DDX10
History
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timeline
title Publication timing
2013-01-01 : Zhang : DLBCL
2017-10-10 : Reddy : DLBCL
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | Relevance in DLBCL not firmly established1 |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 0.57 |
| DLBCL | Schmitz cohort | 1.49 |
| DLBCL | Reddy cohort | 0.80 |
| DLBCL | Chapuy cohort | 1.71 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 1.927 | 0.000 |
| DLBCL | No | No | 0.000 | 7.884 |
| FL | No | No | 0.000 | 0.000 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
DDX10 Expression
All Mutations
Reddy_1016T Reddy_2112T Reddy_2166T Reddy_2205T Reddy_2226T Reddy_2247T Reddy_2261T Reddy_2548T Reddy_2605T Reddy_2644T Reddy_2728T Reddy_2772T Reddy_2878T Reddy_2881T Reddy_3408T Reddy_3448T Reddy_3511T Reddy_3513T Reddy_3558T Reddy_3624T Reddy_3682T Reddy_3816T Reddy_3840T Reddy_3916T Reddy_3937T Reddy_3972T Reddy_3982T
References
1.
Zhang J, Grubor V, Love CL, Banerjee A,
Richards KL, Mieczkowski PA, Dunphy C, Choi W, Au WY, Srivastava G,
Lugar PL, Rizzieri DA, Lagoo AS, Bernal-Mizrachi L, Mann KP, Flowers C,
Naresh K, Evens A, Gordon LI, Czader M, Gill JI, Hsi ED, Liu Q, Fan A,
Walsh K, Jima D, Smith LL, Johnson AJ, Byrd JC, Luftig MA, Ni T, Zhu J,
Chadburn A, Levy S, Dunson D, Dave SS. Genetic heterogeneity of diffuse
large B-cell lymphoma. Proceedings of the
National Academy of Sciences of the United States of America.
2013;110:1398–1403. PMCID: PMC3557051