Origins of FL genes
Tier 1 FL genes
54 total
Tier 2 FL genes
59 total
Tier 3 FL genes
0 total
| Gene | Summary | First FL study | Other entities | QC result |
|---|
References
1.
Dreval K, Hilton LK, Cruz M, Shaalan H,
Ben-Neriah S, Boyle M, Collinge B, Coyle KM, Duns G, Farinha P, Grande
BM, Meissner B, Pararajalingam P, Rushton CK, Slack GW, Wong J, Mungall
AJ, Marra MA, Connors JM, Steidl C, Scott DW, Morin RD. Genetic
subdivisions of follicular lymphoma defined by distinct coding and
noncoding mutation patterns. Blood. 2023 Aug 10;142(6):561–573. PMCID:
PMC10644066
2.
Lohr
JG, Stojanov P, Lawrence MS, Auclair D, Chapuy B, Sougnez C,
Cruz-Gordillo P, Knoechel B, Asmann YW, Slager SL, Novak AJ, Dogan A,
Ansell SM, Link BK, Zou L, Gould J, Saksena G, Stransky N,
Rangel-Escareño C, Fernandez-Lopez JC, Hidalgo-Miranda A,
Melendez-Zajgla J, Hernández-Lemus E, Schwarz-Cruz y Celis A,
Imaz-Rosshandler I, Ojesina AI, Jung J, Pedamallu CS, Lander ES,
Habermann TM, Cerhan JR, Shipp MA, Getz G, Golub TR. Discovery and
prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by
whole-exome sequencing. Proc Natl Acad Sci U S A. 2012 Mar
6;109(10):3879–3884. PMCID: PMC3309757
3.
Wienand K, Chapuy B, Stewart C, Dunford AJ, Wu
D, Kim J, Kamburov A, Wood TR, Cader FZ, Ducar MD, Thorner AR, Nag A,
Heubeck AT, Buonopane MJ, Redd RA, Bojarczuk K, Lawton LN, Armand P,
Rodig SJ, Fromm JR, Getz G, Shipp MA. Genomic analyses of flow-sorted
Hodgkin Reed-Sternberg cells reveal complementary
mechanisms of immune evasion. Blood Adv. 2019 Dec 10;3(23):4065–4080.
PMCID: PMC6963251
4.
Krysiak K, Gomez F, White BS, Matlock M, Miller
CA, Trani L, Fronick CC, Fulton RS, Kreisel F, Cashen AF, Carson KR,
Berrien-Elliott MM, Bartlett NL, Griffith M, Griffith OL, Fehniger TA.
Recurrent somatic mutations affecting B-cell
receptor signaling pathway genes in follicular lymphoma. Blood. 2017 Jan
26;129(4):473–483. PMCID: PMC5270390
5.
Barisic D, Chin CR, Meydan C, Teater M, Tsialta
I, Mlynarczyk C, Chadburn A, Wang X, Sarkozy M, Xia M, Carson SE,
Raggiri S, Debek S, Pelzer B, Durmaz C, Deng Q, Lakra P, Rivas M, Steidl
C, Scott DW, Weng AP, Mason CE, Green MR, Melnick A. ARID1A
orchestrates SWI/SNF-mediated
sequential binding of transcription factors with ARID1A
loss driving pre-memory B cell fate and
lymphomagenesis. Cancer Cell. 2024 Apr 8;42(4):583–604.e11.
6.
Love
C, Sun Z, Jima D, Li G, Zhang J, Miles R, Richards KL, Dunphy CH, Choi
WWL, Srivastava G, Lugar PL, Rizzieri DA, Lagoo AS, Bernal-Mizrachi L,
Mann KP, Flowers CR, Naresh KN, Evens AM, Chadburn A, Gordon LI, Czader
MB, Gill JI, Hsi ED, Greenough A, Moffitt AB, McKinney M, Banerjee A,
Grubor V, Levy S, Dunson DB, Dave SS. The genetic landscape of mutations
in Burkitt lymphoma. Nat Genet. 2012 Dec;44(12):1321–1325.
PMCID: PMC3674561
7.
Rossi D, Trifonov V, Fangazio M, Bruscaggin A,
Rasi S, Spina V, Monti S, Vaisitti T, Arruga F, Famà R, Ciardullo C,
Greco M, Cresta S, Piranda D, Holmes A, Fabbri G, Messina M, Rinaldi A,
Wang J, Agostinelli C, Piccaluga PP, Lucioni M, Tabbò F, Serra R,
Franceschetti S, Deambrogi C, Daniele G, Gattei V, Marasca R, Facchetti
F, Arcaini L, Inghirami G, Bertoni F, Pileri SA, Deaglio S, Foà R,
Dalla-Favera R, Pasqualucci L, Rabadan R, Gaidano G. The coding genome
of splenic marginal zone lymphoma: Activation of NOTCH2 and
other pathways regulating marginal zone development. J Exp Med. 2012 Aug
27;209(9):1537–1551. PMCID: PMC3428941
8.
Zhang J, Grubor V, Love CL, Banerjee A,
Richards KL, Mieczkowski PA, Dunphy C, Choi W, Au WY, Srivastava G,
Lugar PL, Rizzieri DA, Lagoo AS, Bernal-Mizrachi L, Mann KP, Flowers C,
Naresh K, Evens A, Gordon LI, Czader M, Gill JI, Hsi ED, Liu Q, Fan A,
Walsh K, Jima D, Smith LL, Johnson AJ, Byrd JC, Luftig MA, Ni T, Zhu J,
Chadburn A, Levy S, Dunson D, Dave SS. Genetic heterogeneity of diffuse
large B-cell lymphoma. Proceedings of the
National Academy of Sciences of the United States of America.
2013;110:1398–1403. PMCID: PMC3557051
9.
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins
L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF, Richter J, Bernhart
SH, Efeyan A, Iqbal S, Matthews J, Clear A, Guerra-Assunção JA, Bödör C,
Quentmeier H, Mansbridge C, Johnson P, Davies A, Strefford JC, Packham
G, Barrans S, Jack A, Du MQ, Calaminici M, Lister TA, Auer R, Montoto S,
Gribben JG, Siebert R, Chelala C, Zoncu R, Sabatini DM, Fitzgibbon J.
Recurrent mTORC1-activating RRAGC mutations
in follicular lymphoma. Nat Genet. 2016 Feb;48(2):183–188. PMCID: PMC4731318
10.
Morin RD, Mendez-Lago M, Mungall AJ, Goya R,
Mungall KL, Corbett RD, Johnson NA, Severson TM, Chiu R, Field M,
Jackman S, Krzywinski M, Scott DW, Trinh DL, Tamura-Wells J, Li S, Firme
MR, Rogic S, Griffith M, Chan S, Yakovenko O, Meyer IM, Zhao EY, Smailus
D, Moksa M, Chittaranjan S, Rimsza L, Brooks-Wilson A, Spinelli JJ,
Ben-Neriah S, Meissner B, Woolcock B, Boyle M, McDonald H, Tam A, Zhao
Y, Delaney A, Zeng T, Tse K, Butterfield Y, Birol I, Holt R, Schein J,
Horsman DE, Moore R, Jones SJM, Connors JM, Hirst M, Gascoyne RD, Marra
MA. Frequent mutation of histone-modifying genes in
non-Hodgkin lymphoma. Nature. 2011 Jul
27;476(7360):298–303. PMCID: PMC3210554
11.
