Origins of DLBCL genes

Tier 1, high-confidence DLBCL genes

125 total

Gene Summary First DLBCL study Other entities QC result
ACTB Tier 1 GE1, aSHM Lohr et al 2,3
ACTG1 Tier 1 GE4, aSHM Fan et al 5–7
ARID1A Tier 1 GE8, FE9 Zhang et al 3,10–12
ATM Tier 1 GE13, FE14 Reddy et al 15,16
B2M Tier 1 GE17, FE18 Morin et al 19,20
BCL10 Tier 1 GE17, FE21 Morin et al 7,22
BCL2 Tier 1 GE23, aSHM Tanaka et al 17,24,25
BCL6 Tier 1 GE17, FE26, aSHM Morin et al 2,11
BCL7A Tier 1 GE17, FE27, aSHM Morin et al 10,20,28
BIRC6 Tier 1 GE13 Reddy et al 25
BRAF Tier 1 GE29, FE30 Tiacci et al 11
BTG1 Tier 1 GE17, FE31, aSHM Morin et al 2,24,25
BTG2 Tier 1 GE17, aSHM Morin et al 2,11
BTK Tier 1 GE32, FE33 Albuquerque et al 10
CARD11 Tier 1 GE34, FE34 Lenz et al 17,35,36
CCND3 Tier 1 GE17, FE37 Morin et al 5,38,39
CD58 Tier 1 GE17, FE18 Morin et al 40
CD70 Tier 1 GE17, FE41 Morin et al 22
CD79B Tier 1 GE42, FE42 Davis et al 2,43
CD83 Tier 1 GE44, aSHM Morin et al 22,43,45
CDKN2A Tier 1 GE44, FE46 Morin et al 7,28
CIITA Tier 1 GE17, FE47, aSHM Morin et al 47
CREBBP Tier 1 GE48, FE48 Pasqualucci et al 11,45,49
CXCR4 Tier 1 GE50, FE51, aSHM Khodabakhshi et al 10,43
DDX3X Tier 1 GE13, FE52 Reddy et al 37,53
DTX1 Tier 1 GE8, aSHM Zhang et al 11,12,54
DUSP2 Tier 1 GE1, aSHM Lohr et al 2,45
EBF1 Tier 1 GE55, FE56, aSHM Bohle et al 2,20,57
EEF1A1 Tier 1 GE58 Chapuy et al 6,20
EP300 Tier 1 GE48, FE48 Pasqualucci et al 12
ETS1 Tier 1 GE17, aSHM Morin et al 43
ETV6 Tier 1 GE1, FE59, aSHM Lohr et al
EZH2 Tier 1 GE60, FE61 Morin et al 11,53
FAS Tier 1 GE62, FE63 Scholl et al 7,17
FBXO11 Tier 1 GE64, FE65 Arthur et al 39,49
FBXW7 Tier 1 GE8, FE66 Zhang et al
FOXO1 Tier 1 GE17, FE67 Morin et al 37,45
GNA13 Tier 1 GE17, FE68 Morin et al 11,20
GNAI2 Tier 1 GE44, FE68 Morin et al 2,28
GRB2 Tier 1 GE69 Pasqualucci et al
GRHPR Tier 1 GE70, aSHM Schmitz et al
HIST1H1B Tier 1 GE58, aSHM Chapuy et al 10,25
HIST1H1C Tier 1 GE17, aSHM Morin et al 43
HIST1H1D Tier 1 GE44, aSHM Morin et al 10,38
HIST1H1E Tier 1 GE1, aSHM Lohr et al 10,20,28
HIST1H2AC Tier 1 GE44, aSHM Morin et al 10
HIST1H2AM Tier 1 GE58, aSHM Chapuy et al 10,43
HIST1H2BC Tier 1 GE1, aSHM Lohr et al 10,53
HIST1H2BK Tier 1 GE8, aSHM Zhang et al 12,43
HIST1H3B Tier 1 GE1, aSHM Lohr et al 20
HIST2H2BE Tier 1 GE58, aSHM Chapuy et al
HLA-A Tier 1 GE1, FE71 Lohr et al 5
HLA-B Tier 1 GE1, FE71 Lohr et al 3
HLA-C Tier 1 GE58, FE71 Chapuy et al 54
HLA-DMB Tier 1 GE6 Hubschmann et al
HNRNPU Tier 1 GE13 Reddy et al 43
HVCN1 Tier 1 GE58 Chapuy et al 10
IKZF3 Tier 1 GE17, FE72 Morin et al 43
IL4R Tier 1 GE45, FE73, aSHM Duns et al 73
IRF4 Tier 1 GE17, aSHM Morin et al 2,53
IRF8 Tier 1 GE17, FE74, aSHM Morin et al 43,53
ITPKB Tier 1 GE70, FE75, aSHM Schmitz et al 2,20
JUNB Tier 1 GE1 Lohr et al 53 PASS
KLF2 Tier 1 GE69, aSHM Pasqualucci et al 2,5,38
KLHL14 Tier 1 GE8, FE76 Zhang et al
KLHL6 Tier 1 GE17, FE77, aSHM Morin et al 78
KMT2C Tier 1 GE8 Zhang et al 25,79,80
KMT2D Tier 1 GE17, FE81 Morin et al 5,12,15,28
KRAS Tier 1 GE1, FE82 Lohr et al
LRRN3 Tier 1 GE8 Zhang et al 25
