FOXC1.md
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@@ -35,7 +35,11 @@ View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/F
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![image](images/proteinpaint/FOXC1.svg)
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-## References
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-1. *Schmitz R, Wright GW, Huang DW, Johnson CA, Phelan JD, Wang JQ, Roulland S, Kasbekar M, Young RM, Shaffer AL, Hodson DJ, Xiao W, Yu X, Yang Y, Zhao H, Xu W, Liu X, Zhou B, Du W, Chan WC, Jaffe ES, Gascoyne RD, Connors JM, Campo E, Lopez-Guillermo A, Rosenwald A, Ott G, Delabie J, Rimsza LM, Tay Kuang Wei K, Zelenetz AD, Leonard JP, Bartlett NL, Tran B, Shetty J, Zhao Y, Soppet DR, Pittaluga S, Wilson WH, Staudt LM. Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma. N Engl J Med. 2018 Apr 12;378(15):1396-1407. doi: 10.1056/NEJMoa1801445. PMID: 29641966; PMCID: PMC6010183.*
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+
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## FOXC1 Expression
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![image](images/gene_expression/FOXC1_by_pathology.svg)
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+
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+## References
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+1. *Schmitz R, Wright GW, Huang DW, Johnson CA, Phelan JD, Wang JQ, Roulland S, Kasbekar M, Young RM, Shaffer AL, Hodson DJ, Xiao W, Yu X, Yang Y, Zhao H, Xu W, Liu X, Zhou B, Du W, Chan WC, Jaffe ES, Gascoyne RD, Connors JM, Campo E, Lopez-Guillermo A, Rosenwald A, Ott G, Delabie J, Rimsza LM, Tay Kuang Wei K, Zelenetz AD, Leonard JP, Bartlett NL, Tran B, Shetty J, Zhao Y, Soppet DR, Pittaluga S, Wilson WH, Staudt LM. Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma. N Engl J Med. 2018 Apr 12;378(15):1396-1407. doi: 10.1056/NEJMoa1801445. PMID: 29641966; PMCID: PMC6010183.*
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+<!-- FLAGGED FOR TIER 2 -->
HLA-DMA.md
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@@ -1,5 +1,5 @@
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# HLA-DMA
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-
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+## Overview
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Mutations in this gene are relatively rare in DLBCL overall. *Without further support, this gene may be migrated to Tier 2.*
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## Relevance tier by entity
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View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/HLA-DMA.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/HLA-DMA_hg38.html)
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![image](images/proteinpaint/HLA-DMA.svg)
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+
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## HLA-DMA Expression
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![image](images/gene_expression/HLA-DMA_by_pathology.svg)
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+
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+<!-- FLAGGED FOR TIER 2 -->
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+
HLA-DQA1.md
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@@ -28,5 +28,9 @@ Mutations in this gene are relatively rare in DLBCL overall. *Without further su
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> [!NOTE]
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> First described in DLBCL in 2021 by [Hübschmann D](https://pubmed.ncbi.nlm.nih.gov/33953289)
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+
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## HLA-DQA1 Expression
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![image](images/gene_expression/HLA-DQA1_by_pathology.svg)
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+
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+<!-- FLAGGED FOR TIER 2 -->
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+<!-- ORPHANED -->
IL16.md
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@@ -34,5 +34,9 @@ View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAM
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View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/IL16.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/IL16_hg38.html)
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![image](images/proteinpaint/IL16.svg)
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+
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## IL16 Expression
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![image](images/gene_expression/IL16_by_pathology.svg)
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+
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+<!-- FLAGGED FOR TIER 2 -->
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+
LYN.md
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@@ -36,3 +36,5 @@ View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/L
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![image](images/proteinpaint/LYN.svg)
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## LYN Expression
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![image](images/gene_expression/LYN_by_pathology.svg)
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+
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+<!-- FLAGGED FOR TIER 2 -->
NCOR2.md
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@@ -46,5 +46,8 @@ View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAM
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View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/NCOR2.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/NCOR2_hg38.html)
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![image](images/proteinpaint/NCOR2.svg)
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+
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## NCOR2 Expression
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![image](images/gene_expression/NCOR2_by_pathology.svg)
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+
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+<!-- FLAGGED FOR TIER 2 -->
NFKB1.md
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@@ -43,5 +43,8 @@ View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAM
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View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/NFKB1.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/NFKB1_hg38.html)
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![image](images/proteinpaint/NFKB1.svg)
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+
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## NFKB1 Expression
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![image](images/gene_expression/NFKB1_by_pathology.svg)
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+
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+<!-- FLAGGED FOR TIER 2 -->