Relevance tier by entity

Entity Tier Description
BL 3 Mutations are unlikely to be relevant to BL

Warnings

The variants reported in this gene failed QC

Mutation incidence in large patient cohorts (GAMBL reanalysis)

BL

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Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 2.813 0
DLBCL No No 0.000 0
FL No No 0.000 0

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Representative Mutations

Rating ★ ☆ ☆ ☆ ☆

All Mutations

1092 516

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References

1.
Love C, Sun Z, Jima D, Li G, Zhang J, Miles R, Richards KL, Dunphy CH, Choi WWL, Srivastava G, Lugar PL, Rizzieri DA, Lagoo AS, Bernal-Mizrachi L, Mann KP, Flowers CR, Naresh KN, Evens AM, Chadburn A, Gordon LI, Czader MB, Gill JI, Hsi ED, Greenough A, Moffitt AB, McKinney M, Banerjee A, Grubor V, Levy S, Dunson DB, Dave SS. The genetic landscape of mutations in Burkitt lymphoma. Nat Genet. 2012 Dec;44(12):1321–1325. PMCID: PMC3674561