Origins and status of DLBCL genes
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Fan 2020, Tier 3, 72
Zhang 2013, Tier 1, 14
Zhang 2013, Tier 2, 9
Zhang 2013, Tier 3, 266
Chapuy 2018, Tier 1, 2
Chapuy 2018, Tier 2, 10
Chapuy 2018, Tier 3, 6
Schmitz 2018, Tier 1, 6
Schmitz 2018, Tier 2, 9
Morin 2011, Tier 1, 24
Morin 2011, Tier 2, 2
Morin 2016, Tier 1, 2
Pararajalingam 2020, Tier 2, 2
Pasqualucci 2011, Tier 1, 2
Hubschmann 2021, Tier 1, 3
Hubschmann 2021, Tier 2, 17
Hubschmann 2021, Tier 3, 3
Albuquerque 2017, Tier 1, 5
Albuquerque 2017, Tier 2, 5
Reddy 2017, Tier 1, 4
Reddy 2017, Tier 2, 23
Reddy 2017, Tier 3, 26
Morin 2013, Tier 1, 9
Morin 2013, Tier 2, 21
Morin 2013, Tier 3, 7
Pasqualucci 2011, Tier 1, 3
Pasqualucci 2011, Tier 2, 4
Arthur 2018, Tier 1, 5
Arthur 2018, Tier 2, 12
Lohr 2012, Tier 1, 18
Lohr 2012, Tier 2, 20
Pasqualucci 2001, Tier 1, 2
Pasqualucci 2001, Tier 2, 2
DLBCL genes, DLBCL-exome, 53
DLBCL-exome, Reddy 2017, 53
DLBCL genes, DLBCL-WGS, 37
DLBCL-WGS, Morin 2013, 37
DLBCL genes, DLBCL-exome, 7
DLBCL-exome, Pasqualucci 2011, 7
DLBCL genes, DLBCL-exome, 10
DLBCL-exome, Albuquerque 2017, 10
DLBCL genes, DLBCL-WGS, 17
DLBCL-WGS, Arthur 2018, 17
DLBCL genes, DLBCL-Sanger, 4
DLBCL-Sanger, Pasqualucci 2001, 4
DLBCL genes, DLBCL-exome, 38
DLBCL-exome, Lohr 2012, 38
DLBCL genes, DLBCL-exome, 289
DLBCL-exome, Zhang 2013, 289
DLBCL genes, DLBCL-exome, 18
DLBCL-exome, Chapuy 2018, 18
DLBCL genes, DLBCL-exome, 15
DLBCL-exome, Schmitz 2018, 15
DLBCL genes, DLBCL-exome, 72
DLBCL-exome, Fan 2020, 72
DLBCL genes, DLBCL-WGS, 23
DLBCL-WGS, Hubschmann 2021, 23
DLBCL genes, DLBCL-exome, 2
DLBCL-exome, Morin 2016, 2
DLBCL genes, DLBCL-RNA-seq/WGS, 26
DLBCL-RNA-seq/WGS, Morin 2011, 26
DLBCL genes, DLBCL-exome, 2
DLBCL-exome, Pasqualucci 2011, 2
DLBCL genes, DLBCL-WGS/exome, 2
DLBCL-WGS/exome, Pararajalingam 2020, 2
Tier 1 DLBCL genes
127 total
Tier 2 DLBCL genes
168 total
Tier 3 DLBCL genes
381 total
References
1.
Desch AK, Hartung K, Botzen A, Brobeil A,
Rummel M, Kurch L, Georgi T, Jox T, Bielack S, Burdach S, Classen CF,
Claviez A, Debatin KM, Ebinger M, Eggert A, Faber J, Flotho C, Frühwald
M, Graf N, Jorch N, Kontny U, Kramm C, Kulozik A, Kühr J, Sykora KW,
Metzler M, Müller HL, Nathrath M, Nüßlein T, Paulussen M, Pekrun A,
Reinhardt D, Reinhard H, Rössig C, Sauerbrey A, Schlegel PG, Schneider
DT, Scheurlen W, Schweigerer L, Simon T, Suttorp M, Vorwerk P, Schmitz
R, Kluge R, Mauz-Körholz C, Körholz D, Gattenlöhner S, Bräuninger A. Genotyping circulating
tumor DNA of pediatric Hodgkin lymphoma.