LTB Tier 1 GE58, aSHM Chapuy et al 2,5
MEF2B Tier 1 GE17, FE83, aSHM Morin et al 15
MEF2C Tier 1 GE6, aSHM Hubschmann et al
MGA Tier 1 GE13, FE84 Reddy et al 38
MIR142 Tier 1 GE85, FE86, aSHM Kwanhian et al 28
MPEG1 Tier 1 GE44 Morin et al
MS4A1 Tier 1 GE87, FE87, aSHM Rushton et al 53
MTOR Tier 1 GE8, FE88 Zhang et al 43
MYC Tier 1 GE89, FE90, aSHM Pasqualucci et al 38,45,91
MYD88 Tier 1 GE92, FE92 Ngo et al 2,36
NFKBIA Tier 1 GE93, FE94 Thomas et al 3,22
NFKBIE Tier 1 GE95, FE96 Morin et al 19,97
NFKBIZ Tier 1 GE95, FE64, aSHM Morin et al
NOL9 Tier 1 GE70 Schmitz et al 7
NOTCH1 Tier 1 GE69, FE98 Pasqualucci et al 11,12,15
NOTCH2 Tier 1 GE8, FE99 Zhang et al 12,15
OSBPL10 Tier 1 GE8, aSHM Zhang et al
P2RY8 Tier 1 GE1, FE68 Lohr et al 2,68
PIM1 Tier 1 GE89, FE100, aSHM Pasqualucci et al 2,24,45
PIM2 Tier 1 GE13, aSHM Reddy et al 20
POU2AF1 Tier 1 GE58, FE101, aSHM Chapuy et al 10
POU2F2 Tier 1 GE1, FE102 Lohr et al 10
PRDM1 Tier 1 GE103, FE103 Pasqualucci et al
PTEN Tier 1 GE13, FE104 Reddy et al 11
PTPN6 Tier 1 GE13, FE105 Reddy et al PASS
RB1 Tier 1 GE44, FE106 Morin et al 79
RFX7 Tier 1 GE64, FE107 Arthur et al 28
RHOA Tier 1 GE8, FE108 Zhang et al 39
RRAGC Tier 1 GE109, FE109 Okosun et al
S1PR2 Tier 1 GE17, FE68, aSHM Morin et al 2,68
SETD1B Tier 1 GE32, FE[@] Albuquerque et al
SF3B1 Tier 1 GE13, FE110 Reddy et al 11
SGK1 Tier 1 GE17, FE111, aSHM Morin et al 45
SIN3A Tier 1 GE58 Chapuy et al 12,28
SMARCA4 Tier 1 GE13, FE112 Reddy et al 10,39,nadeuGenomicEpigenomicInsights2020b?
SOCS1 Tier 1 GE17, FE113, aSHM Morin et al 2,114
SPEN Tier 1 GE32 Albuquerque et al 12,25
STAT3 Tier 1 GE17, FE115 Morin et al
STAT6 Tier 1 GE116, FE117 Yildiz et al 118
TAF1 Tier 1 GE44 Morin et al 7
TBL1XR1 Tier 1 GE1, FE119 Lohr et al 2,12
TET2 Tier 1 GE32, FE120 Albuquerque et al 57
TMEM30A Tier 1 GE17, FE121 Morin et al
TMSB4X Tier 1 GE13, aSHM Reddy et al 2
TNFAIP3 Tier 1 GE122, FE122 Compagno et al 2,123,124
TNFRSF14 Tier 1 GE17, FE[@] Morin et al 7,125
TOX Tier 1 GE13 Reddy et al
TP53 Tier 1 GE17, FE126 Morin et al 12,15,75,127
UBE2A Tier 1 GE1 Lohr et al 20
WEE1 Tier 1 GE70 Schmitz et al 20
XPO1 Tier 1 GE128, FE129 Mareschal et al 130
ZC3H12A Tier 1 GE58, FE131 Chapuy et al
ZFP36L1 Tier 1 GE17, aSHM Morin et al 20,43
ZNF292 Tier 1 GE13 Reddy et al
ZNF608 Tier 1 GE44 Morin et al 10

Tier 2, low-confidence DLBCL genes

210 total

Gene Summary First DLBCL study Other entities QC result
ABI3BP Tier 2 GE44 Morin et al PASS
ADAMTS1 Tier 2 GE6 Hubschmann et al PASS
ADAMTSL3 Tier 2 GE69 Pasqualucci et al
AICDA Tier 2 GE64, aSHM Arthur et al
AKAP8 Tier 2 GE69 Pasqualucci et al
ANKLE2 Tier 2 GE69 Pasqualucci et al
ANKRD12 Tier 2 GE6 Hubschmann et al PASS
ANKRD17 Tier 2 GE8 Zhang et al
ARAP2 Tier 2 GE44 Morin et al
ARID5B Tier 2 GE13 Reddy et al 54 PASS
ASXL3 Tier 2 GE32 Albuquerque et al
ATR Tier 2 GE13 Reddy et al PASS
BCL11A Tier 2 GE58, aSHM Chapuy et al
BCL2L10 Tier 2 GE69 Pasqualucci et al
BCR Tier 2 GE1 Lohr et al
BIRC3 Tier 2 GE64, aSHM Arthur et al 15,45,123
BLK Tier 2 GE, aSHM
