WDFY3
History
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timeline
title Publication timing
2013-08-15 : Morin : DLBCL
## Relevance
tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in DLBCL not firmly established |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 4.21 |
| DLBCL | Schmitz cohort | 8.30 |
| DLBCL | Reddy cohort | 4.70 |
| DLBCL | Chapuy cohort | 7.26 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 2.696 | 0.000 |
| DLBCL | No | No | 1.207 | 3.494 |
| FL | No | No | 2.069 | 0.000 |
[!NOTE] First described in DLBCL in 2013 by Morin RD
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
## WDFY3
Expression 
## References 1.
Morin RD, Mungall K, Pleasance E, Mungall AJ, Goya R, Huff RD, Scott DW,
Ding J, Roth A, Chiu R, Corbett RD, Chan FC, Mendez-Lago M, Trinh DL,
Bolger-Munro M, Taylor G, Hadj Khodabakhshi A, Ben-Neriah S, Pon J,
Meissner B, Woolcock B, Farnoud N, Rogic S, Lim EL, Johnson NA, Shah S,
Jones S, Steidl C, Holt R, Birol I, Moore R, Connors JM, Gascoyne RD,
Marra MA. Mutational and structural analysis of diffuse large B-cell
lymphoma using whole-genome sequencing. Blood. 2013 Aug
15;122(7):1256–1265. PMCID: PMC3744992
