RFXAP
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | low-confidence DLBCL gene |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 1.34 |
| DLBCL | Schmitz cohort | 1.28 |
| DLBCL | Reddy cohort | 0.60 |
| DLBCL | Chapuy cohort | NA |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 2.222 | 91.553 |
| DLBCL | No | No | 3.462 | 29.787 |
| FL | No | No | 4.119 | 0.000 |
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Expression
References
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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