VMA21

Relevance tier by entity

Entity Tier Description
FL 1 high-confidence FL gene

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
FL GAMBL genomes 5.08

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 0.000 0.000
DLBCL No No 3.430 81.281
FL No Yes 25.632 598.612

[!NOTE] First described in FL in 2021 by Hübschmann D

View coding variants in ProteinPaint hg19 or hg38

image

View all variants in GenomePaint hg19 or hg38

image ## VMA21 Expression image