BRINP3 Tier 2 GE13 Reddy et al PASS
BRSK1 Tier 2 GE69 Pasqualucci et al
BTBD3 Tier 2 GE8 Zhang et al
C12orf35 Tier 2 GE69 Pasqualucci et al
CADPS2 Tier 2 GE6 Hubschmann et al PASS
CAMTA1 Tier 2 GE69 Pasqualucci et al
CASP8 Tier 2 GE13 Reddy et al
CD22 Tier 2 GE13 Reddy et al PASS
CD274 Tier 2 GE17 Morin et al
CD36 Tier 2 GE69 Pasqualucci et al
CD44 Tier 2 GE64, aSHM Arthur et al
CD74 Tier 2 GE64, aSHM Arthur et al
CDH9 Tier 2 GE44 Morin et al PASS
CEP164 Tier 2 GE32 Albuquerque et al
CNOT2 Tier 2 GE6 Hubschmann et al PASS
CNTNAP5 Tier 2 GE44 Morin et al PASS
COQ7 Tier 2 GE58 Chapuy et al PASS
CPS1 Tier 2 GE1 Lohr et al
CRIP1 Tier 2 GE58 Chapuy et al PASS
CXCR5 Tier 2 GE70 Schmitz et al 53
CYTSB Tier 2 GE69 Pasqualucci et al
DAZAP1 Tier 2 GE19 Pararajalingam et al
DCHS1 Tier 2 GE69 Pasqualucci et al
DDX10 Tier 2 GE8 Zhang et al
DHX16 Tier 2 GE6 Hubschmann et al PASS
DNAH5 Tier 2 GE44 Morin et al 38 PASS
DNM2 Tier 2 GE6 Hubschmann et al PASS
DNMT3B Tier 2 GE32 Albuquerque et al
DOCK1 Tier 2 GE58 Chapuy et al PASS
DPYD Tier 2 GE69 Pasqualucci et al
DSC3 Tier 2 GE69 Pasqualucci et al
DSEL Tier 2 GE44 Morin et al
DSG4 Tier 2 GE44 Morin et al PASS
DUSP27 Tier 2 GE69 Pasqualucci et al
DUSP9 Tier 2 GE69 Pasqualucci et al
EIF2AK3 Tier 2 GE70, aSHM Schmitz et al
ERAP2 Tier 2 GE32 Albuquerque et al
EZR Tier 2 GE, aSHM 5
FAM102A Tier 2 GE, aSHM
FANK1 Tier 2 GE, aSHM
FAT2 Tier 2 GE17 Morin et al
FAT4 Tier 2 GE44 Morin et al 49,79 PASS
FBXO31 Tier 2 GE69 Pasqualucci et al
FCRL3 Tier 2 GE, aSHM
FNBP1 Tier 2 GE, aSHM
FOXC1 Tier 2 GE70 Schmitz et al
FOXP1 Tier 2 GE13, aSHM Reddy et al PASS
FUBP1 Tier 2 GE13 Reddy et al PASS
GABRA1 Tier 2 GE1 Lohr et al
GABRA2 Tier 2 GE58 Chapuy et al
GOLGA5 Tier 2 GE13 Reddy et al PASS
GPC5 Tier 2 GE70 Schmitz et al
GSG2 Tier 2 GE70 Schmitz et al
H1FOO Tier 2 GE1 Lohr et al
HDAC7 Tier 2 GE44 Morin et al PASS
HIST1H2AG Tier 2 GE44 Morin et al 10,12,43 PASS
HIST1H2AL Tier 2 GE1 Lohr et al
HIST1H2BO Tier 2 GE1 Lohr et al
HIST1H3A Tier 2 GE1 Lohr et al
HLA-DMA Tier 2 GE58 Chapuy et al
HMGB1 Tier 2 GE69 Pasqualucci et al
HNF1B Tier 2 GE69 Pasqualucci et al
HNRNPD Tier 2 GE13 Reddy et al
HNRNPH1 Tier 2 GE19 Pararajalingam et al
ID3 Tier 2 GE70 Schmitz et al 7,39
IFNGR1 Tier 2 GE44 Morin et al PASS
IGLL5 Tier 2 GE58, aSHM Chapuy et al 5,22,43
IKBKB Tier 2 GE13 Reddy et al 3,123 PASS
IKBKE Tier 2 GE6 Hubschmann et al PASS
IL16 Tier 2 GE13 Reddy et al
IL6 Tier 2 GE58 Chapuy et al PASS
INO80 Tier 2 GE13 Reddy et al
IRF1 Tier 2 GE6, aSHM Hubschmann et al PASS
JAK1 Tier 2 GE13 Reddy et al 53
JAK3 Tier 2 GE13 Reddy et al
KCMF1 Tier 2 GE13 Reddy et al PASS
KDM2B Tier 2 GE69 Pasqualucci et al
KLHL21 Tier 2 GE70 Schmitz et al
KRTAP5-5 Tier 2 GE1 Lohr et al
LAMA5 Tier 2 GE70 Schmitz et al
LAPTM5 Tier 2 GE6, aSHM Hubschmann et al PASS
LCOR Tier 2 GE[@]
LPP Tier 2 GE64, aSHM Arthur et al
LRP12 Tier 2 GE6 Hubschmann et al PASS
LYN Tier 2 GE58 Chapuy et al PASS
MAGEC3 Tier 2 GE69 Pasqualucci et al
MAGT1 Tier 2 GE13 Reddy et al PASS
MALAT1 Tier 2 GE64, aSHM Arthur et al
