RHOH

Relevance tier by entity

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Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 1.15
DLBCL Schmitz cohort 0.43
DLBCL Reddy cohort 0.10
DLBCL Chapuy cohort NA

Mutation pattern and selective pressure estimates

Entity Missense dN/dS Nonsense dN/dS Q value
BL 0 41.5517 1.0000
FL 0 0.0000 1.0000
DLBCL 0 0.0000 0.9986

aSHM regions

chr_name hg19_start hg19_end region regulatory_comment
chr4 40193105 40204231 TSS active_promoter

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Expression

References

1.
Pasqualucci L, Neumeister P, Goossens T, Nanjangud G, Chaganti RS, Küppers R, Dalla-Favera R. Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas. Nature. 2001 Jul 19;412(6844):341–346.

Citing

If you use the information or data from this site, please cite

Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.

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