Changes in 133d1e1: test

				test_FL_genes.md
			
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          +---

          +title: 'FL genes'

          +bibliography: 'morinlab.bib'

          +csl: 'NLM.csl'

          +link-citations: true

          +---

          +

          +## Origins of FL genes

          +

          +![](FL_sankey-1.svg)

          +

          +## Tier 1 FL genes

          +

          +### *66 total*

          +

          +|Gene|Tier| First FL evidence | Other entities |

          +|:-:|:-:|:-|:-|

          +|[ACTB](ACTB)|1, aSHM||[@lohrDiscoveryPrioritizationSomatic2012a; @wienandGenomicAnalysesFlowsorted2019b]|

          +|[ARID1A](ARID1A)|1|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@wienandGenomicAnalysesFlowsorted2019b; @rossiCodingGenomeSplenic2012c; @zhangGeneticHeterogeneityDiffuse2013; @loveGeneticLandscapeMutations2012]|

          +|[ATP6AP1](ATP6AP1)|1|[Study Page](papers/okosunRecurrentMTORC1activatingRRAGC2016a)[@okosunRecurrentMTORC1activatingRRAGC2016a]||

          +|[ATP6V1B2](ATP6V1B2)|1|[Study Page](papers/okosunRecurrentMTORC1activatingRRAGC2016a)[@okosunRecurrentMTORC1activatingRRAGC2016a]||

          +|[B2M](B2M)|1|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@pararajalingamCodingNoncodingDrivers2020; @reichelFlowSortingExome2015a]|

          +|[BCL2](BCL2)|1, aSHM|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@tanakaFrequentIncidenceSomatic1992; @burkhardtClinicalRelevanceMolecular2022b; @sarkozyMutationalLandscapeGray2021a]|

          +|[BCL6](BCL6)|1, aSHM||[@loveGeneticLandscapeMutations2012; @morinFrequentMutationHistonemodifying2011]|

          +|[BCL7A](BCL7A)|1, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@grandeGenomewideDiscoverySomatic2019; @arthurGenomewideDiscoverySomatic2018; @reichelFlowSortingExome2015a]|

          +|[BIRC6](BIRC6)|1||[@sarkozyMutationalLandscapeGray2021a; @reddyGeneticFunctionalDrivers2017]|

          +|[BTG1](BTG1)|1, aSHM||[@sarkozyMutationalLandscapeGray2021a; @morinFrequentMutationHistonemodifying2011; @burkhardtClinicalRelevanceMolecular2022b]|

          +|[BTG2](BTG2)|1, aSHM|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012]|

          +|[BTK](BTK)|1|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@albuquerqueEnhancingKnowledgeDiscovery2017a]|

          +|[CARD11](CARD11)|1|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@lenzOncogenicCARD11Mutations2008; @paneaWholeGenomeLandscape2019; @wuGeneticHeterogeneityPrimary2016; @yanBCRTLRSignaling2012a]|

          +|[CCND3](CCND3)|1|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@richterRecurrentMutationID32012a; @jalladesExomeSequencingIdentifies2017; @deschGenotypingCirculatingTumor2020]|

          +|[CD83](CD83)|1, aSHM|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@paneaWholeGenomeLandscape2019; @dunsCharacterizationDLBCLPMBL2021b; @morinMutationalStructuralAnalysis2013]|

          +|[CREBBP](CREBBP)|1|[Study Page](papers/pasqualucciInactivatingMutationsAcetyltransferase2011a)[@pasqualucciInactivatingMutationsAcetyltransferase2011a]|[@dunsCharacterizationDLBCLPMBL2021b; @parryWholeExomeSequencing2013; @loveGeneticLandscapeMutations2012]|

          +|[CTSS](CTSS)|1|[Study Page](papers/barariaCathepsinAlterationsInduce2020c)[@barariaCathepsinAlterationsInduce2020c]||

          +|[DTX1](DTX1)|1, aSHM||[@schmitzGeneticsPathogenesisDiffuse2018a; @gomezUltraDeepSequencingReveals2023; @loveGeneticLandscapeMutations2012; @rossiCodingGenomeSplenic2012c]|

          +|[EBF1](EBF1)|1, aSHM||[@reichelFlowSortingExome2015a; @bohleRoleEarlyBcell2013; @thomasGeneticSubgroupsInform2023]|

          +|[EEF1A1](EEF1A1)|1|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@reichelFlowSortingExome2015a]|

          +|[EP300](EP300)|1|[Study Page](papers/pasqualucciInactivatingMutationsAcetyltransferase2011a)[@pasqualucciInactivatingMutationsAcetyltransferase2011a]|[@paneaWholeGenomeLandscape2019; @rossiCodingGenomeSplenic2012c]|

          +|[EZH2](EZH2)|1|[Study Page](papers/morinSomaticMutationsAltering2010a)[@morinSomaticMutationsAltering2010a]|[@mottokIntegrativeGenomicAnalysis2019b; @loveGeneticLandscapeMutations2012]|

