Table of Contents
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
3 | Mutations are unlikely to be relevant to DLBCL |
 |
2 | Role of EPHA7 mutations in PMBL requires confirmation |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| BL | GAMBL Exome | 4.598 |
| BL | GAMBL Genome | 1.544 |
| DLBCL | GAMBL Exome | 2.803 |
| DLBCL | GAMBL Genome | 3.383 |
| FL | GAMBL Exome | 2.292 |
| MCL | GAMBL Genome | 1.754 |
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References
1.
Mottok A, Hung SS, Chavez EA, Woolcock B,
Telenius A, Chong LC, Meissner B, Nakamura H, Rushton C, Viganò E,
Sarkozy C, Gascoyne RD, Connors JM, Ben-Neriah S, Mungall A, Marra MA,
Siebert R, Scott DW, Savage KJ, Steidl C. Integrative genomic
analysis identifies key pathogenic mechanisms in primary mediastinal
large B-cell lymphoma. Blood. 2019 Sep
5;134(10):802–813.