Challa-Malladi M, Lieu YK, Califano O, Holmes
AB, Bhagat G, Murty VV, Dominguez-Sola D, Pasqualucci L, Dalla-Favera R.
Combined genetic inactivation of Β2-Microglobulin and
CD58 reveals frequent escape from immune recognition in
diffuse large B cell lymphoma. Cancer Cell. 2011 Dec
13;20(6):728–740. PMCID: PMC3660995
12.
Pararajalingam P, Coyle KM, Arthur SE, Thomas
N, Alcaide M, Meissner B, Boyle M, Qureshi Q, Grande BM, Rushton C,
Slack GW, Mungall AJ, Tam CS, Agarwal R, Dawson SJ, Lenz G,
Balasubramanian S, Gascoyne RD, Steidl C, Connors J, Villa D, Audas TE,
Marra MA, Johnson NA, Scott DW, Morin RD. Coding and noncoding drivers
of mantle cell lymphoma identified through exome and genome sequencing.
Blood. 2020 Jul 30;136(5):572–584. PMCID: PMC7440974
13.
Reichel J, Chadburn A, Rubinstein PG,
Giulino-Roth L, Tam W, Liu Y, Gaiolla R, Eng K, Brody J, Inghirami G,
Carlo-Stella C, Santoro A, Rahal D, Totonchy J, Elemento O, Cesarman E,
Roshal M. Flow
sorting and exome sequencing reveal the oncogenome of primary
Hodgkin and Reed-Sternberg cells. Blood.
2015 Feb 12;125(7):1061–1072.
14.
Russler-Germain DA, Krysiak K, Ramirez CA,
Mosior M, Watkins MP, Gomez F, Skidmore ZL, Trani L, Gao F, Geyer S,
Cashen A, Mehta-Shah N, Kahl B, Bartlett N, Alderuccio J, Lossos I,
Ondrejka S, Hsi E, Martin P, Leonard J, Griffith M, Griffith O, Fehniger
T. Mutations
associated with progression in follicular lymphoma predict inferior
outcomes at diagnosis: Alliance A151303. Blood
Advances. 2023;7:5524–5539.
15.
Xia
M, David L, Teater M, Gutierrez J, Wang X, Meydan C, Lytle A, Slack GW,
Scott DW, Morin RD, Onder O, Elenitoba-Johnson KSJ, Zamponi N,
Cerchietti L, Lu T, Philippar U, Fontan L, Wu H, Melnick AM. BCL10
Mutations Define Distinct Dependencies Guiding Precision Therapy
for DLBCL. Cancer Discov. 2022 Aug 5;12(8):1922–1941.
PMCID: PMC9357155
16.
Spina V, Khiabanian H, Messina M, Monti S,
Cascione L, Bruscaggin A, Spaccarotella E, Holmes AB, Arcaini L, Lucioni
M, Tabbò F, Zairis S, Diop F, Cerri M, Chiaretti S, Marasca R, Ponzoni
M, Deaglio S, Ramponi A, Tiacci E, Pasqualucci L, Paulli M, Falini B,
Inghirami G, Bertoni F, Foà R, Rabadan R, Gaidano G, Rossi D. The
genetics of nodal marginal zone lymphoma. Blood. 2016 Sep
8;128(10):1362–1373. PMCID: PMC5016706
17.
Burkhardt B, Michgehl U, Rohde J, Erdmann T,
Berning P, Reutter K, Rohde M, Borkhardt A, Burmeister T, Dave S,
Tzankov A, Dugas M, Sandmann S, Fend F, Finger J, Mueller S, Gökbuget N,
Haferlach T, Kern W, Hartmann W, Klapper W, Oschlies I, Richter J,
Kontny U, Lutz M, Maecker-Kolhoff B, Ott G, Rosenwald A, Siebert R, von
Stackelberg A, Strahm B, Woessmann W, Zimmermann M, Zapukhlyak M, Grau
M, Lenz G. Clinical relevance of molecular characteristics in
Burkitt lymphoma differs according to age. Nat Commun. 2022
Jul 6;13(1):3881. PMCID: PMC9259584
18.
Sarkozy C, Hung SS, Chavez EA, Duns G, Takata
K, Chong LC, Aoki T, Jiang A, Miyata-Takata T, Telenius A, Slack GW,
Molina TJ, Ben-Neriah S, Farinha P, Dartigues P, Damotte D, Mottok A,
Salles GA, Casasnovas RO, Savage KJ, Laurent C, Scott DW,
Traverse-Glehen A, Steidl C. Mutational landscape of
gray zone lymphoma. Blood. 2021 Apr 1;137(13):1765–1776.
19.
Tanaka S, Louie DC, Kant JA, Reed JC. Frequent incidence of
somatic mutations in translocated BCL2 oncogenes of
non-Hodgkin’s lymphomas. Blood. 1992 Jan
1;79(1):229–237.
20.
Mascle X, Albagli O, Lemercier C. Point mutations in
BCL6 DNA-binding domain reveal distinct
roles for the six zinc fingers. Biochem Biophys Res Commun. 2003 Jan
10;300(2):391–396.
21.
Baliñas-Gavira C, Rodríguez MI, Andrades Á,
Cuadros M, Álvarez-Pérez J, Álvarez-Prado ÁF, Yébenes VG de,
Sanchez-Hernandez S, Fernández-Vigo E, Muñoz J, Martín F, Ramiro A,
Martinez-Climent J, Medina P. Frequent mutations in
the amino-terminal domain of BCL7A impair its tumor
suppressor role in DLBCL. Leukemia. 2020;1–14.
22.
Grande BM, Gerhard DS, Jiang A, Griner NB,
Abramson JS, Alexander TB, Allen H, Ayers LW, Bethony JM, Bhatia K,
Bowen J, Casper C, Choi JK, Culibrk L, Davidsen TM, Dyer MA,
Gastier-Foster JM, Gesuwan P, Greiner TC, Gross TG, Hanf B, Harris NL,
He Y, Irvin JD, Jaffe ES, Jones SJM, Kerchan P, Knoetze N, Leal FE,
Lichtenberg TM, Ma Y, Martin JP, Martin MR, Mbulaiteye SM, Mullighan CG,
Mungall AJ, Namirembe C, Novik K, Noy A, Ogwang MD, Omoding A, Orem J,
Reynolds SJ, Rushton CK, Sandlund JT, Schmitz R, Taylor C, Wilson WH,
Wright GW, Zhao EY, Marra MA, Morin RD, Staudt LM. Genome-wide discovery
of somatic coding and noncoding mutations in pediatric endemic and
sporadic Burkitt lymphoma. Blood. 2019;133(12):1313–1324.
