Table of Contents

Overview

Mutations in this gene are relatively rare in DLBCL overall but show a pattern of inactivation.

Relevance tier by entity

Entity Tier Description
BL 2 Role of NCOR2 mutations in BL requires confirmation
MZL 1 High-confidence MZL gene
PMBL 2 Role of NCOR2 mutations in PMBL requires confirmation

Mutation incidence in large patient cohorts (GAMBL reanalysis)

BL

pathology Collection N mutated Incidence CI
BL GAMBL without Panea 309 0 0 [0,0]
BL GAMBL without ICGC/Zhou 320 0 0 [0,0]
BL GAMBL with Panea 410 0 0 [0,0]
BL BLGSP 219 0 0 [0,0]
BL Zhou/ICGC 90 0 0 [0,0]
BL Panea 101 0 0 [0,0]

Mutation pattern and selective pressure estimates

Entity Missense dN/dS Nonsense dN/dS Q value
BL 0.7017 0 1.0000
FL 0.4376 0 1.0000
DLBCL 0.0000 0 0.9986

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Expression

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References

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Citing

If you use the information or data from this site, please cite

Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.

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