Origins of DLBCL genes

Tier 1 DLBCL genes

126 total

Gene Summary First DLBCL study Other entities QC result
ACTB Tier 1 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al wienandGenomicAnalysesFlowsorted2019b?
ACTG1 Tier 1 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al 1,spinaGeneticsNodalMarginal2016b?
ARID1A Tier 1 GE2, FE3 Zhang et al 4,krysiakRecurrentSomaticMutations2017b?,rossiCodingGenomeSplenic2012c?,wienandGenomicAnalysesFlowsorted2019b?
ATM Tier 1 GE5 Reddy et al 6,7
B2M Tier 1 GE8, FEchalla-malladiCombinedGeneticInactivationa? Morin et al 9,reichelFlowSortingExome2015a?
BCL10 Tier 1 GE8, FE10 Morin et al russler-germainMutationsAssociatedProgression2023b?,spinaGeneticsNodalMarginal2016b?
BCL2 Tier 1 GE11, FE12 Tanaka et al 8,burkhardtClinicalRelevanceMolecular2022b?,sarkozyMutationalLandscapeGray2021a?
BCL6 Tier 1 GE8, FE12 Morin et al 4
BCL7A Tier 1 GE8, FEbalinas-gaviraFrequentMutationsAminoterminal2020b? Morin et al 13,krysiakRecurrentSomaticMutations2017b?,reichelFlowSortingExome2015a?
BIRC6 Tier 1 GE5 Reddy et al sarkozyMutationalLandscapeGray2021a?
BRAF Tier 1 GEtiacciBRAFMutationsHairycell2011a? Tiacci et al 4
BTG1 Tier 1 GE8, FEmlynarczykBTG1MutationYields2023b? Morin et al burkhardtClinicalRelevanceMolecular2022b?,sarkozyMutationalLandscapeGray2021a?
BTG2 Tier 1 GE8, CE14 Morin et al 4
BTK Tier 1 GEalbuquerqueEnhancingKnowledgeDiscovery2017a? Albuquerque et al krysiakRecurrentSomaticMutations2017b?
CARD11 Tier 1 GE15, FE15, CEzhaoExpressionPrognosticValue2016? Lenz et al 8,16,yanBCRTLRSignaling2012a?
CCND3 Tier 1 GE8, FE17 Morin et al 1,18,richterRecurrentMutationID32012a?
CD58 Tier 1 GE8, FEchalla-malladiCombinedGeneticInactivationa? Morin et al schneiderAlterationsCD58Gene2015a?
CD70 Tier 1 GE8 Morin et al russler-germainMutationsAssociatedProgression2023b?
CD79B Tier 1 GE8, FE19 Morin et al 20
CD83 Tier 1 GE21 Morin et al 20,dunsCharacterizationDLBCLPMBL2021b?,russler-germainMutationsAssociatedProgression2023b?
CDKN2A Tier 1 GE21, CEjardinDiffuseLargeBcell2010a? Morin et al 13,spinaGeneticsNodalMarginal2016b?
CIITA Tier 1 GE8, CE22 Morin et al mottokGenomicAlterationsCIITA2015b?
CREBBP Tier 1 GEpasqualucciInactivatingMutationsAcetyltransferase2011a?, FEpasqualucciInactivatingMutationsAcetyltransferase2011a? Pasqualucci et al 4,23,dunsCharacterizationDLBCLPMBL2021b?
CXCR4 Tier 1 GE24 Khodabakhshi et al 20,krysiakRecurrentSomaticMutations2017b?
CXCR5 Tier 1 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al mottokIntegrativeGenomicAnalysis2019b?
DDX3X Tier 1 GE5, FE25, CEkizhakeyilDDX3XLossAdverse2021? Reddy et al 17,mottokIntegrativeGenomicAnalysis2019b?
DTX1 Tier 1 GE2, FE26, CEmerirantaDeltex1MutationsPredict2017b? Zhang et al 4,27,rossiCodingGenomeSplenic2012c?
DUSP2 Tier 1 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al dunsCharacterizationDLBCLPMBL2021b?
EBF1 Tier 1 GE28 Bohle et al 29,reichelFlowSortingExome2015a?
EEF1A1 Tier 1 GEhubschmannMutationalMechanismsShaping2021b?, CEgongExpressionClinicalValue2021? Hubschmann et al reichelFlowSortingExome2015a?
EP300 Tier 1 GEpasqualucciInactivatingMutationsAcetyltransferase2011a?, FEpasqualucciInactivatingMutationsAcetyltransferase2011a? Pasqualucci et al rossiCodingGenomeSplenic2012c?
ETS1 Tier 1 GE8 Morin et al 20
ETV6 Tier 1 GElohrDiscoveryPrioritizationSomatic2012a?, CE22 Lohr et al
EZH2 Tier 1 GEmorinSomaticMutationsAltering2010a?, FEyapSomaticMutationsEZH22011b? Morin et al 4,mottokIntegrativeGenomicAnalysis2019b?
FAS Tier 1 GE30, FE31 Scholl et al spinaGeneticsNodalMarginal2016b?
FBXO11 Tier 1 GEhubschmannMutationalMechanismsShaping2021b?, FE32 Hubschmann et al 23,richterRecurrentMutationID32012a?
FBXW7 Tier 1 GE2, FE33 Zhang et al
FOXO1 Tier 1 GE8, FE34, CE34 Morin et al 17,dunsCharacterizationDLBCLPMBL2021b?
GNA13 Tier 1 GE8, FEmuppidiLossSignalingGa132014b? Morin et al 4,reichelFlowSortingExome2015a?
