MAP3K14
History
%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
title Publication timing
2011-11-03 : Rossi : MZL
2012-06-01 : Otto : PMBL
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
| 1 | high-confidence MZL gene1 | |
| 1 | high-confidence PMBL/cHL/GZL gene2 |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL Exome | 0.162 |
References
1.
Rossi D, Deaglio S, Dominguez-Sola D, Rasi S,
Vaisitti T, Agostinelli C, Spina V, Bruscaggin A, Monti S, Cerri M,
Cresta S, Fangazio M, Arcaini L, Lucioni M, Marasca R, Thieblemont C,
Capello D, Facchetti F, Kwee I, Pileri SA, Foà R, Bertoni F,
Dalla-Favera R, Pasqualucci L, Gaidano G. Alteration of
BIRC3 and multiple other NF-κB
pathway genes in splenic marginal zone lymphoma. Blood. 2011 Nov
3;118(18):4930–4934.
2.
Otto
C, Giefing M, Massow A, Vater I, Gesk S, Schlesner M, Richter J, Klapper
W, Hansmann ML, Siebert R, Küppers R. Genetic lesions
of the TRAF3 and MAP3K14 genes in classical
Hodgkin lymphoma. Br J Haematol. 2012
Jun;157(6):702–708.