Leukemia. 2020 Jan;34(1):151–166.
2.
Zhang J, Grubor V, Love CL, Banerjee A,
Richards KL, Mieczkowski PA, Dunphy C, Choi W, Au WY, Srivastava G,
Lugar PL, Rizzieri DA, Lagoo AS, Bernal-Mizrachi L, Mann KP, Flowers C,
Naresh K, Evens A, Gordon LI, Czader M, Gill JI, Hsi ED, Liu Q, Fan A,
Walsh K, Jima D, Smith LL, Johnson AJ, Byrd JC, Luftig MA, Ni T, Zhu J,
Chadburn A, Levy S, Dunson D, Dave SS. Genetic heterogeneity of diffuse
large B-cell lymphoma. Proceedings of the
National Academy of Sciences of the United States of America.
2013;110:1398–1403. PMCID: PMC3557051
3.
Love
C, Sun Z, Jima D, Li G, Zhang J, Miles R, Richards KL, Dunphy CH, Choi
WWL, Srivastava G, Lugar PL, Rizzieri DA, Lagoo AS, Bernal-Mizrachi L,
Mann KP, Flowers CR, Naresh KN, Evens AM, Chadburn A, Gordon LI, Czader
MB, Gill JI, Hsi ED, Greenough A, Moffitt AB, McKinney M, Banerjee A,
Grubor V, Levy S, Dunson DB, Dave SS. The genetic landscape of mutations
in Burkitt lymphoma. Nat Genet. 2012 Dec;44(12):1321–1325.
PMCID: PMC3674561
4.
Reddy A, Zhang J, Davis NS, Moffitt AB, Love
CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg
ML, Nørgaard P, Pedersen M, Gang AO, Høgdall E, Heavican TB, Lone W,
Iqbal J, Qin Q, Li G, Kim SY, Healy J, Richards KL, Fedoriw Y,
Bernal-Mizrachi L, Koff JL, Staton AD, Flowers CR, Paltiel O,
Goldschmidt N, Calaminici M, Clear A, Gribben J, Nguyen E, Czader MB,
Ondrejka SL, Collie A, Hsi ED, Tse E, Au-Yeung RKH, Kwong YL, Srivastava
G, Choi WWL, Evens AM, Pilichowska M, Sengar M, Reddy N, Li S, Chadburn
A, Gordon LI, Jaffe ES, Levy S, Rempel R, Tzeng T, Happ LE, Dave T,
Rajagopalan D, Datta J, Dunson DB, Dave SS. Genetic and Functional
Drivers of Diffuse Large B Cell Lymphoma. Cell. 2017
Oct;171(2):481–494.e15. PMCID: PMC5659841
5.
Braggio E, Dogan A, Keats JJ, Chng WJ, Huang G,
Matthews JM, Maurer MJ, Law ME, Bosler DS, Barrett M, Lossos IS, Witzig
TE, Fonseca R. Genomic analysis of marginal zone and lymphoplasmacytic
lymphomas identified common and disease-specific abnormalities. Mod
Pathol. 2012 May;25(5):651–660. PMCID: PMC3341516
6.
Beà
S, Valdés-Mas R, Navarro A, Salaverria I, Martín-Garcia D, Jares P, Giné
E, Pinyol M, Royo C, Nadeu F, Conde L, Juan M, Clot G, Vizán P, Croce
LD, Puente DA, López-Guerra M, Moros A, Roue G, Aymerich M, Villamor N,
Colomo L, Martínez A, Valera A, Martín-Subero JI, Amador V, Hernández L,
Rozman M, Enjuanes A, Forcada P, Muntañola A, Hartmann EM, Calasanz MJ,
Rosenwald A, Ott G, Hernández-Rivas JM, Klapper W, Siebert R, Wiestner
A, Wilson WH, Colomer D, López-Guillermo A, López-Otín C, Puente XS,
Campo E. Landscape of
somatic mutations and clonal evolution in mantle cell lymphoma.
PNAS. 2013;110(45):18250–18255.
7.