GNAI2 Tier 1 GE21 Morin et al 13
GRB2 Tier 1 GE35 Pasqualucci et al
GRHPR Tier 1 GE36 Arthur et al
HIST1H1B Tier 1 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al krysiakRecurrentSomaticMutations2017b?,sarkozyMutationalLandscapeGray2021a?
HIST1H1C Tier 1 GE8 Morin et al 20
HIST1H1D Tier 1 GE21 Morin et al 18,krysiakRecurrentSomaticMutations2017b?
HIST1H1E Tier 1 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al 13,krysiakRecurrentSomaticMutations2017b?,reichelFlowSortingExome2015a?
HIST1H2AC Tier 1 GE21 Morin et al krysiakRecurrentSomaticMutations2017b?
HIST1H2AM Tier 1 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al 20,krysiakRecurrentSomaticMutations2017b?
HIST1H2BC Tier 1 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al krysiakRecurrentSomaticMutations2017b?,mottokIntegrativeGenomicAnalysis2019b?
HIST1H2BK Tier 1 GE2 Zhang et al 20,rossiCodingGenomeSplenic2012c?
HIST1H3B Tier 1 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al reichelFlowSortingExome2015a?
HIST2H2BE Tier 1 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al
HLA-A Tier 1 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al 1
HLA-B Tier 1 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al wienandGenomicAnalysesFlowsorted2019b?
HLA-C Tier 1 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al 27
HLA-DMB Tier 1 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al
HNRNPU Tier 1 GE5 Reddy et al 20
HVCN1 Tier 1 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al krysiakRecurrentSomaticMutations2017b?
IKZF3 Tier 1 GE8 Morin et al 20
IL4R Tier 1 GEdunsCharacterizationDLBCLPMBL2021b?, FEviganoSomaticIL4RMutations2018b? Duns et al viganoSomaticIL4RMutations2018b?
IRF4 Tier 1 GE8 Morin et al mottokIntegrativeGenomicAnalysis2019b?
IRF8 Tier 1 GE8, FE37 Morin et al 20,mottokIntegrativeGenomicAnalysis2019b?
ITPKB Tier 1 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al reichelFlowSortingExome2015a?
JUNB Tier 1 GE5 Reddy et al mottokIntegrativeGenomicAnalysis2019b? PASS
KLF2 Tier 1 GE35 Pasqualucci et al 1,18
KLHL14 Tier 1 GE2, FE38, CE39 Zhang et al
KLHL6 Tier 1 GE8, FE40 Morin et al 41
KMT2C Tier 1 GE2 Zhang et al 42,43,sarkozyMutationalLandscapeGray2021a?
KMT2D Tier 1 GE8, FE44, CE45 Morin et al 1,6,13,rossiCodingGenomeSplenic2012c?
KRAS Tier 1 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
LCOR Tier 1 GE36 Arthur et al
LRRN3 Tier 1 GE2 Zhang et al sarkozyMutationalLandscapeGray2021a?
LTB Tier 1 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al 1
MEF2B Tier 1 GE8, FE46 Morin et al 6
MEF2C Tier 1 GE36, FE47 Arthur et al
MGA Tier 1 GE5, CE22 Reddy et al 18
MIR142 Tier 1 GEkwanhianMicroRNA142Mutated202012b? Kwanhian et al 13
MPEG1 Tier 1 GE21, CE22 Morin et al
MS4A1 Tier 1 GE45, FE45, CE45 Rushton et al mottokIntegrativeGenomicAnalysis2019b?
MTOR Tier 1 GE2 Zhang et al 20
MYC Tier 1 GEpasqualucciHypermutationMultipleProtooncogenes2001a?, FE48, CE49 Pasqualucci et al 18,50,dunsCharacterizationDLBCLPMBL2021b?
MYD88 Tier 1 GEngoOncogenicallyActiveMYD882011a?, FEngoOncogenicallyActiveMYD882011a?, CE22 Ngo et al yanBCRTLRSignaling2012a?
NFKBIA Tier 1 GE51 Thomas et al russler-germainMutationsAssociatedProgression2023b?,wienandGenomicAnalysesFlowsorted2019b?
NFKBIE Tier 1 GE52 Morin et al 9,53
NFKBIZ Tier 1 GE52, FE36 Morin et al
NOL9 Tier 1 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al spinaGeneticsNodalMarginal2016b?
NOTCH1 Tier 1 GE35, CE54 Pasqualucci et al 4,6,rossiCodingGenomeSplenic2012c?
NOTCH2 Tier 1 GE2, CEcampos-martinClinicalDiagnosticRelevance2017? Zhang et al 6,rossiCodingGenomeSplenic2012c?
OSBPL10 Tier 1 GE2, CEdobashiTP53OSBPL10Alterations2018b? Zhang et al
P2RY8 Tier 1 GElohrDiscoveryPrioritizationSomatic2012a?, FEmuppidiLossSignalingGa132014b? Lohr et al muppidiLossSignalingGa132014b?
PIM1 Tier 1 GEpasqualucciHypermutationMultipleProtooncogenes2001a?, CE22 Pasqualucci et al burkhardtClinicalRelevanceMolecular2022b?,dunsCharacterizationDLBCLPMBL2021b?
PIM2 Tier 1 GE36 Arthur et al reichelFlowSortingExome2015a?
POU2AF1 Tier 1 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al krysiakRecurrentSomaticMutations2017b?
POU2F2 Tier 1 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al krysiakRecurrentSomaticMutations2017b?
PRDM1 Tier 1 GEpasqualucciInactivationPRDM1BLIMP12006a?, FEpasqualucciInactivationPRDM1BLIMP12006a? Pasqualucci et al
PTEN Tier 1 GE5 Reddy et al 4
RB1 Tier 1 GE21 Morin et al 42
RFX7 Tier 1 GE36 Arthur et al 13
RHOA Tier 1 GE2, FE55 Zhang et al richterRecurrentMutationID32012a?
