Table of Contents

Relevance tier by entity

Entity Tier Description
DLBCL 2 Role of DDX10 mutations in DLBCL requires confirmation

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 0.57
DLBCL Schmitz cohort 1.49
DLBCL Reddy cohort 0.80
DLBCL Chapuy cohort 1.71

Mutation pattern and selective pressure estimates

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Expression

All Mutations

Reddy_1016T Reddy_2112T Reddy_2166T Reddy_2205T Reddy_2226T Reddy_2247T Reddy_2261T Reddy_2548T Reddy_2605T Reddy_2644T Reddy_2728T Reddy_2772T Reddy_2878T Reddy_2881T Reddy_3408T Reddy_3448T Reddy_3511T Reddy_3513T Reddy_3558T Reddy_3624T Reddy_3682T Reddy_3816T Reddy_3840T Reddy_3916T Reddy_3937T Reddy_3972T Reddy_3982T

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References

1.
Zhang J, Grubor V, Love CL, Banerjee A, Richards KL, Mieczkowski PA, Dunphy C, Choi W, Au WY, Srivastava G, Lugar PL, Rizzieri DA, Lagoo AS, Bernal-Mizrachi L, Mann KP, Flowers C, Naresh K, Evens A, Gordon LI, Czader M, Gill JI, Hsi ED, Liu Q, Fan A, Walsh K, Jima D, Smith LL, Johnson AJ, Byrd JC, Luftig MA, Ni T, Zhu J, Chadburn A, Levy S, Dunson D, Dave SS. Genetic heterogeneity of diffuse large B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 2013;110:1398–1403. PMCID: PMC3557051

Citing

If you use the information or data from this site, please cite

Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.

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