Table of Contents

Relevance tier by entity

Entity Tier Description
BL 2 Role of KLHL26 mutations in BL requires confirmation

Mutation incidence in large patient cohorts (GAMBL reanalysis)

FL

pathology Collection N mutated Incidence CI
FL GAMBL without Crouch 642 3 0.0047 [-6e-04,0.0099]
FL GAMBL with Crouch 1,189 3 0.0025 [-3e-04,0.0054]
FL BC 379 0 0.0003 [0,0.0019]
FL Kalmbach 164 3 0.0183 [0,0.0388]
FL Crouch 547 0 0.0002 [0,0.0013]
FL FL_ICGC 99 0 0.0010 [0,0.0073]

BL

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DLBCL

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Mutation pattern and selective pressure estimates

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Expression

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References

1.
Burkhardt B, Michgehl U, Rohde J, Erdmann T, Berning P, Reutter K, Rohde M, Borkhardt A, Burmeister T, Dave S, Tzankov A, Dugas M, Sandmann S, Fend F, Finger J, Mueller S, Gökbuget N, Haferlach T, Kern W, Hartmann W, Klapper W, Oschlies I, Richter J, Kontny U, Lutz M, Maecker-Kolhoff B, Ott G, Rosenwald A, Siebert R, von Stackelberg A, Strahm B, Woessmann W, Zimmermann M, Zapukhlyak M, Grau M, Lenz G. Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age. Nat Commun. 2022 Jul 6;13(1):3881. PMCID: PMC9259584

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