PMCID: PMC6428665
23.
Hu
N, Wang F, Sun T, Xu Z, Zhang J, Bernard D, Xu S, Wang S, Kaminski M,
Devata S, Phillips T, Malek SN. Follicular Lymphoma-associated BTK Mutations are
Inactivating Resulting in Augmented AKT
Activation. Clin Cancer Res. 2021 Apr 15;27(8):2301–2313. PMCID:
PMC8046715
24.
Albuquerque MA, Grande BM, Ritch EJ,
Pararajalingam P, Jessa S, Krzywinski M, Grewal JK, Shah SP, Boutros PC,
Morin RD. Enhancing knowledge discovery from cancer genomics data with
Galaxy. Gigascience. 2017 May 1;6(5):1–13. PMCID: PMC5437943
25.
Lenz G, Davis RE, Ngo VN, Lam L, George TC,
Wright GW, Dave SS, Zhao H, Xu W, Rosenwald A, Ott G, Müller-Hermelink
HK, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J,
Smeland EB, Fisher RI, Chan WC, Staudt LM. Oncogenic
CARD11 mutations in human diffuse large B cell
lymphoma. Science. 2008 Mar;319(5870):1676–1679.
26.
Wu
C, de Miranda NF, Chen L, Wasik AM, Mansouri L, Jurczak W, Galazka K,
Dlugosz-Danecka M, Machaczka M, Zhang H, Peng R, Morin RD, Rosenquist R,
Sander B, Pan-Hammarström Q. Genetic heterogeneity in primary and
relapsed mantle cell lymphomas: Impact of recurrent
CARD11 mutations. Oncotarget. 2016 Jun
21;7(25):38180–38190. PMCID: PMC5122381
27.
Yan
Q, Huang Y, Watkins AJ, Kocialkowski S, Zeng N, Hamoudi RA, Isaacson PG,
de Leval L, Wotherspoon A, Du MQ. BCR and TLR
signaling pathways are recurrently targeted by genetic changes in
splenic marginal zone lymphomas. Haematologica. 2012 Apr;97(4):595–598.
PMCID: PMC3347666
28.
Schmitz R, Young RM, Ceribelli M, Jhavar S,
Xiao W, Zhang M, Wright G, Shaffer AL, Hodson DJ, Buras E, Liu X, Powell
J, Yang Y, Xu W, Zhao H, Kohlhammer H, Rosenwald A, Kluin P,
Müller-Hermelink HK, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E,
Jaffe ES, Delabie J, Smeland EB, Ogwang MD, Reynolds SJ, Fisher RI,
Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Pittaluga S,
Wilson W, Waldmann TA, Rowe M, Mbulaiteye SM, Rickinson AB, Staudt LM.
Burkitt lymphoma pathogenesis and therapeutic targets from structural
and functional genomics. Nature. 2012 Oct 4;490(7418):116–120. PMCID: PMC3609867
29.
Desch AK, Hartung K, Botzen A, Brobeil A,
Rummel M, Kurch L, Georgi T, Jox T, Bielack S, Burdach S, Classen CF,
Claviez A, Debatin KM, Ebinger M, Eggert A, Faber J, Flotho C, Frühwald
M, Graf N, Jorch N, Kontny U, Kramm C, Kulozik A, Kühr J, Sykora KW,
Metzler M, Müller HL, Nathrath M, Nüßlein T, Paulussen M, Pekrun A,
Reinhardt D, Reinhard H, Rössig C, Sauerbrey A, Schlegel PG, Schneider
DT, Scheurlen W, Schweigerer L, Simon T, Suttorp M, Vorwerk P, Schmitz
R, Kluge R, Mauz-Körholz C, Körholz D, Gattenlöhner S, Bräuninger A. Genotyping circulating
tumor DNA of pediatric Hodgkin lymphoma.
Leukemia. 2020 Jan;34(1):151–166.
30.
Jallades L, Baseggio L, Sujobert P, Huet S,
Chabane K, Callet-Bauchu E, Verney A, Hayette S, Desvignes JP, Salgado
D, Levy N, Béroud C, Felman P, Berger F, Magaud JP, Genestier L, Salles
G, Traverse-Glehen A. Exome sequencing identifies recurrent
BCOR alterations and the absence of KLF2,
TNFAIP3 and MYD88 mutations in splenic diffuse
red pulp small B-cell lymphoma.
Haematologica. 2017 Oct;102(10):1758–1766. PMCID: PMC5622860
31.
Richter J, Schlesner M, Hoffmann S, Kreuz M,
Leich E, Burkhardt B, Rosolowski M, Ammerpohl O, Wagener R, Bernhart SH,
Lenze D, Szczepanowski M, Paulsen M, Lipinski S, Russell RB, Adam-Klages
S, Apic G, Claviez A, Hasenclever D, Hovestadt V, Hornig N, Korbel JO,
Kube D, Langenberger D, Lawerenz C, Lisfeld J, Meyer K, Picelli S,
Pischimarov J, Radlwimmer B, Rausch T, Rohde M, Schilhabel M, Scholtysik
R, Spang R, Trautmann H, Zenz T, Borkhardt A, Drexler HG, Möller P,
MacLeod RAF, Pott C, Schreiber S, Trümper L, Loeffler M, Stadler PF,
Lichter P, Eils R, Küppers R, Hummel M, Klapper W, Rosenstiel P,
Rosenwald A, Brors B, Siebert R, ICGC MMML-Seq Project. Recurrent mutation of the
ID3 gene in Burkitt lymphoma identified by
integrated genome, exome and transcriptome sequencing. Nat Genet.
2012 Dec;44(12):1316–1320.
32.
Duns G, Viganò E, Ennishi D, Sarkozy C, Hung
SS, Chavez E, Takata K, Rushton C, Jiang A, Ben-Neriah S, Woolcock BW,
Slack GW, Hsi ED, Craig JW, Hilton LK, Shah SP, Farinha P, Mottok A,
Gascoyne RD, Morin RD, Savage KJ, Scott DW, Steidl C. Characterization of
DLBCL with a PMBL gene expression
signature. Blood. 2021 Jul 15;138(2):136–148.
33.
Morin RD, Mungall K, Pleasance E, Mungall AJ,
Goya R, Huff RD, Scott DW, Ding J, Roth A, Chiu R, Corbett RD, Chan FC,
Mendez-Lago M, Trinh DL, Bolger-Munro M, Taylor G, Hadj Khodabakhshi A,
Ben-Neriah S, Pon J, Meissner B, Woolcock B, Farnoud N, Rogic S, Lim EL,
Johnson NA, Shah S, Jones S, Steidl C, Holt R, Birol I, Moore R, Connors
JM, Gascoyne RD, Marra MA. Mutational and structural analysis of diffuse
large B-cell lymphoma using whole-genome
sequencing. Blood. 2013 Aug 15;122(7):1256–1265. PMCID: PMC3744992
34.
