[IGLL5]
Mutation tier
| Entity | Tier |
|---|---|
| BL | 2 |
| DLBCL | 2 |
| FL | 2 |
Mutation incidence
| Entity | study | frequency (%) |
|---|---|---|
| BL | GAMBL genomes+capture | 26.33 |
| BL | Thomas cohort | 25.00 |
| BL | Panea cohort | 23.80 |
| DLBCL | GAMBL genomes | 41.10 |
| DLBCL | Schmitz cohort | 36.00 |
| DLBCL | Reddy cohort | 16.10 |
| DLBCL | Chapuy cohort | 9.00 |
| FL | GAMBL genomes | 35.33 |
Mutation pattern
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | Yes | Yes | 7.850 | 3.210 |
| DLBCL | Yes | Yes | 3.376 | 5.315 |
| FL | Yes | Yes | 4.830 | 9.846 |
aSHM regions
| chr_name | hg19_start | hg19_end | region | regulatory_comment |
|---|---|---|---|---|
| chr22 | 23229554 | 23232042 | TSS | NA |
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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