UBE2A

History

%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%% timeline title Publication timing 2015-02-12 : Reichel : PMBL 2017-10-10 : Reddy : DLBCL

Relevance tier by entity

Entity Tier Description
PMBL 1 high-confidence PMBL/cHL/GZL genereichelFlowSortingExome2015a?
DLBCL 1 high-confidence DLBCL genelohrDiscoveryPrioritizationSomatic2012a?

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 4.21
DLBCL Schmitz cohort 7.02
DLBCL Reddy cohort 3.90
DLBCL Chapuy cohort 4.70

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 0.000 0
DLBCL No Yes 26.609 0
FL No No 51.360 0

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

UBE2A Expression

References