Relevance tier by entity

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Mutation incidence in large patient cohorts (GAMBL reanalysis)

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Mutation pattern and selective pressure estimates

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RHOA Hotspots

Chromosome Coordinate (hg19) ref>alt HGVSp
chr3 49413010 G>A R5W
chr3 49413009 C>T R5Q
chr3 49412923 A>C Y34D
chr3 49412922 T>A Y34F
chr3 49412899 A>G Y42H
chr3 49412898 T>G Y42S
chr3 49412898 T>C Y42C

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Expression

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References

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Zhang J, Grubor V, Love CL, Banerjee A, Richards KL, Mieczkowski PA, Dunphy C, Choi W, Au WY, Srivastava G, Lugar PL, Rizzieri DA, Lagoo AS, Bernal-Mizrachi L, Mann KP, Flowers C, Naresh K, Evens A, Gordon LI, Czader M, Gill JI, Hsi ED, Liu Q, Fan A, Walsh K, Jima D, Smith LL, Johnson AJ, Byrd JC, Luftig MA, Ni T, Zhu J, Chadburn A, Levy S, Dunson D, Dave SS. Genetic heterogeneity of diffuse large B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 2013;110:1398–1403. PMCID: PMC3557051