PLXNB3
History
| Entity | Tier | Description |
|---|---|---|
| 2 | relevance in MZL not firmly established | |
| 2 | relevance in MCL not firmly established |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| MCL | GAMBL genomes | 0 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 2.316 | 0 |
| DLBCL | No | No | 1.330 | 0 |
| FL | No | No | 0.000 | 0 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
## PLXNB3
Expression
## References 1. Zhang J,
Jima D, Moffitt AB, Liu Q, Czader M, Hsi ED, Fedoriw Y, Dunphy CH,
Richards KL, Gill JI, Sun Z, Love C, Scotland P, Lock E, Levy S, Hsu DS,
Dunson D, Dave SS. The genomic landscape of mantle cell lymphoma is
related to the epigenetically determined chromatin state of normal B
cells. Blood. 2014 May 8;123(19):2988–2996. 2. Spina V, Khiabanian H,
Messina M, Monti S, Cascione L, Bruscaggin A, Spaccarotella E, Holmes
AB, Arcaini L, Lucioni M, Tabbò F, Zairis S, Diop F, Cerri M, Chiaretti
S, Marasca R, Ponzoni M, Deaglio S, Ramponi A, Tiacci E, Pasqualucci L,
Paulli M, Falini B, Inghirami G, Bertoni F, Foà R, Rabadan R, Gaidano G,
Rossi D. The genetics of nodal marginal zone lymphoma. Blood. 2016 Sep
8;128(10):1362–1373.


