PCDHB11

Relevance tier by entity

Entity Tier Description
DLBCL 2 relevance in DLBCL not firmly established

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 1.53
DLBCL Schmitz cohort 2.98
DLBCL Reddy cohort 1.20
DLBCL Chapuy cohort 1.28

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 2.106 0.000
DLBCL No No 0.848 11.264
FL No No 1.816 0.000

[!NOTE] First described in DLBCL in 2013 by Morin RD

View coding variants in ProteinPaint hg19 or hg38

image

View all variants in GenomePaint hg19 or hg38

image ## PCDHB11 Expression image