Overview
Mutations in this gene are relatively rare in DLBCL overall.
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
| 2 | Role of HLA-DMA mutations in DLBCL requires confirmation |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 0.38 |
| DLBCL | Schmitz cohort | 1.28 |
| DLBCL | Reddy cohort | NA |
| DLBCL | Chapuy cohort | 1.71 |
Mutation pattern and selective pressure estimates
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