RRAGC Tier 1 GEokosunRecurrentMTORC1activatingRRAGC2016a?, FEortega-molinaOncogenicRagGTPase2019b? Okosun et al
S1PR2 Tier 1 GE8, FE56 Morin et al muppidiLossSignalingGa132014b?
SETD1B Tier 1 GEalbuquerqueEnhancingKnowledgeDiscovery2017a? Albuquerque et al
SF3B1 Tier 1 GE5 Reddy et al 4
SGK1 Tier 1 GE8, FEhartmannHighlyRecurrentMutations2016b?, CE22 Morin et al dunsCharacterizationDLBCLPMBL2021b?
SIN3A Tier 1 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al 13,rossiCodingGenomeSplenic2012c?
SMARCA4 Tier 1 GE5, FE57 Reddy et al krysiakRecurrentSomaticMutations2017b?,nadeuGenomicEpigenomicInsights2020b?,richterRecurrentMutationID32012a?
SOCS1 Tier 1 GE8, FEmelznerBiallelicMutationSOCS12005a? Morin et al wenigerMutationsTumorSuppressor2006a?
SPEN Tier 1 GEalbuquerqueEnhancingKnowledgeDiscovery2017a?, CE22 Albuquerque et al rossiCodingGenomeSplenic2012c?,sarkozyMutationalLandscapeGray2021a?
STAT3 Tier 1 GElohrDiscoveryPrioritizationSomatic2012a?, FEhuNovelMissenseM206K2013b? Lohr et al
STAT6 Tier 1 GEyildizActivatingSTAT6Mutations2015c?, FEyildizActivatingSTAT6Mutations2015c? Yildiz et al ritzRecurrentMutationsSTAT62009a?
TAF1 Tier 1 GE21 Morin et al spinaGeneticsNodalMarginal2016b?
TBL1XR1 Tier 1 GElohrDiscoveryPrioritizationSomatic2012a?, FEventuruttiTBL1XR1MutationsDrive2020b? Lohr et al rossiCodingGenomeSplenic2012c?
TET2 Tier 1 GEalbuquerqueEnhancingKnowledgeDiscovery2017a? Albuquerque et al 29
TMEM30A Tier 1 GE8, FEennishiTMEM30ALossoffunctionMutations2020b?, CEennishiTMEM30ALossoffunctionMutations2020b? Morin et al
TMSB4X Tier 1 GE2 Zhang et al
TNFAIP3 Tier 1 GEcompagnoMutationsMultipleGenes2009a?, FEcompagnoMutationsMultipleGenes2009a? Compagno et al rossiAlterationBIRC3Multiple2011a?,schmitzTNFAIP3A20Tumor2009a?
TNFRSF14 Tier 1 GE8, CE22 Morin et al cheungAcquiredTNFRSF14Mutations2010a?,spinaGeneticsNodalMarginal2016b?
TOX Tier 1 GE5 Reddy et al
TP53 Tier 1 GElohrDiscoveryPrioritizationSomatic2012a?, FErowhTp53DeletionLineage2011? Lohr et al 6,8,58,rossiCodingGenomeSplenic2012c?,tiacciPervasiveMutationsJAKSTAT2018b?
UBE2A Tier 1 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al reichelFlowSortingExome2015a?
WEE1 Tier 1 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al reichelFlowSortingExome2015a?
XPO1 Tier 1 GE59 Mareschal et al jardinRecurrentMutationsExportin2016a?
ZC3H12A Tier 1 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al
ZFP36L1 Tier 1 GE8 Morin et al 20,reichelFlowSortingExome2015a?
ZNF292 Tier 1 GE5 Reddy et al
ZNF608 Tier 1 GE21 Morin et al krysiakRecurrentSomaticMutations2017b?

Tier 2 DLBCL genes

179 total

Gene Summary First DLBCL study Other entities QC result
ABI3BP Tier 2 GE21 Morin et al PASS
ADAMTS1 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
AICDA Tier 2 GE36 Arthur et al
ANKRD12 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
ANKRD17 Tier 2 GE2 Zhang et al
ARID5B Tier 2 GE5 Reddy et al 27 PASS
ASXL3 Tier 2 GEalbuquerqueEnhancingKnowledgeDiscovery2017a? Albuquerque et al
ATR Tier 2 GE5 Reddy et al PASS
BCL11A Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al
BCOR Tier 2 GE 18,nadeuGenomicEpigenomicInsights2020b?
BCR Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
BIRC3 Tier 2 GE36 Arthur et al 6,dunsCharacterizationDLBCLPMBL2021b?,rossiAlterationBIRC3Multiple2011a?