MAP2K1 Tier 2 GE132 Shin et al 133
MCL1 Tier 2 GE13 Reddy et al 43,45 PASS
MECOM Tier 2 GE13 Reddy et al PASS
MED12L Tier 2 GE69 Pasqualucci et al
MET Tier 2 GE13 Reddy et al PASS
MIR155HG Tier 2 GE, aSHM
MPDZ Tier 2 GE44 Morin et al 20 PASS
MSH6 Tier 2 GE13 Reddy et al PASS
MTMR8 Tier 2 GE69 Pasqualucci et al
MYBPC2 Tier 2 GE70 Schmitz et al
MYO1G Tier 2 GE69 Pasqualucci et al
MYOM2 Tier 2 GE69 Pasqualucci et al
NAV1 Tier 2 GE58 Chapuy et al
NCOA3 Tier 2 GE, aSHM
NEAT1 Tier 2 GE64, aSHM Arthur et al
NF1 Tier 2 GE8 Zhang et al
NLRP5 Tier 2 GE44 Morin et al PASS
ODZ2 Tier 2 GE44 Morin et al PASS
OFD1 Tier 2 GE69 Pasqualucci et al
OR6K3 Tier 2 GE1 Lohr et al
P2RX5 Tier 2 GE44, aSHM Morin et al PASS
PAPOLG Tier 2 GE70 Schmitz et al
PASD1 Tier 2 GE1 Lohr et al
PASK Tier 2 GE44 Morin et al PASS
PAX5 Tier 2 GE89, aSHM Pasqualucci et al
PCDHB11 Tier 2 GE44 Morin et al PASS
PCDHB6 Tier 2 GE1 Lohr et al
PCLO Tier 2 GE1 Lohr et al
PDGFC Tier 2 GE1 Lohr et al
PDS5B Tier 2 GE44 Morin et al 6 PASS
PIK3CD Tier 2 GE8 Zhang et al
PIK3R1 Tier 2 GE8 Zhang et al 43
PMS1 Tier 2 GE69 Pasqualucci et al
PNPO Tier 2 GE6 Hubschmann et al PASS
PPP2R5A Tier 2 GE69 Pasqualucci et al
PRKCB Tier 2 GE44 Morin et al PASS
PRKDC Tier 2 GE70 Schmitz et al 6
PRPS1 Tier 2 GE58 Chapuy et al PASS
PTPN21 Tier 2 GE1 Lohr et al
PTPRD Tier 2 GE2 Dreval et al 7
RAC2 Tier 2 GE6 Hubschmann et al PASS
RAPGEF1 Tier 2 GE17 Morin et al
RASGEF1A Tier 2 GE69 Pasqualucci et al
RBP3 Tier 2 GE1 Lohr et al 11
RCC Tier 2 GE, aSHM
RFTN1 Tier 2 GE64, aSHM Arthur et al 45
RFXAP Tier 2 GE
RGAG1 Tier 2 GE69 Pasqualucci et al
RHEX Tier 2 GE64, aSHM Arthur et al
RHOH Tier 2 GE89, aSHM Pasqualucci et al
RUBCNL Tier 2 GE, aSHM
S1PR1 Tier 2 GE1 Lohr et al 19
SAMD9L Tier 2 GE44 Morin et al PASS
SEL1L3 Tier 2 GE70, aSHM Schmitz et al
SEPTIN9 Tier 2 GE, aSHM
SERPINA1 Tier 2 GE69 Pasqualucci et al
SERPINA9 Tier 2 GE64, aSHM Arthur et al
SETD2 Tier 2 GE8 Zhang et al
SETD5 Tier 2 GE13 Reddy et al 75 PASS
SIAH2 Tier 2 GE6 Hubschmann et al 20 PASS
SLC34A2 Tier 2 GE6 Hubschmann et al PASS
SLC38A8 Tier 2 GE1 Lohr et al
SLITRK6 Tier 2 GE1 Lohr et al
SMARCA1 Tier 2 GE69 Pasqualucci et al
SMEK1 Tier 2 GE8 Zhang et al
SRPX Tier 2 GE1 Lohr et al
SRRM2 Tier 2 GE44 Morin et al 22 PASS
ST6GAL1 Tier 2 GE64, aSHM Arthur et al
STAT5B Tier 2 GE13 Reddy et al 75
SYN2 Tier 2 GE1 Lohr et al
SYPL1 Tier 2 GE44 Morin et al PASS
TAP1 Tier 2 GE70 Schmitz et al
TBC1D4 Tier 2 GE64, aSHM Arthur et al
TBP Tier 2 GE1 Lohr et al
TCL1A Tier 2 GE13, aSHM Reddy et al 28
TGFBR2 Tier 2 GE13 Reddy et al PASS
TIPARP Tier 2 GE13 Reddy et al PASS
TLL2 Tier 2 GE69 Pasqualucci et al
TLR2 Tier 2 GE58 Chapuy et al 15 PASS
TMSL3 Tier 2 GE1 Lohr et al
TNF Tier 2 GE1 Lohr et al
TRAF3 Tier 2 GE69 Pasqualucci et al 123,134
TRAF6 Tier 2 GE6 Hubschmann et al PASS
TRIP12 Tier 2 GE
TSC22D1 Tier 2 GE69 Pasqualucci et al
UBE2J1 Tier 2 GE70, aSHM Schmitz et al
UBR5 Tier 2 GE32 Albuquerque et al 19
UHRF1BP1 Tier 2 GE32 Albuquerque et al
UNC5B Tier 2 GE6 Hubschmann et al PASS
UNC5C Tier 2 GE1 Lohr et al
