Table of Contents

Relevance tier by entity

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Warnings

The variants reported in this gene in DLBCL failed QC

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 2.10
DLBCL Schmitz cohort 4.47
DLBCL Reddy cohort 2.70
DLBCL Chapuy cohort 2.14

Mutation pattern and selective pressure estimates

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Expression

All Mutations

Reddy_2133T Reddy_2260T Reddy_2482T Reddy_2534T Reddy_2544T Reddy_2577T Reddy_2603T Reddy_2771T Reddy_2805T Reddy_2828T Reddy_2838T Reddy_2909T Reddy_2947T Reddy_2955T Reddy_2956T Reddy_3389T Reddy_3412T Reddy_3422T Reddy_3519T Reddy_3532T Reddy_3586T Reddy_3659T Reddy_3675T Reddy_3681T Reddy_3734T Reddy_3743T Reddy_3816T Reddy_3820T Reddy_3829T Reddy_3846T Reddy_3849T Reddy_3889T Reddy_3895T Reddy_3906T Reddy_3931T

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References

1.
Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg ML, Nørgaard P, Pedersen M, Gang AO, Høgdall E, Heavican TB, Lone W, Iqbal J, Qin Q, Li G, Kim SY, Healy J, Richards KL, Fedoriw Y, Bernal-Mizrachi L, Koff JL, Staton AD, Flowers CR, Paltiel O, Goldschmidt N, Calaminici M, Clear A, Gribben J, Nguyen E, Czader MB, Ondrejka SL, Collie A, Hsi ED, Tse E, Au-Yeung RKH, Kwong YL, Srivastava G, Choi WWL, Evens AM, Pilichowska M, Sengar M, Reddy N, Li S, Chadburn A, Gordon LI, Jaffe ES, Levy S, Rempel R, Tzeng T, Happ LE, Dave T, Rajagopalan D, Datta J, Dunson DB, Dave SS. Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma. Cell. 2017 Oct;171(2):481–494.e15. PMCID: PMC5659841

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