          +|[FAS](FAS)|1||[@schollMutationsRegionFAS2007; @spinaGeneticsNodalMarginal2016b]|

          +|[FOXO1](FOXO1)|1|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@dunsCharacterizationDLBCLPMBL2021b; @schmitzBurkittLymphomaPathogenesis2012]|

          +|[GNA13](GNA13)|1|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@reichelFlowSortingExome2015a; @loveGeneticLandscapeMutations2012]|

          +|[GNAI2](GNAI2)|1||[@morinMutationalStructuralAnalysis2013; @grandeGenomewideDiscoverySomatic2019]|

          +|[HIST1H1B](HIST1H1B)|1, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@chapuyMolecularSubtypesDiffuse2018b; @sarkozyMutationalLandscapeGray2021a]|

          +|[HIST1H1C](HIST1H1C)|1, aSHM|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019]|

          +|[HIST1H1D](HIST1H1D)|1, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@morinMutationalStructuralAnalysis2013; @jalladesExomeSequencingIdentifies2017]|

          +|[HIST1H1E](HIST1H1E)|1, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@grandeGenomewideDiscoverySomatic2019; @lohrDiscoveryPrioritizationSomatic2012a; @reichelFlowSortingExome2015a]|

          +|[HIST1H2AC](HIST1H2AC)|1, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@morinMutationalStructuralAnalysis2013]|

          +|[HIST1H2AG](HIST1H2AG)|1, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@morinMutationalStructuralAnalysis2013; @rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019]|

          +|[HIST1H2AM](HIST1H2AM)|1, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@paneaWholeGenomeLandscape2019]|

          +|[HIST1H2BC](HIST1H2BC)|1, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@lohrDiscoveryPrioritizationSomatic2012a; @mottokIntegrativeGenomicAnalysis2019b]|

          +|[HIST1H2BD](HIST1H2BD)|1, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]||

          +|[HIST1H2BG](HIST1H2BG)|1, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]||

          +|[HIST1H3B](HIST1H3B)|1, aSHM||[@reichelFlowSortingExome2015a; @lohrDiscoveryPrioritizationSomatic2012a]|

          +|[HIST1H3G](HIST1H3G)|1, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]||

          +|[HVCN1](HVCN1)|1|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]||

          +|[IRF4](IRF4)|1, aSHM||[@morinFrequentMutationHistonemodifying2011; @mottokIntegrativeGenomicAnalysis2019b]|

          +|[IRF8](IRF8)|1, aSHM|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019; @mottokIntegrativeGenomicAnalysis2019b]|

          +|[ITPKB](ITPKB)|1, aSHM||[@reichelFlowSortingExome2015a; @schmitzGeneticsPathogenesisDiffuse2018a]|

          +|[KLF2](KLF2)|1, aSHM||[@jalladesExomeSequencingIdentifies2017; @pasqualucciAnalysisCodingGenome2011; @deschGenotypingCirculatingTumor2020]|

          +|[KLHL6](KLHL6)|1, aSHM|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019; @ganapathiGeneticLandscapeDural2016]|

          +|[KMT2D](KMT2D)|1|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@beaLandscapeSomaticMutations2013; @rossiCodingGenomeSplenic2012c; @grandeGenomewideDiscoverySomatic2019; @deschGenotypingCirculatingTumor2020]|

          +|[LTB](LTB)|1, aSHM||[@paneaWholeGenomeLandscape2019; @deschGenotypingCirculatingTumor2020; @chapuyMolecularSubtypesDiffuse2018b]|

          +|[MAP2K1](MAP2K1)|1|[Study Page](papers/louissaintPediatrictypeNodalFollicular2016a)[@louissaintPediatrictypeNodalFollicular2016a]|[@shinBRAFV600EMAP2K12015]|

          +|[MEF2B](MEF2B)|1, aSHM|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@beaLandscapeSomaticMutations2013]|

          +|[MEF2C](MEF2C)|1, aSHM||[@arthurGenomewideDiscoverySomatic2018]|

          +|[PCLO](PCLO)|1||[@lohrDiscoveryPrioritizationSomatic2012a]|

          +|[PIM1](PIM1)|1, aSHM||[@dunsCharacterizationDLBCLPMBL2021b; @pasqualucciHypermutationMultipleProtooncogenes2001a; @burkhardtClinicalRelevanceMolecular2022b]|

          +|[POU2AF1](POU2AF1)|1|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]||

          +|[POU2F2](POU2F2)|1|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@lohrDiscoveryPrioritizationSomatic2012a]|

          +|[PTPRD](PTPRD)|1||[@spinaGeneticsNodalMarginal2016b]|

          +|[RRAGC](RRAGC)|1||[@okosunRecurrentMTORC1activatingRRAGC2016a]|

          +|[S1PR2](S1PR2)|1, aSHM||[@muppidiLossSignalingGa132014b; @morinFrequentMutationHistonemodifying2011]|