BLK Tier 2 GE
BRINP3 Tier 2 GE5 Reddy et al PASS
BTBD3 Tier 2 GE2 Zhang et al
CADPS2 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
CASP8 Tier 2 GE5, FE60 Reddy et al
CD22 Tier 2 GE5 Reddy et al PASS
CD274 Tier 2 GE8 Morin et al
CD36 Tier 2 GE35 Pasqualucci et al
CD44 Tier 2 GE36 Arthur et al
CD74 Tier 2 GE36 Arthur et al
CDH9 Tier 2 GE21 Morin et al PASS
CEP164 Tier 2 GEalbuquerqueEnhancingKnowledgeDiscovery2017a? Albuquerque et al
CNOT2 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
CNTNAP5 Tier 2 GE21 Morin et al PASS
COQ7 Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al PASS
CPS1 Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
CRIP1 Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al PASS
DAZAP1 Tier 2 GE9 Pararajalingam et al
DDX10 Tier 2 GE2 Zhang et al
DHX16 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
DNAH5 Tier 2 GE21 Morin et al 18 PASS
DNM2 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
DNMT3B Tier 2 GEalbuquerqueEnhancingKnowledgeDiscovery2017a? Albuquerque et al
DOCK1 Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al PASS
DSG4 Tier 2 GE21 Morin et al PASS
EIF2AK3 Tier 2 GE
ERAP2 Tier 2 GEalbuquerqueEnhancingKnowledgeDiscovery2017a? Albuquerque et al
EZR Tier 2 GE 1
FAM102A Tier 2 GE
FANK1 Tier 2 GE
FAT2 Tier 2 GE8 Morin et al
FAT4 Tier 2 GE21 Morin et al 23,42 PASS
FCRL3 Tier 2 GE
FNBP1 Tier 2 GE
FOXC1 Tier 2 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al
FOXP1 Tier 2 GE5 Reddy et al PASS
FUBP1 Tier 2 GE5 Reddy et al PASS
GABRA1 Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
GABRA2 Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al
GOLGA5 Tier 2 GE5 Reddy et al PASS
GPC5 Tier 2 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al
GSG2 Tier 2 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al
H1FOO Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
HDAC7 Tier 2 GE21 Morin et al PASS
HIST1H2AG Tier 2 GE21 Morin et al 20,krysiakRecurrentSomaticMutations2017b?,rossiCodingGenomeSplenic2012c? PASS
HIST1H2AL Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
HIST1H2BO Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
HLA-DMA Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al
HNF1B Tier 2 GE35 Pasqualucci et al
HNRNPD Tier 2 GE5 Reddy et al
HNRNPH1 Tier 2 GE9, FE9, CE9 Pararajalingam et al
ID3 Tier 2 GE17, FErichterRecurrentMutationID32012a? Schmitz et al richterRecurrentMutationID32012a?,spinaGeneticsNodalMarginal2016b?
IFNGR1 Tier 2 GE21 Morin et al PASS
IGLL5 Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al 1,20,russler-germainMutationsAssociatedProgression2023b?
IKBKB Tier 2 GE5 Reddy et al rossiAlterationBIRC3Multiple2011a?,wienandGenomicAnalysesFlowsorted2019b? PASS
IKBKE Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
IL16 Tier 2 GE5 Reddy et al
IL6 Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al PASS
INO80 Tier 2 GE2 Zhang et al
IRF1 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
JAK1 Tier 2 GE2 Zhang et al mottokIntegrativeGenomicAnalysis2019b?
JAK3 Tier 2 GE2 Zhang et al
KCMF1 Tier 2 GE5 Reddy et al PASS
KLHL21 Tier 2 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al
KRTAP5-5 Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
LAMA5 Tier 2 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al
LAPTM5 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
LPP Tier 2 GE36 Arthur et al
LRP12 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
LYN Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al PASS
MAGT1 Tier 2 GE5 Reddy et al PASS
MALAT1 Tier 2 GE36 Arthur et al
MAP2K1 Tier 2 GE61 Shin et al louissaintPediatrictypeNodalFollicular2016a?
MCL1 Tier 2 GE5 Reddy et al 20,dunsCharacterizationDLBCLPMBL2021b? PASS
MECOM Tier 2 GE5 Reddy et al PASS
MET Tier 2 GE5 Reddy et al PASS
MIR155HG Tier 2 GE
MPDZ Tier 2 GE21 Morin et al reichelFlowSortingExome2015a? PASS
MSH6 Tier 2 GE5 Reddy et al PASS
MYBPC2 Tier 2 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al
MYO1E Tier 2 GE
MYOM2 Tier 2 GE35 Pasqualucci et al
NAV1 Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al
NCOA3 Tier 2 GE
NCOR2 Tier 2 GE 17,sarkozyMutationalLandscapeGray2021a?,spinaGeneticsNodalMarginal2016b?
NEAT1 Tier 2 GE36 Arthur et al
NF1 Tier 2 GE2 Zhang et al
NFKB1 Tier 2 GE
NLRC5 Tier 2 GE
NLRP5 Tier 2 GE21 Morin et al PASS
ODZ3 Tier 2 GE21 Morin et al PASS
OR6K3 Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
P2RX5 Tier 2 GE21 Morin et al PASS
PAPOLG Tier 2 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al
PASD1 Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
PASK Tier 2 GE21 Morin et al PASS
PAX5 Tier 2 GEpasqualucciHypermutationMultipleProtooncogenes2001a? Pasqualucci et al
PCBP1 Tier 2 GE 17
PCDHB11 Tier 2 GE21 Morin et al PASS
PCDHB6 Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
PCLO Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
PDGFC Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
PDS5B Tier 2 GE21 Morin et al hubschmannMutationalMechanismsShaping2021b? PASS
PIK3CD Tier 2 GE2 Zhang et al
PIK3R1 Tier 2 GE2 Zhang et al 20
PNPO Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
PPP1R9B Tier 2 GE
PRKCB Tier 2 GE21 Morin et al PASS
PRKDC Tier 2 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al hubschmannMutationalMechanismsShaping2021b?
PRPS1 Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al PASS
PTMA Tier 2 GE
PTPN1 Tier 2 GE gunawardanaRecurrentSomaticMutations2014c?
PTPN6 Tier 2 GE5 Reddy et al PASS
PTPRD Tier 2 GE spinaGeneticsNodalMarginal2016b?
RAC2 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
RAPGEF1 Tier 2 GE8 Morin et al
RCC Tier 2 GE
RFTN1 Tier 2 GE36 Arthur et al dunsCharacterizationDLBCLPMBL2021b?
