Overview
The IL16 gene, which encodes a pro-inflammatory cytokine, plays a role in immune responses. IL-16 is highly expressed in the activated B-cell-like (ABC) subtype of DLBCL compared to the germinal center B-cell-like (GCB) subtype. The role of mutations in lymphomagenesis is not understood. Overall, the mutation rate of IL16 is relatively low in DLBCL.
Relevance tier by entity
Failed to render page: conflicting chdir during another chdir block
Mutation incidence in large patient cohorts (GAMBL reanalysis)
DLBCL
Failed to render page: conflicting chdir during another chdir block
BL
Failed to render page: conflicting chdir during another chdir block
FL
Failed to render page: conflicting chdir during another chdir block
Mutation pattern and selective pressure estimates
Failed to render page: conflicting chdir during another chdir block
Failed to render page: conflicting chdir during another chdir block
Expression
