[OSBPL10]
Mutation tier
| Entity | Tier |
|---|---|
| BL | 2 |
| DLBCL | 1 |
Mutation incidence
| Entity | study | frequency (%) |
|---|---|---|
| BL | GAMBL genomes+capture | 2.08 |
| BL | Thomas cohort | 2.10 |
| BL | Panea cohort | 3.00 |
| DLBCL | GAMBL genomes | 8.80 |
| DLBCL | Schmitz cohort | 14.30 |
| DLBCL | Reddy cohort | 2.30 |
| DLBCL | Chapuy cohort | 2.60 |
Mutation pattern
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | Yes | No | 4.102 | 11.721 |
| DLBCL | Yes | Yes | 12.983 | 0.000 |
| FL | Yes | Yes | 5.877 | 8.779 |
aSHM regions
| chr_name | hg19_start | hg19_end | region | regulatory_comment |
|---|---|---|---|---|
| chr3 | 32020518 | 32024930 | TSS-1 | active_promoter |
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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