UNC5D Tier 2 GE1 Lohr et al
USP7 Tier 2 GE64 Arthur et al 28
VAX1 Tier 2 GE1 Lohr et al
WDFY3 Tier 2 GE44 Morin et al PASS
WNK1 Tier 2 GE6 Hubschmann et al 38,57 PASS
XBP1 Tier 2 GE, aSHM
YY1 Tier 2 GE13 Reddy et al PASS
ZCCHC7 Tier 2 GE64, aSHM Arthur et al
ZEB2 Tier 2 GE13 Reddy et al
ZFX Tier 2 GE13 Reddy et al PASS
ZNF217 Tier 2 GE6 Hubschmann et al 20 PASS
ZNF385B Tier 2 GE1 Lohr et al
ZNF423 Tier 2 GE58 Chapuy et al PASS
ZNF521 Tier 2 GE69 Pasqualucci et al
ZWILCH Tier 2 GE69 Pasqualucci et al

Tier 3, retired DLBCL genes

387 total

Gene Summary First DLBCL study Other entities QC result
ABCA3 Tier 3 GE8 Zhang et al 15
ABCA4 Tier 3 GE8 Zhang et al
ABCB1 Tier 3 GE4 Fan et al
ACE Tier 3 GE8 Zhang et al 11
ACSM3 Tier 3 GE8 Zhang et al
ACSS2 Tier 3 GE8 Zhang et al
ACSS3 Tier 3 GE8 Zhang et al
ACTN1 Tier 3 GE8 Zhang et al
ADAM2 Tier 3 GE8 Zhang et al
ADAMTS15 Tier 3 GE8 Zhang et al
ADH7 Tier 3 GE8 Zhang et al
AFAP1L2 Tier 3 GE8 Zhang et al
AGA Tier 3 GE4 Fan et al
AHR Tier 3 GE8 Zhang et al
AKAP9 Tier 3 GE8 Zhang et al
ALAS1 Tier 3 GE8 Zhang et al
ALDH1L2 Tier 3 GE8 Zhang et al
AMAC1 Tier 3 GE8 Zhang et al
AMIGO3 Tier 3 GE8 Zhang et al
AMPH Tier 3 GE8 Zhang et al
ANK2 Tier 3 GE8 Zhang et al 79
ANKRD44 Tier 3 GE8 Zhang et al
ANTXR1 Tier 3 GE8 Zhang et al
AP1G2 Tier 3 GE8 Zhang et al
APBB1 Tier 3 GE8 Zhang et al
APC Tier 3 GE8 Zhang et al
APMAP Tier 3 GE4 Fan et al
APOA5 Tier 3 GE8 Zhang et al
APP Tier 3 GE8 Zhang et al
ARID1B Tier 3 GE13 Reddy et al FAIL
ATIC Tier 3 GE8 Zhang et al
ATP10A Tier 3 GE8 Zhang et al
ATP1A2 Tier 3 GE8 Zhang et al
ATP2A3 Tier 3 GE8 Zhang et al
ATP6V0A1 Tier 3 GE4 Fan et al
B4GALNT2 Tier 3 GE8 Zhang et al
BAZ1A Tier 3 GE8 Zhang et al
BCAT2 Tier 3 GE8 Zhang et al
BLM Tier 3 GE8 Zhang et al
BMPR1A Tier 3 GE8 Zhang et al
BRCA1 Tier 3 GE4 Fan et al
BRCA2 Tier 3 GE8 Zhang et al
BRD4 Tier 3 GE8 Zhang et al 11
BSCL2 Tier 3 GE8 Zhang et al
BTAF1 Tier 3 GE8 Zhang et al
C9 Tier 3 GE8 Zhang et al
CAD Tier 3 GE8 Zhang et al 11
CAPN5 Tier 3 GE8 Zhang et al
CAPN7 Tier 3 GE8 Zhang et al
CBLB Tier 3 GE13 Reddy et al FAIL
CBX3 Tier 3 GE4 Fan et al
CCDC132 Tier 3 GE8 Zhang et al
CCDC46 Tier 3 GE8 Zhang et al
CCDC97 Tier 3 GE8 Zhang et al
CCL4 Tier 3 GE58 Chapuy et al FAIL
CCNF Tier 3 GE8 Zhang et al 135
CDC123 Tier 3 GE8 Zhang et al
CDC73 Tier 3 GE13 Reddy et al 11 FAIL
CDH1 Tier 3 GE4 Fan et al
CDH10 Tier 3 GE8 Zhang et al
CDH7 Tier 3 GE8 Zhang et al
CDH8 Tier 3 GE13 Reddy et al 79 FAIL
CDK3 Tier 3 GE8 Zhang et al
CDKN1A Tier 3 GE4 Fan et al
CECR1 Tier 3 GE8 Zhang et al
CELSR2 Tier 3 GE8 Zhang et al
CGN Tier 3 GE4 Fan et al
CHD1 Tier 3 GE13 Reddy et al FAIL
CHD3 Tier 3 GE8 Zhang et al
CHEK2 Tier 3 GE4 Fan et al
CHRM5 Tier 3 GE8 Zhang et al
CHST2 Tier 3 GE13 Reddy et al FAIL
CIC Tier 3 GE8 Zhang et al
CNGA4 Tier 3 GE8 Zhang et al
CNOT6 Tier 3 GE8 Zhang et al
CNP Tier 3 GE8 Zhang et al
CNTN6 Tier 3 GE8 Zhang et al
COL5A2 Tier 3 GE8 Zhang et al
CORO2A Tier 3 GE8 Zhang et al
CORO7 Tier 3 GE8 Zhang et al
CRELD2 Tier 3 GE8 Zhang et al
CRTC3 Tier 3 GE8 Zhang et al
