[FBXO11]
Mutation tier
| Entity | Tier |
|---|---|
| BL | 1 |
| DLBCL | 1 |
Mutation incidence
| Entity | study | frequency (%) |
|---|---|---|
| BL | GAMBL genomes+capture | 23.79 |
| BL | Thomas cohort | 21.60 |
| BL | Panea cohort | 15.80 |
| DLBCL | GAMBL genomes | 4.10 |
| DLBCL | Schmitz cohort | 2.10 |
| DLBCL | Reddy cohort | 2.10 |
| DLBCL | Chapuy cohort | 2.60 |
Mutation pattern
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | Yes | 14.801 | 114.063 |
| DLBCL | No | Yes | 2.464 | 39.449 |
| FL | No | No | 8.837 | 0.000 |
[!NOTE] First described in BL in 2023 by Thomas N
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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