Panea R, Love C, Shingleton JR, Reddy A, Bailey
J, Moormann A, Otieno J, Ong’echa J, Oduor C, Schroêder K, Masalu N,
Chao N, Agajanian M, Major M, Fedoriw Y, Richards K, Rymkiewicz G, Miles
R, Alobeid B, Bhagat G, Flowers C, Ondrejka S, Hsi E, Choi W, Au-Yeung
R, Hartmann W, Lenz G, Meyerson H, Lin YY, Zhuang Y, Luftig M, Waldrop
A, Dave T, Thakkar D, Sahay H, Li G, Palus B, Seshadri V, Kim S,
Gascoyne R, Levy S, Mukhopadhyay M, Dunson D, Dave S. The whole genome
landscape of Burkitt lymphoma subtypes. Blood. 2019;
35.
Pasqualucci L, Dominguez-Sola D, Chiarenza A,
Fabbri G, Grunn A, Trifonov V, Kasper LH, Lerach S, Tang H, Ma J, Rossi
D, Chadburn A, Murty VV, Mullighan CG, Gaidano G, Rabadan R, Brindle PK,
Dalla-Favera R. Inactivating mutations of acetyltransferase genes in
B-cell lymphoma. Nature. 2011 Mar
10;471(7337):189–195. PMCID: PMC3271441
36.
Parry M, Rose-Zerilli MJJ, Gibson J, Ennis S,
Walewska R, Forster J, Parker H, Davis Z, Gardiner A, Collins A, Oscier
DG, Strefford JC. Whole exome sequencing identifies novel recurrently
mutated genes in patients with splenic marginal zone lymphoma. PLoS One.
2013;8(12):e83244. PMCID: PMC3862727
37.
Bararia D, Hildebrand JA, Stolz S, Haebe S,
Alig S, Trevisani CP, Osorio-Barrios F, Bartoschek MD, Mentz M, Pastore
A, Gaitzsch E, Heide M, Jurinovic V, Rautter K, Gunawardana J, Sabdia
MB, Szczepanowski M, Richter J, Klapper W, Louissaint A, Ludwig C,
Bultmann S, Leonhardt H, Eustermann S, Hopfner KP, Hiddemann W, von
Bergwelt-Baildon M, Steidl C, Kridel R, Tobin JWD, Gandhi MK, Weinstock
DM, Schmidt-Supprian M, Sárosi MB, Rudelius M, Passerini V, Mautner J,
Weigert O. Cathepsin S
Alterations Induce a Tumor-Promoting Immune
Microenvironment in Follicular Lymphoma. Cell
Rep. 2020 May 5;31(5):107522.
38.
Ramírez-Komo JA, Delaney MA, Straign D, Lukin
K, Tsang M, Iritani BM, Hagman J. Spontaneous loss of B
lineage transcription factors leads to pre-B leukemia in
Ebf1+/-Bcl-xLTg mice.
Oncogenesis. 2017 Jul 10;6(7):e355. PMCID: PMC5541707
39.
Bohle V, Döring C, Hansmann M-L, Küppers R. Role of early B-cell factor 1 (EBF1) in
Hodgkin lymphoma. Leukemia. 2013 Mar;27(3):671–679.
40.
Thomas N, Dreval K, Gerhard DS, Hilton LK,
Abramson JS, Ambinder RF, Barta S, Bartlett NL, Bethony J, Bhatia K,
Bowen J, Bryan AC, Cesarman E, Casper C, Chadburn A, Cruz M, Dittmer DP,
Dyer MA, Farinha P, Gastier-Foster JM, Gerrie AS, Grande BM, Greiner T,
Griner NB, Gross TG, Harris NL, Irvin JD, Jaffe ES, Henry D, Huppi R,
Leal FE, Lee MS, Martin JP, Martin MR, Mbulaiteye SM, Mitsuyasu R,
Morris V, Mullighan CG, Mungall AJ, Mungall K, Mutyaba I, Nokta M,
Namirembe C, Noy A, Ogwang MD, Omoding A, Orem J, Ott G, Petrello H,
Pittaluga S, Phelan JD, Ramos JC, Ratner L, Reynolds SJ, Rubinstein PG,
Sissolak G, Slack G, Soudi S, Swerdlow SH, Traverse-Glehen A, Wilson WH,
Wong J, Yarchoan R, ZenKlusen JC, Marra MA, Staudt LM, Scott DW, Morin
RD. Genetic subgroups inform on pathobiology in adult and pediatric
Burkitt lymphoma. Blood. 2023 Feb 23;141(8):904–916. PMCID:
PMC10023728
41.
Hübschmann D, Kleinheinz K, Wagener R, Bernhart
SH, López C, Toprak UH, Sungalee S, Ishaque N, Kretzmer H, Kreuz M,
Waszak SM, Paramasivam N, Ammerpohl O, Aukema SM, Beekman R, Bergmann
AK, Bieg M, Binder H, Borkhardt A, Borst C, Brors B, Bruns P, Carrillo
de Santa Pau E, Claviez A, Doose G, Haake A, Karsch D, Haas S, Hansmann
ML, Hoell JI, Hovestadt V, Huang B, Hummel M, Jäger-Schmidt C,
Kerssemakers JNA, Korbel JO, Kube D, Lawerenz C, Lenze D, Martens JHA,
Ott G, Radlwimmer B, Reisinger E, Richter J, Rico D, Rosenstiel P,
Rosenwald A, Schillhabel M, Stilgenbauer S, Stadler PF, Martín-Subero
JI, Szczepanowski M, Warsow G, Weniger MA, Zapatka M, Valencia A,
Stunnenberg HG, Lichter P, Möller P, Loeffler M, Eils R, Klapper W,
Hoffmann S, Trümper L, ICGC MMML-Seq consortium, ICGC DE-Mining
consortium, BLUEPRINT consortium, Küppers R, Schlesner M, Siebert R.
Mutational mechanisms shaping the coding and noncoding genome of
germinal center derived B-cell lymphomas.
Leukemia. 2021 Jul;35(7):2002–2016. PMCID: PMC8257491
42.
Chapuy B, Stewart C, Dunford AJ, Kim J,
Kamburov A, Redd RA, Lawrence MS, Roemer MGM, Li AJ, Ziepert M, Staiger
AM, Wala JA, Ducar MD, Leshchiner I, Rheinbay E, Taylor-Weiner A,
Coughlin CA, Hess JM, Pedamallu CS, Livitz D, Rosebrock D, Rosenberg M,
Tracy AA, Horn H, van Hummelen P, Feldman AL, Link BK, Novak AJ, Cerhan
JR, Habermann TM, Siebert R, Rosenwald A, Thorner AR, Meyerson ML, Golub
TR, Beroukhim R, Wulf GG, Ott G, Rodig SJ, Monti S, Neuberg DS, Loeffler
M, Pfreundschuh M, Trümper L, Getz G, Shipp MA. Molecular subtypes of
diffuse large B cell lymphoma are associated with distinct
pathogenic mechanisms and outcomes. Nat Med. 2018 May;24(5):679–690.
