea et al |
| CCND3 | Tier 1 | Richter et al |
| CHD8 | Tier 1 | Grande et al |
| CREBBP | Tier 1 | Love et al |
| DDX3X | Tier 1 | Schmitz et al |
| EZH2 | Tier 1 | Love et al |
| FBXO11 | Tier 1 | Richter et al |
| FOXO1 | Tier 1 | Schmitz et al |
| GNA13 | Tier 1 | Schmitz et al |
| GNAI2 | Tier 1 | Grande et al |
| HIST1H1E | Tier 1 | Grande et al |
| HNRNPU | Tier 1 | Panea et al |
| ID3 | Tier 1 | Richter et al |
| IGLL5 | Tier 1 | Panea et al |
| KMT2D | Tier 1 | Grande et al |
| MYC | Tier 1 | Johnston et al |
| P2RY8 | Tier 1 | Muppidi et al |
| PCBP1 | Tier 1 | Schmitz et al |
| PHF6 | Tier 1 | Thomas et al |
| PTEN | Tier 1 | Love et al |
| RFX7 | Tier 1 | Grande et al |
| RHOA | Tier 1 | Richter et al |
| SIN3A | Tier 1 | Grande et al |
| SMARCA4 | Tier 1 | Richter et al |
| TCF3 | Tier 1 | Schmitz et al |
| TCL1A | Tier 1 | Grande et al |
| TFAP4 | Tier 1 | Grande et al |
| TP53 | Tier 1 | Wilda et al |
| USP7 | Tier 1 | Grande et al |
| WNK1 | Tier 1 | Thomas et al |
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
Disclaimer
The content in these pages has been populated, in part, by an automated process. Although we have scrutinized every page to ensure accuracy, errors will inevitably exist. If you find an error please report it as an issue and we will address it.
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
Adapt — remix, transform, and build upon the material for any purpose, even commercially. The licensor cannot revoke these freedoms as long as you follow the license terms.
