ZBTB7A
History
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in BL not firmly establishedburkhardtClinicalRelevanceMolecular2022b? |
 |
2-F | failed QC |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| BL | GAMBL genomes+capture | 3.00 |
| BL | Thomas cohort | NA |
| BL | Panea cohort | NA |
| DLBCL | GAMBL genomes | 1.72 |
| DLBCL | Schmitz cohort | 1.49 |
| DLBCL | Reddy cohort | 1.30 |
| DLBCL | Chapuy cohort | 1.71 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 4.693 | 0 |
| DLBCL | No | No | 1.625 | 0 |
| FL | No | No | 0.000 | 0 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
ZBTB7A Expression
Representative Mutation
Rating ★ ☆ ☆
☆ ☆
All Mutations
Reddy_2060T Reddy_2142T Reddy_2158T Reddy_2226T Reddy_2600T Reddy_2626T Reddy_2707T Reddy_2772T Reddy_2884T Reddy_2891T Reddy_2912T Reddy_2918T Reddy_2939T Reddy_2956T Reddy_3385T Reddy_3419T Reddy_3454T Reddy_3468T Reddy_3474T Reddy_3483T Reddy_3498T Reddy_3504T Reddy_3562T Reddy_3590T Reddy_3607T Reddy_3611T Reddy_3616T Reddy_3648T Reddy_3655T Reddy_3665T Reddy_3700T Reddy_3715T Reddy_3787T Reddy_3838T Reddy_3859T Reddy_3923T Reddy_3986T Reddy_3997T Reddy_648T
References
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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