[ZBTB7A]
Mutation tier
| Entity | Tier |
|---|---|
| BL | 2 |
| DLBCL | 2 |
Mutation incidence
| Entity | study | frequency (%) |
|---|---|---|
| BL | GAMBL genomes+capture | 3.0 |
| BL | Thomas cohort | NA |
| BL | Panea cohort | NA |
| DLBCL | GAMBL genomes | 1.8 |
| DLBCL | Schmitz cohort | 1.5 |
| DLBCL | Reddy cohort | 1.3 |
| DLBCL | Chapuy cohort | 1.7 |
Mutation pattern
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 4.693 | 0 |
| DLBCL | No | No | 1.625 | 0 |
| FL | No | No | 0.000 | 0 |
[!NOTE] First described in BL in 2022 by Burkhardt B. First described in DLBCL in 2017 by Reddy A
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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