Morin RD, Mendez-Lago M, Mungall AJ, Goya R,
Mungall KL, Corbett RD, Johnson NA, Severson TM, Chiu R, Field M,
Jackman S, Krzywinski M, Scott DW, Trinh DL, Tamura-Wells J, Li S, Firme
MR, Rogic S, Griffith M, Chan S, Yakovenko O, Meyer IM, Zhao EY, Smailus
D, Moksa M, Chittaranjan S, Rimsza L, Brooks-Wilson A, Spinelli JJ,
Ben-Neriah S, Meissner B, Woolcock B, Boyle M, McDonald H, Tam A, Zhao
Y, Delaney A, Zeng T, Tse K, Butterfield Y, Birol I, Holt R, Schein J,
Horsman DE, Moore R, Jones SJM, Connors JM, Hirst M, Gascoyne RD, Marra
MA. Frequent mutation of histone-modifying genes in
non-Hodgkin lymphoma. Nature. 2011 Jul
27;476(7360):298–303. PMCID: PMC3210554
8.
Pararajalingam P, Coyle KM, Arthur SE, Thomas
N, Alcaide M, Meissner B, Boyle M, Qureshi Q, Grande BM, Rushton C,
Slack GW, Mungall AJ, Tam CS, Agarwal R, Dawson SJ, Lenz G,
Balasubramanian S, Gascoyne RD, Steidl C, Connors J, Villa D, Audas TE,
Marra MA, Johnson NA, Scott DW, Morin RD. Coding and noncoding drivers
of mantle cell lymphoma identified through exome and genome sequencing.
Blood. 2020 Jul 30;136(5):572–584. PMCID: PMC7440974
9.
Tanaka S, Louie DC, Kant JA, Reed JC. Frequent incidence of
somatic mutations in translocated BCL2 oncogenes of
non-Hodgkin’s lymphomas. Blood. 1992 Jan
1;79(1):229–237.
10.
Grande BM, Gerhard DS, Jiang A, Griner NB,
Abramson JS, Alexander TB, Allen H, Ayers LW, Bethony JM, Bhatia K,
Bowen J, Casper C, Choi JK, Culibrk L, Davidsen TM, Dyer MA,
Gastier-Foster JM, Gesuwan P, Greiner TC, Gross TG, Hanf B, Harris NL,
He Y, Irvin JD, Jaffe ES, Jones SJM, Kerchan P, Knoetze N, Leal FE,
Lichtenberg TM, Ma Y, Martin JP, Martin MR, Mbulaiteye SM, Mullighan CG,
Mungall AJ, Namirembe C, Novik K, Noy A, Ogwang MD, Omoding A, Orem J,
Reynolds SJ, Rushton CK, Sandlund JT, Schmitz R, Taylor C, Wilson WH,
Wright GW, Zhao EY, Marra MA, Morin RD, Staudt LM. Genome-wide discovery
of somatic coding and noncoding mutations in pediatric endemic and
sporadic Burkitt lymphoma. Blood. 2019;133(12):1313–1324.
PMCID: PMC6428665
11.
Lenz G, Davis RE, Ngo VN, Lam L, George TC,
Wright GW, Dave SS, Zhao H, Xu W, Rosenwald A, Ott G, Müller-Hermelink
HK, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J,
Smeland EB, Fisher RI, Chan WC, Staudt LM. Oncogenic
CARD11 mutations in human diffuse large B cell
lymphoma. Science. 2008 Mar;319(5870):1676–1679.
12.
Wu
C, de Miranda NF, Chen L, Wasik AM, Mansouri L, Jurczak W, Galazka K,
Dlugosz-Danecka M, Machaczka M, Zhang H, Peng R, Morin RD, Rosenquist R,
Sander B, Pan-Hammarström Q. Genetic heterogeneity in primary and
relapsed mantle cell lymphomas: Impact of recurrent
CARD11 mutations. Oncotarget. 2016 Jun
21;7(25):38180–38190. PMCID: PMC5122381
13.
Jallades L, Baseggio L, Sujobert P, Huet S,
Chabane K, Callet-Bauchu E, Verney A, Hayette S, Desvignes JP, Salgado
D, Levy N, Béroud C, Felman P, Berger F, Magaud JP, Genestier L, Salles
G, Traverse-Glehen A. Exome sequencing identifies recurrent
BCOR alterations and the absence of KLF2,
TNFAIP3 and MYD88 mutations in splenic diffuse
red pulp small B-cell lymphoma.
Haematologica. 2017 Oct;102(10):1758–1766. PMCID: PMC5622860
14.