CSNK1A1 Tier 3 GE4 Fan et al
CSNK2A1 Tier 3 GE4 Fan et al
CST7 Tier 3 GE8 Zhang et al
CTNNA3 Tier 3 GE8 Zhang et al
CYP24A1 Tier 3 GE8 Zhang et al
CYP2C18 Tier 3 GE8 Zhang et al
CYYR1 Tier 3 GE4 Fan et al
DCAF6 Tier 3 GE13 Reddy et al FAIL
DDB1 Tier 3 GE8 Zhang et al
DGCR8 Tier 3 GE4 Fan et al
DHX33 Tier 3 GE4 Fan et al
DIAPH3 Tier 3 GE8 Zhang et al
DICER1 Tier 3 GE13 Reddy et al FAIL
DIP2B Tier 3 GE8 Zhang et al
DLGAP1 Tier 3 GE8 Zhang et al 11
DMXL1 Tier 3 GE8 Zhang et al
DNMT3A Tier 3 GE13 Reddy et al FAIL
DOCK2 Tier 3 GE8 Zhang et al
DOCK5 Tier 3 GE4 Fan et al
DOLK Tier 3 GE8 Zhang et al
DSC2 Tier 3 GE8 Zhang et al
DSCAML1 Tier 3 GE8 Zhang et al
DSG2 Tier 3 GE8 Zhang et al
DSP Tier 3 GE8 Zhang et al
DUOXA2 Tier 3 GE8 Zhang et al
DUPD1 Tier 3 GE8 Zhang et al
DYNC1H1 Tier 3 GE8 Zhang et al
DYNC1I1 Tier 3 GE8 Zhang et al
ECGF1 Tier 3 GE8 Zhang et al
ECT2L Tier 3 GE4 Fan et al
EGFR Tier 3 GE4 Fan et al
EPHA3 Tier 3 GE8 Zhang et al
EPHA5 Tier 3 GE8 Zhang et al
EPHA7 Tier 3 GE8 Zhang et al 53
ERBB3 Tier 3 GE8 Zhang et al
ERN2 Tier 3 GE8 Zhang et al
ETNPPL Tier 3 GE8 Zhang et al
EXTL3 Tier 3 GE8 Zhang et al
FAIM Tier 3 GE4 Fan et al
FAM161A Tier 3 GE4 Fan et al
FAM38B Tier 3 GE44 Morin et al FAIL
FAM62C Tier 3 GE8 Zhang et al
FANCD2 Tier 3 GE8 Zhang et al
FGD3 Tier 3 GE8 Zhang et al
FGFR1 Tier 3 GE8 Zhang et al
FIGN Tier 3 GE8 Zhang et al
FLNA Tier 3 GE4 Fan et al
FLNC Tier 3 GE8 Zhang et al
FLT1 Tier 3 GE4 Fan et al
FMO2 Tier 3 GE8 Zhang et al
FN1 Tier 3 GE4 Fan et al
FNDC1 Tier 3 GE44 Morin et al FAIL
FRMPD1 Tier 3 GE8 Zhang et al
FUT5 Tier 3 GE58 Chapuy et al FAIL
FZD1 Tier 3 GE4 Fan et al
GABRG1 Tier 3 GE8 Zhang et al
GAK Tier 3 GE6 Hubschmann et al FAIL
GATA2 Tier 3 GE4 Fan et al
GATA3 Tier 3 GE4 Fan et al
GCN1L1 Tier 3 GE8 Zhang et al
GJA8 Tier 3 GE8 Zhang et al
GJB4 Tier 3 GE8 Zhang et al
GNAS Tier 3 GE13 Reddy et al FAIL
GOPC Tier 3 GE8 Zhang et al
GPD2 Tier 3 GE8 Zhang et al
GPR133 Tier 3 GE8 Zhang et al
GPR15 Tier 3 GE8 Zhang et al
GREM2 Tier 3 GE8 Zhang et al
GRIA2 Tier 3 GE8 Zhang et al
GRM5 Tier 3 GE8 Zhang et al
H6PD Tier 3 GE8 Zhang et al
HACE1 Tier 3 GE8 Zhang et al
HCK Tier 3 GE8 Zhang et al
HFE Tier 3 GE4 Fan et al
HIPK3 Tier 3 GE8 Zhang et al
HIST1H4I Tier 3 GE8 Zhang et al
HK3 Tier 3 GE8 Zhang et al
HLA-DQA1 Tier 3 GE6 Hubschmann et al FAIL
HLA-DRB1 Tier 3 GE4 Fan et al
HNRNPR Tier 3 GE8 Zhang et al
HRAS Tier 3 GE13 Reddy et al 38 FAIL
HSF2 Tier 3 GE8 Zhang et al
IDH1 Tier 3 GE8 Zhang et al
IER2 Tier 3 GE44 Morin et al FAIL
IL6ST Tier 3 GE4 Fan et al
INSC Tier 3 GE8 Zhang et al
INTS6 Tier 3 GE8 Zhang et al
IQGAP1 Tier 3 GE8 Zhang et al
IQUB Tier 3 GE8 Zhang et al
ITGA2 Tier 3 GE8 Zhang et al
ITGA8 Tier 3 GE8 Zhang et al
ITGB3 Tier 3 GE8 Zhang et al
ITGB4 Tier 3 GE4 Fan et al
ITPR1 Tier 3 GE4 Fan et al
JAG1 Tier 3 GE8 Zhang et al
JAKMIP2 Tier 3 GE8 Zhang et al
KCNA3 Tier 3 GE8 Zhang et al
KCNAB3 Tier 3 GE8 Zhang et al
KCNJ6 Tier 3 GE8 Zhang et al
KCNT2 Tier 3 GE8 Zhang et al
KDR Tier 3 GE8 Zhang et al
KIF21B Tier 3 GE8 Zhang et al
KIT Tier 3 GE8 Zhang et al
