SEL1L3
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | Role of SEL1L3 mutations in DLBCL requires confirmation |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 5.16 |
| DLBCL | Schmitz cohort | 4.04 |
| DLBCL | Reddy cohort | 2.20 |
| DLBCL | Chapuy cohort | NA |
Mutation pattern and selective pressure estimates
| Entity | Missense dN/dS | Nonsense dN/dS | Q value |
|---|---|---|---|
| BL | 0.6966 | 2.2820 | 1.0000 |
| FL | 1.1485 | 1.2228 | 1.0000 |
| DLBCL | 0.0000 | 0.0000 | 0.9986 |
aSHM regions
| chr_name | hg19_start | hg19_end | region | regulatory_comment |
|---|---|---|---|---|
| chr4 | 25861094 | 25868788 | TSS | NA |
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Expression
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