Panea R, Love C, Shingleton JR, Reddy A, Bailey
J, Moormann A, Otieno J, Ong’echa J, Oduor C, Schroêder K, Masalu N,
Chao N, Agajanian M, Major M, Fedoriw Y, Richards K, Rymkiewicz G, Miles
R, Alobeid B, Bhagat G, Flowers C, Ondrejka S, Hsi E, Choi W, Au-Yeung
R, Hartmann W, Lenz G, Meyerson H, Lin YY, Zhuang Y, Luftig M, Waldrop
A, Dave T, Thakkar D, Sahay H, Li G, Palus B, Seshadri V, Kim S,
Gascoyne R, Levy S, Mukhopadhyay M, Dunson D, Dave S. The whole genome
landscape of Burkitt lymphoma subtypes. Blood. 2019;
15.
Morin RD, Mungall K, Pleasance E, Mungall AJ,
Goya R, Huff RD, Scott DW, Ding J, Roth A, Chiu R, Corbett RD, Chan FC,
Mendez-Lago M, Trinh DL, Bolger-Munro M, Taylor G, Hadj Khodabakhshi A,
Ben-Neriah S, Pon J, Meissner B, Woolcock B, Farnoud N, Rogic S, Lim EL,
Johnson NA, Shah S, Jones S, Steidl C, Holt R, Birol I, Moore R, Connors
JM, Gascoyne RD, Marra MA. Mutational and structural analysis of diffuse
large B-cell lymphoma using whole-genome
sequencing. Blood. 2013 Aug 15;122(7):1256–1265. PMCID: PMC3744992
16.
Parry M, Rose-Zerilli MJJ, Gibson J, Ennis S,
Walewska R, Forster J, Parker H, Davis Z, Gardiner A, Collins A, Oscier
DG, Strefford JC. Whole exome sequencing identifies novel recurrently
mutated genes in patients with splenic marginal zone lymphoma. PLoS One.
2013;8(12):e83244. PMCID: PMC3862727
17.
Khodabakhshi AH, Morin RD, Fejes AP, Mungall
AJ, Mungall KL, Bolger-Munro M, Johnson NA, Connors JM, Gascoyne RD,
Marra MA, Birol I, Jones SJM. Recurrent targets of aberrant somatic
hypermutation in lymphoma. Oncotarget. 2012;3(11):1308–1319. PMCID: PMC3717795
18.
Schmitz R, Young RM, Ceribelli M, Jhavar S,
Xiao W, Zhang M, Wright G, Shaffer AL, Hodson DJ, Buras E, Liu X, Powell
J, Yang Y, Xu W, Zhao H, Kohlhammer H, Rosenwald A, Kluin P,
Müller-Hermelink HK, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E,
Jaffe ES, Delabie J, Smeland EB, Ogwang MD, Reynolds SJ, Fisher RI,
Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Pittaluga S,
Wilson W, Waldmann TA, Rowe M, Mbulaiteye SM, Rickinson AB, Staudt LM.
Burkitt lymphoma pathogenesis and therapeutic targets from structural
and functional genomics. Nature. 2012 Oct 4;490(7418):116–120. PMCID: PMC3609867
19.
Gomez F, Fisk B, McMichael JF, Mosior M, Foltz
JA, Skidmore ZL, Duncavage EJ, Miller CA, Abel H, Li YS, Russler-Germain
DA, Krysiak K, Watkins MP, Ramirez CA, Schmidt A, Martins Rodrigues F,
Trani L, Khanna A, Wagner JA, Fulton RS, Fronick CC, O’Laughlin MD,
Schappe T, Cashen AF, Mehta-Shah N, Kahl BS, Walker J, Bartlett NL,
Griffith M, Fehniger TA, Griffith OL. Ultra-Deep Sequencing
Reveals the Mutational Landscape of Classical
Hodgkin Lymphoma. Cancer Res Commun. 2023 Nov 15;3(11):2312–2330.
PMCID: PMC10648575
20.
Bohle V, Döring C, Hansmann M-L, Küppers R. Role of early B-cell factor 1 (EBF1) in
Hodgkin lymphoma. Leukemia. 2013 Mar;27(3):671–679.
21.
