Table of Contents
Overview
Mutations in MPEG1 have been described in DLBCL1 with the overall rate of mutations somewhat variable across studies. MPEG1 is one of a number of genes affected by aberrant somatic hypermutation in B-cell lymphomas, which complicates the interpretation of mutations at this locus. Coding and non-coding MPEG1 mutations are a feature of the MCD genetic subgroup of DLBCL.
Relevance tier by entity
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Mutation incidence in large patient cohorts (GAMBL reanalysis)
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Mutation pattern and selective pressure estimates
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Expression
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