Table of Contents

Relevance tier by entity

Entity Tier Description
MZL 1 high-confidence MZL gene1
PMBL 1 high-confidence PMBL/cHL/GZL gene
DLBCL 2 low-confidence DLBCL gene
FL 1 high-confidence FL gene

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 5.54
DLBCL Schmitz cohort 7.66
DLBCL Reddy cohort 5.21
DLBCL Chapuy cohort 5.56
FL GAMBL genomes 3.70

Mutation pattern and selective pressure estimates

Cannot include /dnds_PTPRD.md - does not exist yet

PTPRD Hotspots

Chromosome Coordinate (hg19) ref>alt HGVSp
chr9 8376670 T>G Q1481H

Cannot include /browser_PTPRD.md - does not exist yet

Expression

Cannot include /mermaid_PTPRD.md - does not exist yet

References

1.
Spina V, Khiabanian H, Messina M, Monti S, Cascione L, Bruscaggin A, Spaccarotella E, Holmes AB, Arcaini L, Lucioni M, Tabbò F, Zairis S, Diop F, Cerri M, Chiaretti S, Marasca R, Ponzoni M, Deaglio S, Ramponi A, Tiacci E, Pasqualucci L, Paulli M, Falini B, Inghirami G, Bertoni F, Foà R, Rabadan R, Gaidano G, Rossi D. The genetics of nodal marginal zone lymphoma. Blood. 2016 Sep 8;128(10):1362–1373. PMCID: PMC5016706

Citing

If you use the information or data from this site, please cite

Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.

Disclaimer

The content in these pages has been populated, in part, by an automated process. Although we have scrutinized every page to ensure accuracy, errors will inevitably exist. If you find an error please report it as an issue and we will address it.

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

You are free to:

Share — copy and redistribute the material in any medium or format for any purpose, even commercially.

Adapt — remix, transform, and build upon the material for any purpose, even commercially. The licensor cannot revoke these freedoms as long as you follow the license terms.