RFXAP Tier 2 GE
RHEX Tier 2 GE
RHOH Tier 2 GEpasqualucciHypermutationMultipleProtooncogenes2001a? Pasqualucci et al
RUBCNL Tier 2 GE
S1PR1 Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al 9
SAMD9L Tier 2 GE21 Morin et al PASS
SEL1L3 Tier 2 GE
SEPTIN9 Tier 2 GE
SERPINA9 Tier 2 GE36 Arthur et al
SETD2 Tier 2 GE2 Zhang et al
SETD5 Tier 2 GE5 Reddy et al tiacciPervasiveMutationsJAKSTAT2018b? PASS
SIAH2 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al reichelFlowSortingExome2015a? PASS
SLC34A2 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
SLC38A8 Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
SLITRK6 Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
SMEK1 Tier 2 GE2 Zhang et al
SRPX Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
SRRM2 Tier 2 GE21 Morin et al russler-germainMutationsAssociatedProgression2023b? PASS
ST6GAL1 Tier 2 GE36 Arthur et al
STAT5B Tier 2 GE2 Zhang et al tiacciPervasiveMutationsJAKSTAT2018b?
SYN2 Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
SYPL1 Tier 2 GE21 Morin et al PASS
TAP1 Tier 2 GEschmitzGeneticsPathogenesisDiffuse2018a? Schmitz et al
TBC1D4 Tier 2 GE36 Arthur et al
TCL1A Tier 2 GE5 Reddy et al 13
TGFBR2 Tier 2 GE5 Reddy et al PASS
TIPARP Tier 2 GE5 Reddy et al PASS
TLR2 Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al 6 PASS
TMSL3 Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
TNF Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
TRAF3 Tier 2 GE35 Pasqualucci et al ottoGeneticLesionsTRAF32012a?,rossiAlterationBIRC3Multiple2011a?
TRAF6 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
TRIP12 Tier 2 GE
UBE2J1 Tier 2 GE
UBR5 Tier 2 GE2 Zhang et al 9
UHRF1BP1 Tier 2 GEalbuquerqueEnhancingKnowledgeDiscovery2017a? Albuquerque et al
UNC5B Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al PASS
UNC5C Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
UNC5D Tier 2 GElohrDiscoveryPrioritizationSomatic2012a? Lohr et al
USP7 Tier 2 GE36 Arthur et al 13
WDFY3 Tier 2 GE21 Morin et al PASS
WNK1 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al 18,29 PASS
XBP1 Tier 2 GE
YY1 Tier 2 GE5 Reddy et al PASS
ZCCHC7 Tier 2 GE36 Arthur et al
ZEB2 Tier 2 GE2 Zhang et al
ZFX Tier 2 GE5 Reddy et al PASS
ZNF217 Tier 2 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al reichelFlowSortingExome2015a? PASS
ZNF423 Tier 2 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al PASS

Tier 3 DLBCL genes

386 total

Gene Summary First DLBCL study Other entities QC result
ABCA3 Tier 3 GE2 Zhang et al 6
ABCA4 Tier 3 GE2 Zhang et al
ABCB1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
ACE Tier 3 GE2 Zhang et al 4
ACSM3 Tier 3 GE2 Zhang et al
ACSS2 Tier 3 GE2 Zhang et al
ACSS3 Tier 3 GE2 Zhang et al
ACTN1 Tier 3 GE2 Zhang et al
ADAM2 Tier 3 GE2 Zhang et al
ADAMTS15 Tier 3 GE2 Zhang et al
ADH7 Tier 3 GE2 Zhang et al
AFAP1L2 Tier 3 GE2 Zhang et al
AGA Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
AHR Tier 3 GE2 Zhang et al
AKAP9 Tier 3 GE2 Zhang et al
ALAS1 Tier 3 GE2 Zhang et al
ALDH1L2 Tier 3 GE2 Zhang et al
AMAC1 Tier 3 GE2 Zhang et al
AMIGO3 Tier 3 GE2 Zhang et al
AMPH Tier 3 GE2 Zhang et al
ANK2 Tier 3 GE2 Zhang et al 42
ANKRD44 Tier 3 GE2 Zhang et al
ANTXR1 Tier 3 GE2 Zhang et al
AP1G2 Tier 3 GE2 Zhang et al
APBB1 Tier 3 GE2 Zhang et al
APC Tier 3 GE2 Zhang et al
APMAP Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
APOA5 Tier 3 GE2 Zhang et al
APP Tier 3 GE2 Zhang et al
ARID1B Tier 3 GE5 Reddy et al FAIL
ATIC Tier 3 GE2 Zhang et al
ATP10A Tier 3 GE2 Zhang et al
ATP1A2 Tier 3 GE2 Zhang et al
ATP2A3 Tier 3 GE2 Zhang et al
ATP6V0A1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
B4GALNT2 Tier 3 GE2 Zhang et al
BAZ1A Tier 3 GE2 Zhang et al
BCAT2 Tier 3 GE2 Zhang et al
BLM Tier 3 GE2 Zhang et al
BMPR1A Tier 3 GE2 Zhang et al
BRCA1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
BRCA2 Tier 3 GE2 Zhang et al
BRD4 Tier 3 GE2 Zhang et al 4
BSCL2 Tier 3 GE2 Zhang et al
BTAF1 Tier 3 GE2 Zhang et al
C9 Tier 3 GE2 Zhang et al
CAD Tier 3 GE2 Zhang et al 4
CAPN5 Tier 3 GE2 Zhang et al
CAPN7 Tier 3 GE2 Zhang et al
CBLB Tier 3 GE5 Reddy et al FAIL
CBX3 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
CCDC132 Tier 3 GE2 Zhang et al
CCDC46 Tier 3 GE2 Zhang et al
CCDC97 Tier 3 GE2 Zhang et al
CCL4 Tier 3 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al FAIL
CCNF Tier 3 GE2 Zhang et al abateDistinctViralMutational2015a?
