Table of Contents

Relevance tier by entity

Entity Tier Description
BL 1 High-confidence BL gene
DLBCL 1 High-confidence DLBCL gene
FL 1 High-confidence FL gene
PMBL 2 Role of IGLL5 mutations in PMBL requires confirmation

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity Collection N mutated Incidence 95% CI
DLBCL GAMBL without Reddy 1,089 327 0.3003 [0.2731,0.3275]
DLBCL GAMBL with Reddy 2,088 488 0.2337 [0.2156,0.2519]
DLBCL BC 231 85 0.3680 [0.3058,0.4302]
DLBCL Dana-Farber 303 28 0.0924 [0.0598,0.125]
DLBCL NCI 470 169 0.3596 [0.3162,0.403]
DLBCL Reddy 999 161 0.1612 [0.1384,0.184]
DLBCL DLBCL_ICGC 85 45 0.5294 [0.4233,0.6355]

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Mutation pattern and selective pressure estimates

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aSHM regions

chr_name hg19_start hg19_end region regulatory_comment
chr22 23229554 23232042 TSS NA

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Expression

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References

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