0856aed580aec342fd3652ea37f8b29953ff844e
BCL6.md
| ... | ... | @@ -22,9 +22,9 @@ timeline |
| 22 | 22 | |
| 23 | 23 | |Entity|Tier|Description | |
| 24 | 24 | |:------:|:----:|--------------------------------------| |
| 25 | -| |2-a | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@loveGeneticLandscapeMutations2012]| |
|
| 26 | -| |1-a | aSHM target and high-confidence DLBCL gene [@morinFrequentMutationHistonemodifying2011]| |
|
| 27 | -| |1-a | aSHM target and high-confidence FL gene | |
|
| 25 | +| |2 | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@loveGeneticLandscapeMutations2012]| |
|
| 26 | +| |1-EE[@balSuperenhancerHypermutationAlters2022] | aSHM target and high-confidence DLBCL gene [@morinFrequentMutationHistonemodifying2011]| |
|
| 27 | +| |1 | aSHM target and high-confidence FL gene | |
|
| 28 | 28 | |
| 29 | 29 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 30 | 30 |
DLBCL_genes.md
| ... | ... | @@ -22,7 +22,7 @@ link-citations: true |
| 22 | 22 | |[B2M](B2M)|1-EE|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@pararajalingamCodingNoncodingDrivers2020; @reichelFlowSortingExome2015a]| |
| 23 | 23 | |[BCL10](BCL10)|1-EE|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@spinaGeneticsNodalMarginal2016b; @russler-germainMutationsAssociatedProgression2023b]| |
| 24 | 24 | |[BCL2](BCL2)|1-EE|[Tanaka et al](papers/tanakaFrequentIncidenceSomatic1992)[@tanakaFrequentIncidenceSomatic1992]|[@morinFrequentMutationHistonemodifying2011; @burkhardtClinicalRelevanceMolecular2022b; @sarkozyMutationalLandscapeGray2021a]| |
| 25 | -|[BCL6](BCL6)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012]| |
|
| 25 | +|[BCL6](BCL6)|1-EE|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012]| |
|
| 26 | 26 | |[BCL7A](BCL7A)|1|[Arthur et al](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|[@krysiakRecurrentSomaticMutations2017b; @grandeGenomewideDiscoverySomatic2019; @reichelFlowSortingExome2015a]| |
| 27 | 27 | |[BIRC6](BIRC6)|1|[Reddy et al](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@sarkozyMutationalLandscapeGray2021a]| |
| 28 | 28 | |[BRAF](BRAF)|1|[Tiacci et al](papers/tiacciBRAFMutationsHairycell2011a)[@tiacciBRAFMutationsHairycell2011a]|[@loveGeneticLandscapeMutations2012]| |