CDC123 Tier 3 GE2 Zhang et al
CDC73 Tier 3 GE5 Reddy et al 4 FAIL
CDH10 Tier 3 GE2 Zhang et al
CDH7 Tier 3 GE2 Zhang et al
CDH8 Tier 3 GE5 Reddy et al 42 FAIL
CDK3 Tier 3 GE2 Zhang et al
CDKN1A Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
CECR1 Tier 3 GE2 Zhang et al
CELSR2 Tier 3 GE2 Zhang et al
CGN Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
CHD1 Tier 3 GE5 Reddy et al FAIL
CHD3 Tier 3 GE2 Zhang et al
CHEK2 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
CHRM5 Tier 3 GE2 Zhang et al
CHST2 Tier 3 GE5 Reddy et al FAIL
CIC Tier 3 GE2 Zhang et al
CNGA4 Tier 3 GE2 Zhang et al
CNOT6 Tier 3 GE2 Zhang et al
CNP Tier 3 GE2 Zhang et al
CNTN6 Tier 3 GE2 Zhang et al
COL5A2 Tier 3 GE2 Zhang et al
CORO2A Tier 3 GE2 Zhang et al
CORO7 Tier 3 GE2 Zhang et al
CRELD2 Tier 3 GE2 Zhang et al
CRTC3 Tier 3 GE2 Zhang et al
CSNK1A1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
CSNK2A1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
CST7 Tier 3 GE2 Zhang et al
CTNNA3 Tier 3 GE2 Zhang et al
CYP24A1 Tier 3 GE2 Zhang et al
CYP2C18 Tier 3 GE2 Zhang et al
CYYR1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
DCAF6 Tier 3 GE5 Reddy et al FAIL
DDB1 Tier 3 GE2 Zhang et al
DGCR8 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
DHX33 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
DIAPH3 Tier 3 GE2 Zhang et al
DICER1 Tier 3 GE5 Reddy et al FAIL
DIP2B Tier 3 GE2 Zhang et al
DLGAP1 Tier 3 GE2 Zhang et al 4
DMXL1 Tier 3 GE2 Zhang et al
DNMT3A Tier 3 GE5 Reddy et al FAIL
DOCK2 Tier 3 GE2 Zhang et al
DOCK5 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
DOLK Tier 3 GE2 Zhang et al
DSC2 Tier 3 GE2 Zhang et al
DSCAML1 Tier 3 GE2 Zhang et al
DSG2 Tier 3 GE2 Zhang et al
DSP Tier 3 GE2 Zhang et al
DUOXA2 Tier 3 GE2 Zhang et al
DUPD1 Tier 3 GE2 Zhang et al
DYNC1H1 Tier 3 GE2 Zhang et al
DYNC1I1 Tier 3 GE2 Zhang et al
ECGF1 Tier 3 GE2 Zhang et al
ECT2L Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
EGFR Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
EPHA3 Tier 3 GE2 Zhang et al
EPHA5 Tier 3 GE2 Zhang et al
EPHA7 Tier 3 GE2 Zhang et al mottokIntegrativeGenomicAnalysis2019b?
ERBB3 Tier 3 GE2 Zhang et al
ERN2 Tier 3 GE2 Zhang et al
ETNPPL Tier 3 GE2 Zhang et al
EXTL3 Tier 3 GE2 Zhang et al
FAIM Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
FAM161A Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
FAM38B Tier 3 GE21 Morin et al FAIL
FAM62C Tier 3 GE2 Zhang et al
FANCD2 Tier 3 GE2 Zhang et al
FGD3 Tier 3 GE2 Zhang et al
FGFR1 Tier 3 GE2 Zhang et al
FIGN Tier 3 GE2 Zhang et al
FLNA Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
FLNC Tier 3 GE2 Zhang et al
FLT1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
FMO2 Tier 3 GE2 Zhang et al
FN1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
FNDC1 Tier 3 GE21 Morin et al FAIL
FRMPD1 Tier 3 GE2 Zhang et al
FUT5 Tier 3 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al FAIL
FZD1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
GABRG1 Tier 3 GE2 Zhang et al
GAK Tier 3 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al FAIL
GATA2 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
GATA3 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
GCN1L1 Tier 3 GE2 Zhang et al
GJA8 Tier 3 GE2 Zhang et al
GJB4 Tier 3 GE2 Zhang et al
GNAS Tier 3 GE5 Reddy et al FAIL
GOPC Tier 3 GE2 Zhang et al
GPD2 Tier 3 GE2 Zhang et al
GPR133 Tier 3 GE2 Zhang et al
GPR15 Tier 3 GE2 Zhang et al
GREM2 Tier 3 GE2 Zhang et al
GRIA2 Tier 3 GE2 Zhang et al
GRM5 Tier 3 GE2 Zhang et al
H6PD Tier 3 GE2 Zhang et al
HACE1 Tier 3 GE2 Zhang et al
HCK Tier 3 GE2 Zhang et al
HFE Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
HIPK3 Tier 3 GE2 Zhang et al
HIST1H4I Tier 3 GE2 Zhang et al
HK3 Tier 3 GE2 Zhang et al
HLA-DQA1 Tier 3 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al FAIL
HLA-DRB1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
HNRNPR Tier 3 GE2 Zhang et al
HRAS Tier 3 GE5 Reddy et al 18 FAIL
HSF2 Tier 3 GE2 Zhang et al
IDH1 Tier 3 GE2 Zhang et al
IER2 Tier 3 GE21 Morin et al FAIL
IL6ST Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
INSC Tier 3 GE2 Zhang et al
INTS6 Tier 3 GE2 Zhang et al
IQGAP1 Tier 3 GE2 Zhang et al
IQUB Tier 3 GE2 Zhang et al
ITGA2 Tier 3 GE2 Zhang et al
ITGA8 Tier 3 GE2 Zhang et al
ITGB3 Tier 3 GE2 Zhang et al
ITGB4 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
ITPR1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
JAG1 Tier 3 GE2 Zhang et al
JAKMIP2 Tier 3 GE2 Zhang et al
KCNA3 Tier 3 GE2 Zhang et al
KCNAB3 Tier 3 GE2 Zhang et al
KCNJ6 Tier 3 GE2 Zhang et al
KCNT2 Tier 3 GE2 Zhang et al
KDR Tier 3 GE2 Zhang et al
