07b2992fa8d867353fb55385722c76107d7f7729
CD58.md
| ... | ... | @@ -38,15 +38,7 @@ timeline |
| 38 | 38 | |
| 39 | 39 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 40 | 40 | |
| 41 | -|Entity|source |frequency (%)| |
|
| 42 | -|:------:|:---------------------:|:-------------:| |
|
| 43 | -|DLBCL |GAMBL genomes | 7.84 | |
|
| 44 | -|DLBCL |Schmitz cohort |10.00 | |
|
| 45 | -|DLBCL |Reddy cohort | 2.80 | |
|
| 46 | -|DLBCL |Chapuy cohort | 6.84 | |
|
| 47 | -|BL |GAMBL genomes+capture| 0.92 | |
|
| 48 | -|BL |Thomas cohort | 0.80 | |
|
| 49 | -|BL |Panea cohort | 2.00 | |
|
| 41 | +[[include:DLBCL_CD58.md]] |
|
| 50 | 42 | |
| 51 | 43 | ## Mutation pattern and selective pressure estimates |
| 52 | 44 |
CD70.md
| ... | ... | @@ -37,16 +37,8 @@ timeline |
| 37 | 37 | |
| 38 | 38 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 39 | 39 | |
| 40 | -|Entity|source |frequency (%)| |
|
| 41 | -|:------:|:---------------------:|:-------------:| |
|
| 42 | -|DLBCL |GAMBL genomes |5.54 | |
|
| 43 | -|DLBCL |Schmitz cohort |9.36 | |
|
| 44 | -|DLBCL |Reddy cohort |6.91 | |
|
| 45 | -|DLBCL |Chapuy cohort |7.69 | |
|
| 46 | -|FL |GAMBL genomes |1.15 | |
|
| 47 | -|BL |GAMBL genomes+capture|0.92 | |
|
| 48 | -|BL |Thomas cohort |0.40 | |
|
| 49 | -|BL |Panea cohort |3.00 | |
|
| 40 | +[[include:DLBCL_CD70.md]] |
|
| 41 | +[[include:FL_CD70.md]] |
|
| 50 | 42 | |
| 51 | 43 | ## Mutation pattern and selective pressure estimates |
| 52 | 44 |
CD79B.md
| ... | ... | @@ -36,22 +36,14 @@ timeline |
| 36 | 36 | |
| 37 | 37 | |Entity|Tier|Description | |
| 38 | 38 | |:------:|:----:|--------------------------------------| |
| 39 | -| |1-EE |high-confidence DLBCL gene with functional evidence[@davisChronicActiveBcellreceptor2010] [@morinFrequentMutationHistonemodifying2011]| |
|
| 39 | +| |1 |high-confidence DLBCL gene with functional evidence[@davisChronicActiveBcellreceptor2010] [@morinFrequentMutationHistonemodifying2011]| |
|
| 40 | 40 | | |2 |relevance in FL not firmly established| |
| 41 | 41 | | |3 |Retired, Failed QC[@paneaWholeGenomeLandscape2019]| |
| 42 | 42 | |
| 43 | 43 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 44 | 44 | |
| 45 | -|Entity|source |frequency (%)| |
|
| 46 | -|:------:|:---------------------:|:-------------:| |
|
| 47 | -|BL |GAMBL genomes+capture| 1.39 | |
|
| 48 | -|BL |Thomas cohort | 0.00 | |
|
| 49 | -|BL |Panea cohort | 4.00 | |
|
| 50 | -|DLBCL |GAMBL genomes | 9.94 | |
|
| 51 | -|DLBCL |Schmitz cohort |14.89 | |
|
| 52 | -|DLBCL |Reddy cohort | 8.31 | |
|
| 53 | -|DLBCL |Chapuy cohort |15.38 | |
|
| 54 | -|FL |GAMBL genomes | 2.77 | |
|
| 45 | +[[include:DLBCL_CD79B.md]] |
|
| 46 | +[[include:FL_CD79B.md]] |
|
| 55 | 47 | |
| 56 | 48 | ## Mutation pattern and selective pressure estimates |
| 57 | 49 |