EDNRB

Relevance tier by entity

Entity Tier Description
BL 2 relevance in BL not firmly established

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
BL GAMBL genomes+capture 1.62
BL Thomas cohort NA
BL Panea cohort NA

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 3.877 0.000
DLBCL No No 0.482 0.000
FL No No 2.521 28.057

[!NOTE] First described in BL in 2022 by Burkhardt B

View coding variants in ProteinPaint hg19 or hg38

image

View all variants in GenomePaint hg19 or hg38

image ## EDNRB Expression image