Table of Contents
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in PMBL/cHL/GZL not firmly established |
 |
1 | high-confidence BL gene1 |
 |
1 | high-confidence DLBCL gene1 |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
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Cannot include /BL_PCBP1.md - does not exist yet
Mutation pattern and selective pressure estimates
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PCBP1 Hotspots
| Chromosome | Coordinate (hg19) | ref>alt | HGVSp |
|---|---|---|---|
| chr2 | 70315424 | C>G | Y183* |
| chr2 | 70315425 | C>T | Q184* |
| chr2 | 70315439 | ->AGCT | S190* |
| chr2 | 70315457 | C>A | C194* |
Cannot include /browser_PCBP1.md - does not exist yet
Expression
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References
1.
Schmitz R, Young RM, Ceribelli M, Jhavar S,
Xiao W, Zhang M, Wright G, Shaffer AL, Hodson DJ, Buras E, Liu X, Powell
J, Yang Y, Xu W, Zhao H, Kohlhammer H, Rosenwald A, Kluin P,
Müller-Hermelink HK, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E,
Jaffe ES, Delabie J, Smeland EB, Ogwang MD, Reynolds SJ, Fisher RI,
Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Pittaluga S,
Wilson W, Waldmann TA, Rowe M, Mbulaiteye SM, Rickinson AB, Staudt LM.
Burkitt lymphoma pathogenesis and therapeutic targets from structural
and functional genomics. Nature. 2012 Oct 4;490(7418):116–120. PMCID: PMC3609867