PMCID: PMC6613387
43.
Morin RD, Johnson NA, Severson TM, Mungall AJ,
An J, Goya R, Paul JE, Boyle M, Woolcock BW, Kuchenbauer F, Yap D,
Humphries RK, Griffith OL, Shah S, Zhu H, Kimbara M, Shashkin P, Charlot
JF, Tcherpakov M, Corbett R, Tam A, Varhol R, Smailus D, Moksa M, Zhao
Y, Delaney A, Qian H, Birol I, Schein J, Moore R, Holt R, Horsman DE,
Connors JM, Jones S, Aparicio S, Hirst M, Gascoyne RD, Marra MA. Somatic
mutations altering EZH2 (Tyr641) in follicular
and diffuse large B-cell lymphomas of
germinal-center origin. Nat Genet. 2010 Feb;42(2):181–185. PMCID: PMC2850970
44.
Sneeringer CJ, Scott MP, Kuntz KW, Knutson SK,
Pollock RM, Richon VM, Copeland RA. Coordinated activities of wild-type
plus mutant EZH2 drive tumor-associated hypertrimethylation
of lysine 27 on histone H3 (H3K27) in human
B-cell lymphomas. Proc Natl Acad Sci U S A.
2010 Dec 7;107(49):20980–20985. PMCID: PMC3000297
45.
Mottok A, Hung SS, Chavez EA, Woolcock B,
Telenius A, Chong LC, Meissner B, Nakamura H, Rushton C, Viganò E,
Sarkozy C, Gascoyne RD, Connors JM, Ben-Neriah S, Mungall A, Marra MA,
Siebert R, Scott DW, Savage KJ, Steidl C. Integrative genomic
analysis identifies key pathogenic mechanisms in primary mediastinal
large B-cell lymphoma. Blood. 2019 Sep
5;134(10):802–813.
46.
Wang L, Yang JK, Kabaleeswaran V, Rice AJ, Cruz
AC, Park AY, Yin Q, Damko E, Jang SB, Raunser S, Robinson CV, Siegel RM,
Walz T, Wu H. The Fas-FADD death domain complex structure
reveals the basis of DISC assembly and disease mutations.
Nat Struct Mol Biol. 2010 Nov;17(11):1324–1329. PMCID: PMC2988912
47.
Scholl V, Stefanoff CG, Hassan R, Spector N,
Renault IZ. Mutations within the 5’
region of FAS/CD95 gene in nodal diffuse large
B-cell lymphoma. Leuk Lymphoma. 2007
May;48(5):957–963.
48.
Trinh DL, Scott DW, Morin RD, Mendez-Lago M, An
J, Jones SJM, Mungall AJ, Zhao Y, Schein J, Steidl C, Connors JM,
Gascoyne RD, Marra MA. Analysis of FOXO1 mutations in
diffuse large B-cell lymphoma. Blood.
2013;121(18):3666–3674. PMCID: PMC3643765
49.
Muppidi J, Schmitz R, Green JA, Green JA, Xiao
W, Larsen AB, Braun S, An J, Xu Y, Rosenwald A, Ott G, Gascoyne R,
Rimsza L, Campo E, Jaffe E, Delabie J, Smeland E, Braziel R, Tubbs R,
Cook J, Weisenburger D, Chan W, Vaidehi N, Staudt L, Cyster J. Loss of signaling via
Gα13 in germinal center B cell-derived
lymphoma. Nature. 2014;516:254–258.
50.
Qiu
Z, Khalife J, Ethiraj P, Jaafar C, Lin AP, Holder KN, Ritter JP, Chiou
L, Huelgas-Morales G, Aslam S, Zhang Z, Liu Z, Arya S, Gupta YK, Dahia
PLM, Aguiar RCT. IRF8-mutant B cell lymphoma
evades immunity through a CD74-dependent
deregulation of antigen processing and presentation in
MHCII complexes. Sci Adv. 2024 Jul 12;10(28):eadk2091.
PMCID: PMC11244530
51.
Choi J, Lee K, Ingvarsdottir K, Bonasio R,
Saraf A, Florens L, Washburn MP, Tadros S, Green MR, Busino L. Loss of
KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing
the mRNA decay factor Roquin2. Nat Cell
Biol. 2018 May;20(5):586–596. PMCID: PMC5926793
52.
Ganapathi KA, Jobanputra V, Iwamoto F, Jain P,
Chen J, Cascione L, Nahum O, Levy B, Xie Y, Khattar P, Hoehn D, Bertoni
F, Murty VV, Pittaluga S, Jaffe ES, Alobeid B, Mansukhani MM, Bhagat G.
The genetic landscape
of dural marginal zone lymphomas. Oncotarget. Impact Journals; 2016
May 27;7(28):43052–43061.
53.
Zhang J, Dominguez-Sola D, Hussein S, Lee JE,
Holmes AB, Bansal M, Vlasevska S, Mo T, Tang H, Basso K, Ge K,
Dalla-Favera R, Pasqualucci L. Disruption of KMT2D perturbs
germinal center B cell development and promotes
lymphomagenesis. Nat Med. 2015 Oct;21(10):1190–1198. PMCID: PMC5145002
54.
Beà
S, Valdés-Mas R, Navarro A, Salaverria I, Martín-Garcia D, Jares P, Giné
E, Pinyol M, Royo C, Nadeu F, Conde L, Juan M, Clot G, Vizán P, Croce
LD, Puente DA, López-Guerra M, Moros A, Roue G, Aymerich M, Villamor N,
Colomo L, Martínez A, Valera A, Martín-Subero JI, Amador V, Hernández L,
Rozman M, Enjuanes A, Forcada P, Muntañola A, Hartmann EM, Calasanz MJ,
Rosenwald A, Ott G, Hernández-Rivas JM, Klapper W, Siebert R, Wiestner
A, Wilson WH, Colomer D, López-Guillermo A, López-Otín C, Puente XS,
Campo E. Landscape of
somatic mutations and clonal evolution in mantle cell lymphoma.
PNAS. 2013;110(45):18250–18255.
55.
Louissaint A, Schafernak KT, Geyer JT, Kovach
AE, Ghandi M, Gratzinger D, Roth CG, Paxton CN, Kim S, Namgyal C, Morin
R, Morgan EA, Neuberg DS, South ST, Harris MH, Hasserjian RP, Hochberg
EP, Garraway LA, Harris NL, Weinstock DM. Pediatric-type nodal
follicular lymphoma: A biologically distinct lymphoma with frequent
MAPK pathway mutations. Blood. 2016 Aug
25;128(8):1093–1100. PMCID: PMC5000844
56.
