ZNF292
History
| Entity | Tier | Description |
|---|---|---|
 |
1 | high-confidence DLBCL gene |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 5.35 |
| DLBCL | Schmitz cohort | 6.38 |
| DLBCL | Reddy cohort | 4.30 |
| DLBCL | Chapuy cohort | 5.98 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 1.036 | 2.462 |
| DLBCL | No | No | 1.272 | 11.022 |
| FL | No | No | 2.049 | 0.000 |
[!NOTE] First described in DLBCL in 2013 by Zhang J
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
## ZNF292
Expression 
## References 1.
Zhang J, Grubor V, Love CL, Banerjee A, Richards KL, Mieczkowski PA,
Dunphy C, Choi W, Au WY, Srivastava G, Lugar PL, Rizzieri DA, Lagoo AS,
Bernal-Mizrachi L, Mann KP, Flowers C, Naresh K, Evens A, Gordon LI,
Czader M, Gill JI, Hsi ED, Liu Q, Fan A, Walsh K, Jima D, Smith LL,
Johnson AJ, Byrd JC, Luftig MA, Ni T, Zhu J, Chadburn A, Levy S, Dunson
D, Dave SS. Genetic heterogeneity of diffuse large B-cell lymphoma. 2013
Jan;
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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