Table of Contents
Relevance tier by entity
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Warnings
The variants reported in this gene in DLBCL failed QC
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 2.10 |
| DLBCL | Schmitz cohort | 4.47 |
| DLBCL | Reddy cohort | 2.70 |
| DLBCL | Chapuy cohort | 2.14 |
Mutation pattern and selective pressure estimates
| Entity | Missense dN/dS | Nonsense dN/dS | Q value |
|---|---|---|---|
| BL | 0.5538 | 3.5217 | 1.0000 |
| FL | 0.5184 | 0.0000 | 1.0000 |
| DLBCL | 0.0000 | 0.0000 | 0.9986 |
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Expression
All Mutations
Reddy_2133T Reddy_2260T Reddy_2482T Reddy_2534T Reddy_2544T Reddy_2577T Reddy_2603T Reddy_2771T Reddy_2805T Reddy_2828T Reddy_2838T Reddy_2909T Reddy_2947T Reddy_2955T Reddy_2956T Reddy_3389T Reddy_3412T Reddy_3422T Reddy_3519T Reddy_3532T Reddy_3586T Reddy_3659T Reddy_3675T Reddy_3681T Reddy_3734T Reddy_3743T Reddy_3816T Reddy_3820T Reddy_3829T Reddy_3846T Reddy_3849T Reddy_3889T Reddy_3895T Reddy_3906T Reddy_3931T
History
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timeline
title Publication timing
2017-10-10 : Reddy : DLBCL
References
1.
Reddy A, Zhang J, Davis NS, Moffitt AB, Love
CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg
ML, Nørgaard P, Pedersen M, Gang AO, Høgdall E, Heavican TB, Lone W,
Iqbal J, Qin Q, Li G, Kim SY, Healy J, Richards KL, Fedoriw Y,
Bernal-Mizrachi L, Koff JL, Staton AD, Flowers CR, Paltiel O,
Goldschmidt N, Calaminici M, Clear A, Gribben J, Nguyen E, Czader MB,
Ondrejka SL, Collie A, Hsi ED, Tse E, Au-Yeung RKH, Kwong YL, Srivastava
G, Choi WWL, Evens AM, Pilichowska M, Sengar M, Reddy N, Li S, Chadburn
A, Gordon LI, Jaffe ES, Levy S, Rempel R, Tzeng T, Happ LE, Dave T,
Rajagopalan D, Datta J, Dunson DB, Dave SS. Genetic and Functional
Drivers of Diffuse Large B Cell Lymphoma. Cell. 2017
Oct;171(2):481–494.e15. PMCID: PMC5659841