Overview
Non-coding mutations in the promoter of this gene have been described in MCL.
Relevance tier by entity
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Mutation incidence in large patient cohorts (GAMBL reanalysis)
MCL
| pathology | Collection | N | mutated | Incidence | CI |
|---|---|---|---|---|---|
| MCL | GAMBL | 160 | 0 | 0 | [0,0] |
| MCL | BC_MCL | 103 | 0 | 0 | [0,0] |
| MCL | Barcelona | 57 | 0 | 0 | [0,0] |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 0.000 | 0 |
| DLBCL | No | No | 1.429 | 0 |
| FL | No | No | 0.000 | 0 |
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Expression
History
References
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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