KITLG Tier 3 GE4 Fan et al
KLB Tier 3 GE8 Zhang et al
KLC3 Tier 3 GE8 Zhang et al
KLF4 Tier 3 GE8 Zhang et al
KLRC4 Tier 3 GE4 Fan et al
KRT6A Tier 3 GE8 Zhang et al
LEPR Tier 3 GE4 Fan et al
LEPREL1 Tier 3 GE8 Zhang et al
LIFR Tier 3 GE8 Zhang et al
LILRA2 Tier 3 GE8 Zhang et al
LIN54 Tier 3 GE13 Reddy et al FAIL
LIN7C Tier 3 GE8 Zhang et al
LPHN2 Tier 3 GE8 Zhang et al
LRAP Tier 3 GE8 Zhang et al
LRIG3 Tier 3 GE8 Zhang et al
LRP1 Tier 3 GE8 Zhang et al
LRP10 Tier 3 GE8 Zhang et al
LRP1B Tier 3 GE8 Zhang et al 7
LRP3 Tier 3 GE8 Zhang et al
LYST Tier 3 GE8 Zhang et al
MAP2K3 Tier 3 GE4 Fan et al
MAP4K4 Tier 3 GE13 Reddy et al FAIL
MARCHF7 Tier 3 GE8 Zhang et al
MARK1 Tier 3 GE13 Reddy et al FAIL
MBL2 Tier 3 GE8 Zhang et al
MCM8 Tier 3 GE4 Fan et al
MED13L Tier 3 GE8 Zhang et al
MIB1 Tier 3 GE8 Zhang et al
MLH1 Tier 3 GE4 Fan et al
MMEL1 Tier 3 GE4 Fan et al
MN1 Tier 3 GE8 Zhang et al
MORC2 Tier 3 GE8 Zhang et al
MPL Tier 3 GE8 Zhang et al
MSH2 Tier 3 GE13 Reddy et al FAIL
MSN Tier 3 GE4 Fan et al
MTMR3 Tier 3 GE8 Zhang et al
MYB Tier 3 GE13 Reddy et al 5 FAIL
MYL7 Tier 3 GE8 Zhang et al
MYO5C Tier 3 GE8 Zhang et al
MYRIP Tier 3 GE8 Zhang et al
NANOG Tier 3 GE58 Chapuy et al FAIL
NCOR1 Tier 3 GE13 Reddy et al FAIL
NDUFS1 Tier 3 GE8 Zhang et al
NELL2 Tier 3 GE8 Zhang et al
NFIB Tier 3 GE8 Zhang et al
NFKB2 Tier 3 GE13 Reddy et al 53 FAIL
NFX1 Tier 3 GE8 Zhang et al
NGFR Tier 3 GE8 Zhang et al
NIPBL Tier 3 GE8 Zhang et al
NLGN2 Tier 3 GE8 Zhang et al
NLRP7 Tier 3 GE8 Zhang et al
NLRP8 Tier 3 GE58 Chapuy et al FAIL
NOTCH3 Tier 3 GE4 Fan et al
NPHP1 Tier 3 GE8 Zhang et al
NPY2R Tier 3 GE8 Zhang et al
NR2F2 Tier 3 GE6 Hubschmann et al FAIL
NRXN2 Tier 3 GE8 Zhang et al 11
NSD1 Tier 3 GE8 Zhang et al
NSD2 Tier 3 GE8 Zhang et al 15
NUP153 Tier 3 GE4 Fan et al
ONECUT1 Tier 3 GE8 Zhang et al
PABPC1 Tier 3 GE4 Fan et al
PADI1 Tier 3 GE8 Zhang et al
PAPPA2 Tier 3 GE8 Zhang et al
PBX1 Tier 3 GE8 Zhang et al
PCCB Tier 3 GE8 Zhang et al
PCDE1C Tier 3 GE8 Zhang et al
PCDH7 Tier 3 GE8 Zhang et al
PCDHB1 Tier 3 GE8 Zhang et al
PCDHB15 Tier 3 GE8 Zhang et al
PCDHB3 Tier 3 GE8 Zhang et al
PCDHB5 Tier 3 GE8 Zhang et al
PCDHGA2 Tier 3 GE8 Zhang et al
PDE1C Tier 3 GE8 Zhang et al
PDE4DIP Tier 3 GE58 Chapuy et al FAIL
PDGFRA Tier 3 GE8 Zhang et al
PDGFRB Tier 3 GE4 Fan et al
PDIA2 Tier 3 GE8 Zhang et al
PDZRN3 Tier 3 GE8 Zhang et al 43
PDZRN4 Tier 3 GE8 Zhang et al
PFN1 Tier 3 GE4 Fan et al
PGR Tier 3 GE4 Fan et al
PHF6 Tier 3 GE13 Reddy et al 57 FAIL
PKD1 Tier 3 GE44 Morin et al FAIL
PLA2G4B Tier 3 GE8 Zhang et al
PLCB4 Tier 3 GE4 Fan et al
PLCG2 Tier 3 GE4 Fan et al 43
PLEKHA7 Tier 3 GE8 Zhang et al
PNLIPRP1 Tier 3 GE8 Zhang et al
PNPT1 Tier 3 GE8 Zhang et al
POGZ Tier 3 GE44 Morin et al FAIL
POLD3 Tier 3 GE4 Fan et al
POLE Tier 3 GE8 Zhang et al
POLQ Tier 3 GE4 Fan et al
PPARGC1A Tier 3 GE8 Zhang et al
PPP2R2B Tier 3 GE4 Fan et al
PPWD1 Tier 3 GE8 Zhang et al
PRDM16 Tier 3 GE8 Zhang et al
PRKCB1 Tier 3 GE8 Zhang et al
PRKCQ Tier 3 GE8 Zhang et al
PROS1 Tier 3 GE8 Zhang et al
PRSS7 Tier 3 GE8 Zhang et al