Shin SY, Lee ST, Kim HJ, Ki CS, Jung CW, Kim
JW, Kim SH. BRAF V600E and MAP2K1 mutations in
hairy cell leukemia and splenic marginal zone lymphoma cases. Ann Lab
Med. 2015 Mar;35(2):257–259. PMCID: PMC4330180
57.
Pon
JR, Wong J, Saberi S, Alder O, Moksa M, Grace Cheng S-W, Morin GB,
Hoodless PA, Hirst M, Marra MA. MEF2B mutations in
non-Hodgkin lymphoma dysregulate cell migration by
decreasing MEF2B target gene activation. Nature
Communications [Internet]. 2015 Aug 6 [cited 2019 Dec 21];6(1):1–15.
Available from: https://www.nature.com/articles/ncomms8953
58.
Freie B, Carroll PA, Varnum-Finney BJ, Ramsey
EL, Ramani V, Bernstein I, Eisenman RN. A germline point mutation in the
MYC-FBW7 phosphodegron initiates hematopoietic
malignancies. Genes Dev. 2024 Apr 17;38(5-6):253–272. PMCID: PMC11065175
59.
Johnston JM, Carroll WL. C-myc hypermutation in
Burkitt’s lymphoma. Leuk Lymphoma. 1992
Dec;8(6):431–439.
60.
Pasqualucci L, Neumeister P, Goossens T,
Nanjangud G, Chaganti RS, Küppers R, Dalla-Favera R. Hypermutation of multiple
proto-oncogenes in B-cell diffuse large-cell
lymphomas. Nature. 2001 Jul 19;412(6844):341–346.
61.
Kuo
HP, Ezell SA, Hsieh S, Schweighofer KJ, Cheung LW, Wu S, Apatira M,
Sirisawad M, Eckert K, Liang Y, Hsu J, Chen CT, Beaupre D, Chang BY. The
role of PIM1 in the ibrutinib-resistant ABC
subtype of diffuse large B-cell lymphoma. Am
J Cancer Res. 2016;6(11):2489–2501. PMCID: PMC5126268
62.
González-Rincón J, Méndez M, Gómez S, García
JF, Martín P, Bellas C, Pedrosa L, Rodríguez-Pinilla SM, Camacho FI,
Quero C, Pérez-Callejo D, Rueda A, Llanos M, Gómez-Codina J, Piris MA,
Montes-Moreno S, Bárcena C, Rodríguez-Abreu D, Menárguez J, de la
Cruz-Merino L, Monsalvo S, Parejo C, Royuela A, Kwee I, Cascione L,
Arribas A, Bertoni F, Mollejo M, Provencio M, Sánchez-Beato M.
Unraveling transformation of follicular lymphoma to diffuse large B-cell lymphoma. PLoS One. 2019;14(2):e0212813.
PMCID: PMC6388933
63.
Hodson DJ, Shaffer AL, Xiao W, Wright GW,
Schmitz R, Phelan JD, Yang Y, Webster DE, Rui L, Kohlhammer H, Nakagawa
M, Waldmann TA, Staudt LM. Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2. Proc Natl
Acad Sci U S A. 2016 Apr 5;113(14):E2039–2046. PMCID: PMC4833274
64.
Gao
J, Sidiropoulou E, Walker I, Krupka JA, Mizielinski K, Usheva Z,
Samarajiwa SA, Hodson DJ. SGK1 mutations in
DLBCL generate hyperstable protein neoisoforms that promote
AKT independence. Blood. 2021 Sep 16;138(11):959–964.
PMCID: PMC8701626
65.
Fernando TM, Piskol R, Bainer R, Sokol ES,
Trabucco SE, Zhang Q, Trinh H, Maund S, Kschonsak M, Chaudhuri S,
Modrusan Z, Januario T, Yauch RL. Functional characterization of
SMARCA4 variants identified by targeted exome-sequencing of
131,668 cancer patients. Nat Commun. 2020 Nov 3;11(1):5551. PMCID: PMC7609548
66.
Nadeu F, Martín-García D, Clot G, Díaz-Navarro
A, Duran-Ferrer M, Navarro A, Vilarrasa-Blasi R, Kulis M, Royo R,
Gutiérrez-Abril J, Valdés-Mas R, López C, Chapaprieta V, Puiggrós M,
Castellano G, Costa D, Aymerich M, Jares P, Espinet B, Muntañola A,
Ribera‐Cortada I, Siebert R, Colomer D, Torrents D, Giné E,
López-Guillermo A, Küppers R, Martín-Subero J, Puente X, Beà S, Campo E.
Genomic and
epigenomic insights into the origin, pathogenesis and clinical behavior
of mantle cell lymphoma subtypes. Blood. 2020;
67.
Reddy A, Zhang J, Davis NS, Moffitt AB, Love
CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg
ML, Nørgaard P, Pedersen M, Gang AO, Høgdall E, Heavican TB, Lone W,
Iqbal J, Qin Q, Li G, Kim SY, Healy J, Richards KL, Fedoriw Y,
Bernal-Mizrachi L, Koff JL, Staton AD, Flowers CR, Paltiel O,
Goldschmidt N, Calaminici M, Clear A, Gribben J, Nguyen E, Czader MB,
Ondrejka SL, Collie A, Hsi ED, Tse E, Au-Yeung RKH, Kwong YL, Srivastava
G, Choi WWL, Evens AM, Pilichowska M, Sengar M, Reddy N, Li S, Chadburn
A, Gordon LI, Jaffe ES, Levy S, Rempel R, Tzeng T, Happ LE, Dave T,
Rajagopalan D, Datta J, Dunson DB, Dave SS. Genetic and Functional
Drivers of Diffuse Large B Cell Lymphoma. Cell. 2017
Oct;171(2):481–494.e15. PMCID: PMC5659841
68.
Melzner I, Bucur AJ, Brüderlein S, Dorsch K,
Hasel C, Barth TFE, Leithäuser F, Möller P. Biallelic mutation of
SOCS-1 impairs JAK2 degradation and sustains
phospho-JAK2 action in the MedB-1 mediastinal
lymphoma line. Blood. 2005 Mar 15;105(6):2535–2542.
69.
Weniger MA, Melzner I, Menz CK, Wegener S,
Bucur AJ, Dorsch K, Mattfeldt T, Barth TFE, Möller P. Mutations of the tumor
suppressor gene SOCS-1 in classical Hodgkin
lymphoma are frequent and associated with nuclear
phospho-STAT5 accumulation. Oncogene. 2006 Apr
27;25(18):2679–2684.
70.
Yildiz M, Li H, Bernard D, Amin NA, Ouillette
P, Jones S, Saiya-Cork K, Parkin B, Jacobi K, Shedden K, Wang S, Chang
AE, Kaminski MS, Malek SN. Activating STAT6 mutations in
follicular lymphoma. Blood. 2015 Jan 22;125(4):668–679. PMCID: PMC4729538
71.
