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IL16.md
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| 7 | 7 | |
| 8 | 8 | ## Overview |
| 9 | 9 | The IL16 gene, which encodes a pro-inflammatory cytokine, plays a role in immune responses. IL-16 is highly expressed in the activated B-cell-like (ABC) subtype of DLBCL compared to the germinal center B-cell-like (GCB) subtype. The role of mutations in lymphomagenesis is not understood. Overall, the mutation rate of IL16 is relatively low in DLBCL. *Without further support, this gene may be migrated to Tier 2.* |
| 10 | -## History |
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| 11 | 10 | |
| 12 | 11 | ## Relevance tier by entity |
| 13 | 12 |