PTPRK

Relevance tier by entity

Entity Tier Description
DLBCL 2 relevance in DLBCL not firmly established

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 4.21
DLBCL Schmitz cohort 3.62
DLBCL Reddy cohort 3.30
DLBCL Chapuy cohort 6.41

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 2.146 0.000
DLBCL No No 1.555 1.797
FL No No 1.875 5.021

[!NOTE] First described in DLBCL in 2017 by Reddy A

View coding variants in ProteinPaint hg19 or hg38

image

View all variants in GenomePaint hg19 or hg38

image ## PTPRK Expression image