Mentz M, Keay W, Strobl CD, Antoniolli M,
Adolph L, Heide M, Lechner A, Haebe S, Osterode E, Kridel R, Ziegenhain
C, Wange LE, Hildebrand JA, Shree T, Silkenstedt E, Staiger AM, Ott G,
Horn H, Szczepanowski M, Richter J, Levy R, Rosenwald A, Enard W,
Zimber-Strobl U, von Bergwelt-Baildon M, Hiddemann W, Klapper W,
Schmidt-Supprian M, Rudelius M, Bararia D, Passerini V, Weigert O.
PARP14 is a novel target in STAT6 mutant
follicular lymphoma. Leukemia. 2022 Sep;36(9):2281–2292. PMCID: PMC9417990
72.
Ritz O, Guiter C, Castellano F, Dorsch K,
Melzner J, Jais JP, Dubois G, Gaulard P, Möller P, Leroy K. Recurrent
mutations of the STAT6 DNA binding domain in primary
mediastinal B-cell lymphoma. Blood. 2009 Aug
6;114(6):1236–1242. PMCID: PMC2824656
73.
Venturutti L, Teater M, Zhai A, Chadburn A,
Babiker L, Kim D, Béguelin W, Lee TC, Kim Y, Chin CR, Yewdell WT, Raught
B, Phillip JM, Jiang Y, Staudt LM, Green MR, Chaudhuri J, Elemento O,
Farinha P, Weng AP, Nissen MD, Steidl C, Morin RD, Scott DW, Privé GG,
Melnick AM. TBL1XR1 Mutations Drive Extranodal Lymphoma by
Inducing a Pro-tumorigenic Memory
Fate. Cell. 2020 Jul 23;182(2):297–316.e27. PMCID: PMC7384961
74.
Compagno M, Lim WK, Grunn A, Nandula SV,
Brahmachary M, Shen Q, Bertoni F, Ponzoni M, Scandurra M, Califano A,
Bhagat G, Chadburn A, Dalla-Favera R, Pasqualucci L. Mutations of
multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma. Nature. 2009 Jun
4;459(7247):717–721. PMCID: PMC2973325
75.
Rossi D, Deaglio S, Dominguez-Sola D, Rasi S,
Vaisitti T, Agostinelli C, Spina V, Bruscaggin A, Monti S, Cerri M,
Cresta S, Fangazio M, Arcaini L, Lucioni M, Marasca R, Thieblemont C,
Capello D, Facchetti F, Kwee I, Pileri SA, Foà R, Bertoni F,
Dalla-Favera R, Pasqualucci L, Gaidano G. Alteration of
BIRC3 and multiple other NF-κB
pathway genes in splenic marginal zone lymphoma. Blood. 2011 Nov
3;118(18):4930–4934.
76.
Schmitz R, Hansmann ML, Bohle V, Martin-Subero
JI, Hartmann S, Mechtersheimer G, Klapper W, Vater I, Giefing M, Gesk S,
Stanelle J, Siebert R, Küppers R. TNFAIP3
(A20) is a tumor suppressor gene in Hodgkin
lymphoma and primary mediastinal B cell lymphoma. J Exp
Med. 2009 May 11;206(5):981–989. PMCID: PMC2715030
77.
Cheung KJJ, Johnson NA, Affleck JG, Severson T,
Steidl C, Ben-Neriah S, Schein J, Morin RD, Moore R, Shah SP, Qian H,
Paul JE, Telenius A, Relander T, Lam W, Savage K, Connors JM, Brown C,
Marra MA, Gascoyne RD, Horsman DE. Acquired
TNFRSF14 mutations in follicular lymphoma are associated
with worse prognosis. Cancer Res. 2010 Nov 15;70(22):9166–9174.
78.
Kato S, Han SY, Liu W, Otsuka K, Shibata H,
Kanamaru R, Ishioka C. Understanding the function-structure and
function-mutation relationships of P53 tumor suppressor protein by
high-resolution missense mutation analysis. Proc Natl Acad Sci U S A.
2003 Jul 8;100(14):8424–8429. PMCID: PMC166245
79.
Tiacci E, Ladewig E, Schiavoni G, Penson A,
Fortini E, Pettirossi V, Wang Y, Rosseto A, Venanzi A, Vlasevska S,
Pacini R, Piattoni S, Tabarrini A, Pucciarini A, Bigerna B, Santi A,
Gianni AM, Viviani S, Cabras A, Ascani S, Crescenzi B, Mecucci C,
Pasqualucci L, Rabadan R, Falini B. Pervasive mutations of
JAK-STAT pathway genes in classical Hodgkin
lymphoma. Blood. 2018 May 31;131(22):2454–2465. PMCID: PMC6634958
80.
Wilda M, Bruch J, Harder L, Rawer D, Reiter A,
Borkhardt A, Woessmann W. Inactivation of the ARF-MDM-2-p53 pathway in sporadic
Burkitt’s lymphoma in children. Leukemia. 2004
Mar;18(3):584–588.
81.
Fan
Z, Pei R, Sha K, Chen L, Wang T, Lu Y. Comprehensive characterization of
driver genes in diffuse large B cell lymphoma. Oncol Lett.
2020 Jul;20(1):382–390. PMCID: PMC7285964
82.
Almasmoum HA, Airhihen B, Seedhouse C, Winkler
GS. Frequent
loss of BTG1 activity and impaired interactions with the
Caf1 subunit of the Ccr4-Not deadenylase in
non-Hodgkin lymphoma. Leuk Lymphoma. 2021
Feb;62(2):281–290.
83.
Nie
M, Ren W, Ye X, Berglund M, Wang X, Fjordén K, Du L, Giannoula Y, Lei D,
Su W, Li W, Liu D, Linderoth J, Jiang C, Bao H, Jiang W, Huang H, Hou Y,
Zhu S, Enblad G, Jerkeman M, Wu K, Zhang H, Amini RM, Li ZM,
Pan-Hammarström Q. The dual role of CD70 in B-cell lymphomagenesis. Clin Transl Med. 2022
Dec;12(12):e1118. PMCID: PMC9722974
84.
Davis RE, Ngo VN, Lenz G, Tolar P, Young RM,
Romesser PB, Kohlhammer H, Lamy L, Zhao H, Yang Y, Xu W, Shaffer AL,
Wright G, Xiao W, Powell J, Jiang JK, Thomas CJ, Rosenwald A, Ott G,
Müller-Hermelink HK, Gascoyne RD, Connors JM, Johnson NA, Rimsza LM,
Campo E, Jaffe ES, Wilson WH, Delabie J, Smeland EB, Fisher RI, Braziel
RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Pierce SK, Staudt LM.
Chronic active B-cell-receptor signalling in
diffuse large B-cell lymphoma. Nature. 2010
Jan;463(7277):88–92. PMCID: PMC2845535
85.
Zmajkovicova K, Pawar S, Maier-Munsa S,
Maierhofer B, Wiest I, Skerlj R, Taveras AG, Badarau A.
