Table of Contents
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
3 | Mutations are unlikely to be relevant to BL |
Warnings
The variants reported in BL in this gene failed QC
See below or the study page for more information ## Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| BL | GAMBL genomes+capture | 0.23 |
| BL | Thomas cohort | 0.00 |
| BL | Panea cohort | 1.00 |
Mutation pattern and selective pressure estimates
| Entity | Missense dN/dS | Nonsense dN/dS | Q value |
|---|---|---|---|
| BL | 0.0000 | 0 | 1.0000 |
| FL | 1.4739 | 0 | 1.0000 |
| DLBCL | 0.0000 | 0 | 0.9986 |
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Expression
Representative Mutations
BL1
Rating ★ ☆ ☆ ☆ ☆
Rating ★ ☆ ☆ ☆ ☆
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References
1.
Panea R, Love C, Shingleton JR, Reddy A, Bailey
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Chao N, Agajanian M, Major M, Fedoriw Y, Richards K, Rymkiewicz G, Miles
R, Alobeid B, Bhagat G, Flowers C, Ondrejka S, Hsi E, Choi W, Au-Yeung
R, Hartmann W, Lenz G, Meyerson H, Lin YY, Zhuang Y, Luftig M, Waldrop
A, Dave T, Thakkar D, Sahay H, Li G, Palus B, Seshadri V, Kim S,
Gascoyne R, Levy S, Mukhopadhyay M, Dunson D, Dave S. The whole genome
landscape of Burkitt lymphoma subtypes. Blood. 2019;