PTCH1 Tier 3 GE4 Fan et al
PTPN14 Tier 3 GE8 Zhang et al
PTPN23 Tier 3 GE44 Morin et al FAIL
PTPRF Tier 3 GE8 Zhang et al
PTPRK Tier 3 GE13 Reddy et al FAIL
PTPRT Tier 3 GE8 Zhang et al
PXK Tier 3 GE8 Zhang et al
RAB3GAP1 Tier 3 GE8 Zhang et al
RAD9A Tier 3 GE58 Chapuy et al FAIL
RAF1 Tier 3 GE4 Fan et al 38
RAPGEF2 Tier 3 GE8 Zhang et al
RAPGEF3 Tier 3 GE4 Fan et al
RARA Tier 3 GE13 Reddy et al FAIL
RBM15B Tier 3 GE8 Zhang et al
RECQL4 Tier 3 GE4 Fan et al
RELN Tier 3 GE8 Zhang et al 25
RET Tier 3 GE4 Fan et al 11
RFC1 Tier 3 GE8 Zhang et al
RGS1 Tier 3 GE8 Zhang et al 53
RHPN2 Tier 3 GE4 Fan et al
RIF1 Tier 3 GE4 Fan et al
RIMS4 Tier 3 GE4 Fan et al
ROR2 Tier 3 GE8 Zhang et al
RPTOR Tier 3 GE4 Fan et al
RSL1D1 Tier 3 GE8 Zhang et al
RUNDC1 Tier 3 GE8 Zhang et al
RUNX1 Tier 3 GE13 Reddy et al FAIL
RYR1 Tier 3 GE8 Zhang et al
SAPS3 Tier 3 GE8 Zhang et al
SARM1 Tier 3 GE44 Morin et al FAIL
SCYL1 Tier 3 GE8 Zhang et al
SEMA3A Tier 3 GE8 Zhang et al
SEMA3D Tier 3 GE8 Zhang et al
SEMA5A Tier 3 GE8 Zhang et al
SERINC2 Tier 3 GE8 Zhang et al
SH3PXD2B Tier 3 GE8 Zhang et al
SHMT2 Tier 3 GE8 Zhang et al
SIGLEC10 Tier 3 GE8 Zhang et al
SLC16A7 Tier 3 GE8 Zhang et al
SLC16A8 Tier 3 GE4 Fan et al
SLC4A8 Tier 3 GE8 Zhang et al
SLC5A1 Tier 3 GE8 Zhang et al
SLC9A5 Tier 3 GE8 Zhang et al
SMO Tier 3 GE4 Fan et al
SOS2 Tier 3 GE4 Fan et al
SOX6 Tier 3 GE8 Zhang et al
SPEG Tier 3 GE8 Zhang et al
SPTBN1 Tier 3 GE8 Zhang et al
ST8SIA3 Tier 3 GE8 Zhang et al
SULF2 Tier 3 GE8 Zhang et al
SYK Tier 3 GE13 Reddy et al FAIL
TAF1L Tier 3 GE8 Zhang et al
TAF4B Tier 3 GE8 Zhang et al
TECRL Tier 3 GE4 Fan et al
THBS4 Tier 3 GE8 Zhang et al
TIMM50 Tier 3 GE8 Zhang et al
TLN1 Tier 3 GE4 Fan et al
TLN2 Tier 3 GE8 Zhang et al
TLR4 Tier 3 GE4 Fan et al
TMC1 Tier 3 GE8 Zhang et al
TMEM161A Tier 3 GE8 Zhang et al
TMEM16E Tier 3 GE8 Zhang et al
TMEM63A Tier 3 GE8 Zhang et al
TNPO1 Tier 3 GE4 Fan et al
TPR Tier 3 GE4 Fan et al
TPRKB Tier 3 GE8 Zhang et al
TRIM37 Tier 3 GE8 Zhang et al
TRIP11 Tier 3 GE8 Zhang et al 20
TRRAP Tier 3 GE8 Zhang et al 12
TSC2 Tier 3 GE8 Zhang et al
TSHZ2 Tier 3 GE8 Zhang et al
TYRO3 Tier 3 GE4 Fan et al
UBXN11 Tier 3 GE4 Fan et al
UBXN2B Tier 3 GE4 Fan et al
UHRF1BP1L Tier 3 GE8 Zhang et al
UNC13B Tier 3 GE8 Zhang et al
UQCRC1 Tier 3 GE8 Zhang et al
VANGL1 Tier 3 GE4 Fan et al
VPS13A Tier 3 GE8 Zhang et al
WAC Tier 3 GE13 Reddy et al 12 FAIL
WDR65 Tier 3 GE8 Zhang et al
WDR66 Tier 3 GE8 Zhang et al
WDR67 Tier 3 GE8 Zhang et al
WIF1 Tier 3 GE8 Zhang et al
WNK4 Tier 3 GE8 Zhang et al
WT1 Tier 3 GE8 Zhang et al
XDH Tier 3 GE8 Zhang et al
ZBTB7A Tier 3 GE13 Reddy et al 24 FAIL
ZFAT Tier 3 GE13 Reddy et al FAIL
ZIC4 Tier 3 GE8 Zhang et al
ZMYM4 Tier 3 GE4 Fan et al
ZNF354A Tier 3 GE8 Zhang et al
ZNF366 Tier 3 GE8 Zhang et al
ZNF439 Tier 3 GE8 Zhang et al
ZNF474 Tier 3 GE8 Zhang et al
ZNF700 Tier 3 GE8 Zhang et al
ZNF790 Tier 3 GE8 Zhang et al
ZNF814 Tier 3 GE4 Fan et al
ZNF91 Tier 3 GE8 Zhang et al
ZP1 Tier 3 GE8 Zhang et al

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