Genotype-phenotype correlations in WHIM syndrome: A
systematic characterization of CXCR4WHIM variants. Genes
Immun. 2022 Sep;23(6):196–204. PMCID: PMC9519442
86.
Khodabakhshi AH, Morin RD, Fejes AP, Mungall
AJ, Mungall KL, Bolger-Munro M, Johnson NA, Connors JM, Gascoyne RD,
Marra MA, Birol I, Jones SJM. Recurrent targets of aberrant somatic
hypermutation in lymphoma. Oncotarget. 2012;3(11):1308–1319. PMCID: PMC3717795
87.
Gong C, Krupka JA, Gao J, Grigoropoulos NF,
Giotopoulos G, Asby R, Screen M, Usheva Z, Cucco F, Barrans S, Painter
D, Zaini NBM, Haupl B, Bornelöv S, Ruiz De Los Mozos I, Meng W, Zhou P,
Blain AE, Forde S, Matthews J, Khim Tan MG, Burke GAA, Sze SK, Beer P,
Burton C, Campbell P, Rand V, Turner SD, Ule J, Roman E, Tooze R,
Oellerich T, Huntly BJ, Turner M, Du MQ, Samarajiwa SA, Hodson DJ. Sequential inverse
dysregulation of the RNA helicases DDX3X and
DDX3Y facilitates MYC-driven
lymphomagenesis. Molecular Cell. 2021;
88.
Gomez F, Fisk B, McMichael JF, Mosior M, Foltz
JA, Skidmore ZL, Duncavage EJ, Miller CA, Abel H, Li YS, Russler-Germain
DA, Krysiak K, Watkins MP, Ramirez CA, Schmidt A, Martins Rodrigues F,
Trani L, Khanna A, Wagner JA, Fulton RS, Fronick CC, O’Laughlin MD,
Schappe T, Cashen AF, Mehta-Shah N, Kahl BS, Walker J, Bartlett NL,
Griffith M, Fehniger TA, Griffith OL. Ultra-Deep Sequencing
Reveals the Mutational Landscape of Classical
Hodgkin Lymphoma. Cancer Res Commun. 2023 Nov 15;3(11):2312–2330.
PMCID: PMC10648575
89.
Fangazio M, Ladewig E, Gomez K, Garcia-Ibanez
L, Kumar R, Teruya-Feldstein J, Rossi D, Filip I, Pan-Hammarström Q,
Inghirami G, Boldorini R, Ott G, Staiger AM, Chapuy B, Gaidano G, Bhagat
G, Basso K, Rabadan R, Pasqualucci L, Dalla-Favera R. Genetic mechanisms
of HLA-I loss and immune escape in diffuse large
B cell lymphoma. Proc Natl Acad Sci U S A. 2021 Jun
1;118(22):e2104504118. PMCID: PMC8179151
90.
Schmitz R, Wright GW, Huang DW, Johnson CA,
Phelan JD, Wang JQ, Roulland S, Kasbekar M, Young RM, Shaffer AL, Hodson
DJ, Xiao W, Yu X, Yang Y, Zhao H, Xu W, Liu X, Zhou B, Du W, Chan WC,
Jaffe ES, Gascoyne RD, Connors JM, Campo E, Lopez-Guillermo A, Rosenwald
A, Ott G, Delabie J, Rimsza LM, Tay Kuang Wei K, Zelenetz AD, Leonard
JP, Bartlett NL, Tran B, Shetty J, Zhao Y, Soppet DR, Pittaluga S,
Wilson WH, Staudt LM. Genetics and Pathogenesis of
Diffuse Large B-Cell Lymphoma. N Engl J Med. 2018 Apr
12;378(15):1396–1407. PMCID: PMC6010183
91.
Pasqualucci L, Trifonov V, Fabbri G, Ma J,
Rossi D, Chiarenza A, Wells VA, Grunn A, Messina M, Elliot O, Chan J,
Bhagat G, Chadburn A, Gaidano G, Mullighan CG, Rabadan R, Dalla-Favera
R. Analysis of the coding genome of diffuse large B-cell lymphoma. Nat Genet. 2011 Jul
31;43(9):830–837. PMCID: PMC3297422
92.
Ngo
VN, Young RM, Schmitz R, Jhavar S, Xiao W, Lim KH, Kohlhammer H, Xu W,
Yang Y, Zhao H, Shaffer AL, Romesser P, Wright G, Powell J, Rosenwald A,
Muller-Hermelink HK, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E,
Jaffe ES, Delabie J, Smeland EB, Fisher RI, Braziel RM, Tubbs RR, Cook
JR, Weisenburger DD, Chan WC, Staudt LM. Oncogenically active
MYD88 mutations in human lymphoma. Nature. 2011 Feb
3;470(7332):115–119. PMCID: PMC5024568
93.
Jungnickel B, Staratschek-Jox A, Bräuninger A,
Spieker T, Wolf J, Diehl V, Hansmann ML, Rajewsky K, Küppers R. Clonal
deleterious mutations in the IkappaBalpha gene in the
malignant cells in Hodgkin’s lymphoma. J Exp Med. 2000 Jan
17;191(2):395–402. PMCID: PMC2195754
94.
Thomas RK, Wickenhauser C, Tawadros S, Diehl V,
Küppers R, Wolf J, Schmitz R. Mutational
analysis of the IkappaBalpha gene in activated
B cell-like diffuse large B-cell lymphoma. Br J Haematol. 2004
Jul;126(1):50–54.
95.
Ennishi D, Healy S, Bashashati A, Saberi S,
Hother C, Mottok A, Chan FC, Chong L, Abraham L, Kridel R, Boyle M,
Meissner B, Aoki T, Takata K, Woolcock BW, Viganò E, Gold M, Molday LL,
Molday RS, Telenius A, Li MY, Wretham N, Dos Santos N, Wong M, Viller
NN, Uger RA, Duns G, Baticados A, Madero A, Bristow BN, Farinha P, Slack
GW, Ben-Neriah S, Lai D, Zhang AW, Salehi S, Shulha HP, Chiu DS,
Mostafavi S, Gerrie AS, Huang DW, Rushton C, Villa D, Sehn LH, Savage
KJ, Mungall AJ, Weng AP, Bally MB, Morin RD, Cohen Freue GV, Staudt LM,
Connors JM, Marra MA, Shah SP, Gascoyne RD, Scott DW, Steidl C.
TMEM30A loss-of-function mutations drive lymphomagenesis
and confer therapeutically exploitable vulnerability in B-cell lymphoma. Nat Med. 2020 Apr;26(4):577–588.
PMCID: PMC8480332
96.
Skalniak L, Mizgalska D, Zarebski A,
Wyrzykowska P, Koj A, Jura J. Regulatory
feedback loop between NF-kappaB and MCP-1-induced protein 1 RNase.
FEBS J. 2009 Oct;276(20):5892–5905.