Thomas N, Dreval K, Gerhard DS, Hilton LK,
Abramson JS, Ambinder RF, Barta S, Bartlett NL, Bethony J, Bhatia K,
Bowen J, Bryan AC, Cesarman E, Casper C, Chadburn A, Cruz M, Dittmer DP,
Dyer MA, Farinha P, Gastier-Foster JM, Gerrie AS, Grande BM, Greiner T,
Griner NB, Gross TG, Harris NL, Irvin JD, Jaffe ES, Henry D, Huppi R,
Leal FE, Lee MS, Martin JP, Martin MR, Mbulaiteye SM, Mitsuyasu R,
Morris V, Mullighan CG, Mungall AJ, Mungall K, Mutyaba I, Nokta M,
Namirembe C, Noy A, Ogwang MD, Omoding A, Orem J, Ott G, Petrello H,
Pittaluga S, Phelan JD, Ramos JC, Ratner L, Reynolds SJ, Rubinstein PG,
Sissolak G, Slack G, Soudi S, Swerdlow SH, Traverse-Glehen A, Wilson WH,
Wong J, Yarchoan R, ZenKlusen JC, Marra MA, Staudt LM, Scott DW, Morin
RD. Genetic subgroups inform on pathobiology in adult and pediatric
Burkitt lymphoma. Blood. 2023 Feb 23;141(8):904–916. PMCID:
PMC10023728
22.
Scholl V, Stefanoff CG, Hassan R, Spector N,
Renault IZ. Mutations within the 5’
region of FAS/CD95 gene in nodal diffuse large
B-cell lymphoma. Leuk Lymphoma. 2007
May;48(5):957–963.
23.
Pasqualucci L, Trifonov V, Fabbri G, Ma J,
Rossi D, Chiarenza A, Wells VA, Grunn A, Messina M, Elliot O, Chan J,
Bhagat G, Chadburn A, Gaidano G, Mullighan CG, Rabadan R, Dalla-Favera
R. Analysis of the coding genome of diffuse large B-cell lymphoma. Nat Genet. 2011 Jul
31;43(9):830–837. PMCID: PMC3297422
24.
Arthur SE, Jiang A, Grande BM, Alcaide M,
Cojocaru R, Rushton CK, Mottok A, Hilton LK, Lat PK, Zhao EY, Culibrk L,
Ennishi D, Jessa S, Chong L, Thomas N, Pararajalingam P, Meissner B,
Boyle M, Davidson J, Bushell KR, Lai D, Farinha P, Slack GW, Morin GB,
Shah S, Sen D, Jones SJM, Mungall AJ, Gascoyne RD, Audas TE, Unrau P,
Marra MA, Connors JM, Steidl C, Scott DW, Morin RD. Genome-wide
discovery of somatic regulatory variants in diffuse large B-cell lymphoma. Nat Commun. 2018 Oct 1;9(1):4001.
PMCID: PMC6167379
25.
Zhou P, Blain AE, Newman AM, Zaka M, Chagaluka
G, Adlar FR, Offor UT, Broadbent C, Chaytor L, Whitehead A, Hall A,
O’Connor H, Van Noorden S, Lampert I, Bailey S, Molyneux E, Bacon CM,
Bomken S, Rand V. Sporadic and endemic Burkitt lymphoma
have frequent FOXO1 mutations but distinct hotspots in the
AKT recognition motif. Blood Adv. 2019 Jul
23;3(14):2118–2127. PMCID: PMC6650741
26.
Zhang J, Jima D, Moffitt AB, Liu Q, Czader M,
Hsi ED, Fedoriw Y, Dunphy CH, Richards KL, Gill JI, Sun Z, Love C,
Scotland P, Lock E, Levy S, Hsu DS, Dunson D, Dave SS. The genomic
landscape of mantle cell lymphoma is related to the epigenetically
determined chromatin state of normal B cells. Blood.
2014 May 8;123(19):2988–2996.
27.
Rushton CK, Arthur SE, Alcaide M, Cheung M,
Jiang A, Coyle KM, Cleary KLS, Thomas N, Hilton LK, Michaud N, Daigle S,
Davidson J, Bushell K, Yu S, Rys RN, Jain M, Shepherd L, Marra MA,
Kuruvilla J, Crump M, Mann K, Assouline S, Connors JM, Steidl C, Cragg
MS, Scott DW, Johnson NA, Morin RD. Genetic and evolutionary patterns of
treatment resistance in relapsed B-cell
lymphoma. Blood Adv. 2020 Jul 14;4(13):2886–2898. PMCID: PMC7362366
28.
