DDX10
The variants reported in this gene in DLBCL failed QC
History
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timeline
title Publication timing
2017-10-10 : Reddy : DLBCL
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
| 2-F | failed QC |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 0.57 |
| DLBCL | Schmitz cohort | 1.49 |
| DLBCL | Reddy cohort | 0.80 |
| DLBCL | Chapuy cohort | 1.71 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 1.927 | 0.000 |
| DLBCL | No | No | 0.000 | 7.884 |
| FL | No | No | 0.000 | 0.000 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
DDX10 Expression
All Mutations
Reddy_1016T Reddy_2112T Reddy_2166T Reddy_2205T Reddy_2226T Reddy_2247T Reddy_2261T Reddy_2548T Reddy_2605T Reddy_2644T Reddy_2728T Reddy_2772T Reddy_2878T Reddy_2881T Reddy_3408T Reddy_3448T Reddy_3511T Reddy_3513T Reddy_3558T Reddy_3624T Reddy_3682T Reddy_3816T Reddy_3840T Reddy_3916T Reddy_3937T Reddy_3972T Reddy_3982T
References
- Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg ML, Nørgaard P, Pedersen M, Gang AO, Høgdall E, Heavican TB, Lone W, Iqbal J, Qin Q, Li G, Kim SY, Healy J, Richards KL, Fedoriw Y, Bernal-Mizrachi L, Koff JL, Staton AD, Flowers CR, Paltiel O, Goldschmidt N, Calaminici M, Clear A, Gribben J, Nguyen E, Czader MB, Ondrejka SL, Collie A, Hsi ED, Tse E, Au-Yeung RKH, Kwong YL, Srivastava G, Choi WWL, Evens AM, Pilichowska M, Sengar M, Reddy N, Li S, Chadburn A, Gordon LI, Jaffe ES, Levy S, Rempel R, Tzeng T, Happ LE, Dave T, Rajagopalan D, Datta J, Dunson DB, Dave SS. Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma. Cell. 2017 Oct;171(2):481-494.e15.


