Table of Contents
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | Role of GBP7 mutations in FL requires confirmation |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| FL | GAMBL genomes | 0.23 |
Mutation pattern and selective pressure estimates
| Entity | Missense dN/dS | Nonsense dN/dS | Q value |
|---|---|---|---|
| BL | 0.5551 | 0 | 1.0000 |
| FL | 0.8417 | 0 | 1.0000 |
| DLBCL | 0.0000 | 0 | 0.9986 |
Visualizations
Protein
View coding variants in ProteinPaint hg19 or hg38
Genome
View all variants in GenomePaint hg19 or hg38
Expression
History
%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
title Publication timing
2023-07-26 : Russler-Germain : FL
References
1.
Russler-Germain DA, Krysiak K, Ramirez CA,
Mosior M, Watkins MP, Gomez F, Skidmore ZL, Trani L, Gao F, Geyer S,
Cashen A, Mehta-Shah N, Kahl B, Bartlett N, Alderuccio J, Lossos I,
Ondrejka S, Hsi E, Martin P, Leonard J, Griffith M, Griffith O, Fehniger
T. Mutations
associated with progression in follicular lymphoma predict inferior
outcomes at diagnosis: Alliance A151303. Blood
Advances. 2023;7:5524–5539.