KIF21B Tier 3 GE2 Zhang et al
KIT Tier 3 GE2 Zhang et al
KITLG Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
KLB Tier 3 GE2 Zhang et al
KLC3 Tier 3 GE2 Zhang et al
KLF4 Tier 3 GE2 Zhang et al
KLRC4 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
KRT6A Tier 3 GE2 Zhang et al
LEPR Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
LEPREL1 Tier 3 GE2 Zhang et al
LIFR Tier 3 GE2 Zhang et al
LILRA2 Tier 3 GE2 Zhang et al
LIN54 Tier 3 GE5 Reddy et al FAIL
LIN7C Tier 3 GE2 Zhang et al
LPHN2 Tier 3 GE2 Zhang et al
LRAP Tier 3 GE2 Zhang et al
LRIG3 Tier 3 GE2 Zhang et al
LRP1 Tier 3 GE2 Zhang et al
LRP10 Tier 3 GE2 Zhang et al
LRP1B Tier 3 GE2 Zhang et al spinaGeneticsNodalMarginal2016b?
LRP3 Tier 3 GE2 Zhang et al
LYST Tier 3 GE2 Zhang et al
MAP2K3 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
MAP4K4 Tier 3 GE5 Reddy et al FAIL
MARCHF7 Tier 3 GE2 Zhang et al
MARK1 Tier 3 GE5 Reddy et al FAIL
MBL2 Tier 3 GE2 Zhang et al
MCM8 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
MED13L Tier 3 GE2 Zhang et al
MIB1 Tier 3 GE2 Zhang et al
MLH1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
MMEL1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
MN1 Tier 3 GE2 Zhang et al
MORC2 Tier 3 GE2 Zhang et al
MPL Tier 3 GE2 Zhang et al
MSH2 Tier 3 GE5 Reddy et al FAIL
MSN Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
MTMR3 Tier 3 GE2 Zhang et al
MYB Tier 3 GE5 Reddy et al 1 FAIL
MYL7 Tier 3 GE2 Zhang et al
MYO5C Tier 3 GE2 Zhang et al
MYRIP Tier 3 GE2 Zhang et al
NANOG Tier 3 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al FAIL
NCOR1 Tier 3 GE5 Reddy et al FAIL
NDUFS1 Tier 3 GE2 Zhang et al
NELL2 Tier 3 GE2 Zhang et al
NFIB Tier 3 GE2 Zhang et al
NFKB2 Tier 3 GE5 Reddy et al mottokIntegrativeGenomicAnalysis2019b? FAIL
NFX1 Tier 3 GE2 Zhang et al
NGFR Tier 3 GE2 Zhang et al
NIPBL Tier 3 GE2 Zhang et al
NLGN2 Tier 3 GE2 Zhang et al
NLRP7 Tier 3 GE2 Zhang et al
NLRP8 Tier 3 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al FAIL
NOTCH3 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
NPHP1 Tier 3 GE2 Zhang et al
NPY2R Tier 3 GE2 Zhang et al
NR2F2 Tier 3 GEhubschmannMutationalMechanismsShaping2021b? Hubschmann et al FAIL
NRXN2 Tier 3 GE2 Zhang et al 4
NSD1 Tier 3 GE2 Zhang et al
NSD2 Tier 3 GE2 Zhang et al 6
NUP153 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
ONECUT1 Tier 3 GE2 Zhang et al
PABPC1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
PADI1 Tier 3 GE2 Zhang et al
PAPPA2 Tier 3 GE2 Zhang et al
PBX1 Tier 3 GE2 Zhang et al
PCCB Tier 3 GE2 Zhang et al
PCDE1C Tier 3 GE2 Zhang et al
PCDH7 Tier 3 GE2 Zhang et al
PCDHB1 Tier 3 GE2 Zhang et al
PCDHB15 Tier 3 GE2 Zhang et al
PCDHB3 Tier 3 GE2 Zhang et al
PCDHB5 Tier 3 GE2 Zhang et al
PCDHGA2 Tier 3 GE2 Zhang et al
PDE1C Tier 3 GE2 Zhang et al
PDE4DIP Tier 3 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al FAIL
PDGFRA Tier 3 GE2 Zhang et al
PDGFRB Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
PDIA2 Tier 3 GE2 Zhang et al
PDZRN3 Tier 3 GE2 Zhang et al 20
PDZRN4 Tier 3 GE2 Zhang et al
PFN1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
PGR Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
PHF6 Tier 3 GE5 Reddy et al 29 FAIL
PKD1 Tier 3 GE21 Morin et al FAIL
PLA2G4B Tier 3 GE2 Zhang et al
PLCB4 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
PLCG2 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al 20
PLEKHA7 Tier 3 GE2 Zhang et al
PNLIPRP1 Tier 3 GE2 Zhang et al
PNPT1 Tier 3 GE2 Zhang et al
POGZ Tier 3 GE21 Morin et al FAIL
POLD3 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
POLE Tier 3 GE2 Zhang et al
POLQ Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
PPARGC1A Tier 3 GE2 Zhang et al
PPP2R2B Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
PPWD1 Tier 3 GE2 Zhang et al
PRDM16 Tier 3 GE2 Zhang et al
PRKCB1 Tier 3 GE2 Zhang et al
PRKCQ Tier 3 GE2 Zhang et al
PROS1 Tier 3 GE2 Zhang et al
PRSS7 Tier 3 GE2 Zhang et al
PTCH1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
PTPN14 Tier 3 GE2 Zhang et al
PTPN23 Tier 3 GE21 Morin et al FAIL
PTPRF Tier 3 GE2 Zhang et al
PTPRK Tier 3 GE5 Reddy et al FAIL
PTPRT Tier 3 GE2 Zhang et al
PXK Tier 3 GE2 Zhang et al
RAB3GAP1 Tier 3 GE2 Zhang et al
RAD9A Tier 3 GEchapuyMolecularSubtypesDiffuse2018b? Chapuy et al FAIL
RAF1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al 18
RAPGEF2 Tier 3 GE2 Zhang et al
RAPGEF3 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
RARA Tier 3 GE5 Reddy et al FAIL
RBM15B Tier 3 GE2 Zhang et al
RECQL4 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
RELN Tier 3 GE2 Zhang et al sarkozyMutationalLandscapeGray2021a?
