[LAPTM5]
Mutation tier
| Entity | Tier | Description |
|---|---|---|
| FL | 2 | relevance in FL not firmly established |
Mutation incidence
| Entity | source | frequency (%) |
|---|---|---|
| FL | GAMBL genomes | 5.77 |
Mutation pattern
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | Yes | No | 0.000 | 34.096 |
| DLBCL | Yes | No | 4.311 | 46.640 |
| FL | Yes | Yes | 15.566 | 93.829 |
aSHM regions
| chr_name | hg19_start | hg19_end | region | regulatory_comment |
|---|---|---|---|---|
| chr1 | 31229012 | 31232011 | TSS | NA |
[!NOTE] First described in FL in 2021 by Hübschmann D
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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