Johnston JM, Carroll WL. C-myc hypermutation in
Burkitt’s lymphoma. Leuk Lymphoma. 1992
Dec;8(6):431–439.
29.
Lake A, Shield LA, Cordano P, Chui DTY, Osborne
J, Crae S, Wilson KS, Tosi S, Knight SJL, Gesk S, Siebert R, Hay RT,
Jarrett RF. Mutations of
NFKBIA, encoding IkappaB alpha, are a
recurrent finding in classical Hodgkin lymphoma but are not
a unifying feature of non-EBV-associated
cases. Int J Cancer. 2009 Sep 15;125(6):1334–1342.
30.
Morin RD, Assouline S, Alcaide M, Mohajeri A,
Johnston RL, Chong L, Grewal J, Yu S, Fornika D, Bushell K, Nielsen TH,
Petrogiannis-Haliotis T, Crump M, Tosikyan A, Grande BM, MacDonald D,
Rousseau C, Bayat M, Sesques P, Froment R, Albuquerque M, Monczak Y,
Oros KK, Greenwood C, Riazalhosseini Y, Arseneault M, Camlioglu E,
Constantin A, Pan-Hammarstrom Q, Peng R, Mann KK, Johnson NA. Genetic
Landscapes of Relapsed and Refractory
Diffuse Large B-Cell Lymphomas. Clin Cancer Res. 2016 May
1;22(9):2290–2300.
31.
Mansouri L, Noerenberg D, Young E, Mylonas E,
Abdulla M, Frick M, Asmar F, Ljungström V, Schneider M, Yoshida K,
Skaftason A, Pandzic T, Gonzalez B, Tasidou A, Waldhueter N,
Rivas-Delgado A, Angelopoulou M, Ziepert M, Arends CM, Couronné L, Lenze
D, Baldus CD, Bastard C, Okosun J, Fitzgibbon J, Dörken B, Drexler HG,
Roos-Weil D, Schmitt CA, Munch-Petersen HD, Zenz T, Hansmann ML,
Strefford JC, Enblad G, Bernard OA, Ralfkiaer E, Erlanson M,
Korkolopoulou P, Hultdin M, Papadaki T, Grønbæk K, Lopez-Guillermo A,
Ogawa S, Küppers R, Stamatopoulos K, Stavroyianni N, Kanellis G,
Rosenwald A, Campo E, Amini RM, Ott G, Vassilakopoulos TP, Hummel M,
Rosenquist R, Damm F. Frequent
NFKBIE deletions are associated with poor outcome in
primary mediastinal B-cell lymphoma.
Blood. 2016 Dec 8;128(23):2666–2670.
32.
Wilda M, Bruch J, Harder L, Rawer D, Reiter A,
Borkhardt A, Woessmann W. Inactivation of the ARF-MDM-2-p53 pathway in sporadic
Burkitt’s lymphoma in children. Leukemia. 2004
Mar;18(3):584–588.
33.
Mareschal S, Dubois S, Viailly PJ, Bertrand P,
Bohers E, Maingonnat C, Jaïs JP, Tesson B, Ruminy P, Peyrouze P,
Copie-Bergman C, Fest T, Jo Molina T, Haioun C, Salles G, Tilly H,
Lecroq T, Leroy K, Jardin F. Whole exome sequencing of
relapsed/refractory patients expands the repertoire of somatic mutations
in diffuse large B-cell lymphoma. Genes
Chromosomes Cancer. 2016 Mar;55(3):251–267.
34.
Ganapathi KA, Jobanputra V, Iwamoto F, Jain P,
Chen J, Cascione L, Nahum O, Levy B, Xie Y, Khattar P, Hoehn D, Bertoni
F, Murty VV, Pittaluga S, Jaffe ES, Alobeid B, Mansukhani MM, Bhagat G.
The genetic landscape
of dural marginal zone lymphomas. Oncotarget. Impact Journals; 2016
May 27;7(28):43052–43061.
35.
Shin SY, Lee ST, Kim HJ, Ki CS, Jung CW, Kim
JW, Kim SH. BRAF V600E and MAP2K1 mutations in
hairy cell leukemia and splenic marginal zone lymphoma cases. Ann Lab
Med. 2015 Mar;35(2):257–259. PMCID: PMC4330180
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