RET Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al 4
RFC1 Tier 3 GE2 Zhang et al
RGS1 Tier 3 GE2 Zhang et al mottokIntegrativeGenomicAnalysis2019b?
RHPN2 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
RIF1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
RIMS4 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
ROR2 Tier 3 GE2 Zhang et al
RPTOR Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
RSL1D1 Tier 3 GE2 Zhang et al
RUNDC1 Tier 3 GE2 Zhang et al
RUNX1 Tier 3 GE5 Reddy et al FAIL
RYR1 Tier 3 GE2 Zhang et al
SAPS3 Tier 3 GE2 Zhang et al
SARM1 Tier 3 GE21 Morin et al FAIL
SCYL1 Tier 3 GE2 Zhang et al
SEMA3A Tier 3 GE2 Zhang et al
SEMA3D Tier 3 GE2 Zhang et al
SEMA5A Tier 3 GE2 Zhang et al
SERINC2 Tier 3 GE2 Zhang et al
SH3PXD2B Tier 3 GE2 Zhang et al
SHMT2 Tier 3 GE2 Zhang et al
SIGLEC10 Tier 3 GE2 Zhang et al
SLC16A7 Tier 3 GE2 Zhang et al
SLC16A8 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
SLC4A8 Tier 3 GE2 Zhang et al
SLC5A1 Tier 3 GE2 Zhang et al
SLC9A5 Tier 3 GE2 Zhang et al
SMO Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
SOS2 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
SOX6 Tier 3 GE2 Zhang et al
SPEG Tier 3 GE2 Zhang et al
SPTBN1 Tier 3 GE2 Zhang et al
ST8SIA3 Tier 3 GE2 Zhang et al
SULF2 Tier 3 GE2 Zhang et al
SYK Tier 3 GE5 Reddy et al FAIL
TAF1L Tier 3 GE2 Zhang et al
TAF4B Tier 3 GE2 Zhang et al
TECRL Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
THBS4 Tier 3 GE2 Zhang et al
TIMM50 Tier 3 GE2 Zhang et al
TLN1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
TLN2 Tier 3 GE2 Zhang et al
TLR4 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
TMC1 Tier 3 GE2 Zhang et al
TMEM161A Tier 3 GE2 Zhang et al
TMEM16E Tier 3 GE2 Zhang et al
TMEM63A Tier 3 GE2 Zhang et al
TNPO1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
TPR Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
TPRKB Tier 3 GE2 Zhang et al
TRIM37 Tier 3 GE2 Zhang et al
TRIP11 Tier 3 GE2 Zhang et al reichelFlowSortingExome2015a?
TRRAP Tier 3 GE2 Zhang et al rossiCodingGenomeSplenic2012c?
TSC2 Tier 3 GE2 Zhang et al
TSHZ2 Tier 3 GE2 Zhang et al
TYRO3 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
UBXN11 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
UBXN2B Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
UHRF1BP1L Tier 3 GE2 Zhang et al
UNC13B Tier 3 GE2 Zhang et al
UQCRC1 Tier 3 GE2 Zhang et al
VANGL1 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
VPS13A Tier 3 GE2 Zhang et al
WAC Tier 3 GE5 Reddy et al rossiCodingGenomeSplenic2012c? FAIL
WDR65 Tier 3 GE2 Zhang et al
WDR66 Tier 3 GE2 Zhang et al
WDR67 Tier 3 GE2 Zhang et al
WIF1 Tier 3 GE2 Zhang et al
WNK4 Tier 3 GE2 Zhang et al
WT1 Tier 3 GE2 Zhang et al
XDH Tier 3 GE2 Zhang et al
ZBTB7A Tier 3 GE5 Reddy et al burkhardtClinicalRelevanceMolecular2022b? FAIL
ZFAT Tier 3 GE5 Reddy et al FAIL
ZIC4 Tier 3 GE2 Zhang et al
ZMYM4 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
ZNF354A Tier 3 GE2 Zhang et al
ZNF366 Tier 3 GE2 Zhang et al
ZNF439 Tier 3 GE2 Zhang et al
ZNF474 Tier 3 GE2 Zhang et al
ZNF700 Tier 3 GE2 Zhang et al
ZNF790 Tier 3 GE2 Zhang et al
ZNF814 Tier 3 GEfanComprehensiveCharacterizationDriver2020b? Fan et al
ZNF91 Tier 3 GE2 Zhang et al
ZP1 Tier 3 GE2 Zhang et al

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