          +|[SGK1](SGK1)|1, aSHM|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@dunsCharacterizationDLBCLPMBL2021b]|

          +|[SMARCA4](SMARCA4)|1|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@richterRecurrentMutationID32012a; @nadeuGenomicEpigenomicInsights2020b; @lohrDiscoveryPrioritizationSomatic2012a]|

          +|[SOCS1](SOCS1)|1, aSHM||[@morinFrequentMutationHistonemodifying2011; @wenigerMutationsTumorSuppressor2006a]|

          +|[STAT6](STAT6)|1|[Study Page](papers/yildizActivatingSTAT6Mutations2015c)[@yildizActivatingSTAT6Mutations2015c]|[@ritzRecurrentMutationsSTAT62009a]|

          +|[TBL1XR1](TBL1XR1)|1||[@lohrDiscoveryPrioritizationSomatic2012a; @rossiCodingGenomeSplenic2012c]|

          +|[TMSB4X](TMSB4X)|1, aSHM||[@albuquerqueEnhancingKnowledgeDiscovery2017a]|

          +|[TNFAIP3](TNFAIP3)|1||[@rossiAlterationBIRC3Multiple2011a; @compagnoMutationsMultipleGenes2009a; @schmitzTNFAIP3A20Tumor2009a]|

          +|[TNFRSF14](TNFRSF14)|1|[Study Page](papers/cheungAcquiredTNFRSF14Mutations2010a)[@cheungAcquiredTNFRSF14Mutations2010a]|[@spinaGeneticsNodalMarginal2016b; @morinFrequentMutationHistonemodifying2011]|

          +|[TP53](TP53)|1|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@rossiCodingGenomeSplenic2012c; @beaLandscapeSomaticMutations2013; @tiacciPervasiveMutationsJAKSTAT2018b; @wildaInactivationARFMDM2p53Pathway2004; @lohrDiscoveryPrioritizationSomatic2012a]|

          +|[VMA21](VMA21)|1|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]||

          +

          +## Tier 2 FL genes

          +

          +### *50 total*

          +

          +|Gene|Tier| First FL evidence | Other entities |

          +|:-:|:-:|:-|:-|

          +|[ABL2](ABL2)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[ACTG1](ACTG1)|2, aSHM|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@spinaGeneticsNodalMarginal2016b; @deschGenotypingCirculatingTumor2020]|

          +|[ATP6V1A](ATP6V1A)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]||

          +|[BCL10](BCL10)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@spinaGeneticsNodalMarginal2016b; @morinFrequentMutationHistonemodifying2011]|

          +|[CD70](CD70)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@morinFrequentMutationHistonemodifying2011]|

          +|[CD79B](CD79B)|2||[@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]|

          +|[CDC42BPB](CDC42BPB)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@spinaGeneticsNodalMarginal2016b]|

          +|[CILP](CILP)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[CPNE8](CPNE8)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]||

          +|[CXCR4](CXCR4)|2, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@paneaWholeGenomeLandscape2019; @khodabakhshiRecurrentTargetsAberrant2012]|

          +|[CYP2A6](CYP2A6)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[DDX3X](DDX3X)|2||[@schmitzGeneticsPathogenesisDiffuse2018a; @mottokIntegrativeGenomicAnalysis2019b; @schmitzBurkittLymphomaPathogenesis2012]|

          +|[DHX15](DHX15)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]||

          +|[DUSP2](DUSP2)|2, aSHM||[@dunsCharacterizationDLBCLPMBL2021b; @lohrDiscoveryPrioritizationSomatic2012a]|

          +|[EGR1](EGR1)|2|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@rossiCodingGenomeSplenic2012c; @reichelFlowSortingExome2015a]|

          +|[FZR1](FZR1)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]||

          +|[GBP7](GBP7)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[GRM6](GRM6)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[HIST1H2BM](HIST1H2BM)|2, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]||

          +|[HIST1H3I](HIST1H3I)|2, aSHM|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@paneaWholeGenomeLandscape2019]|

          +|[HLA-B](HLA-B)|2||[@lohrDiscoveryPrioritizationSomatic2012a; @wienandGenomicAnalysesFlowsorted2019b]|

          +|[HNRNPD](HNRNPD)|2|||

          +|[IGLL5](IGLL5)|2, aSHM|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@deschGenotypingCirculatingTumor2020; @paneaWholeGenomeLandscape2019]|

          +|[JUP](JUP)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]||

          +|[KIR3DL1](KIR3DL1)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[LAPTM5](LAPTM5)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]||

          +|[MAGEC1](MAGEC1)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[MAP7D1](MAP7D1)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[MGEA5](MGEA5)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]||

          +|[MKI67](MKI67)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@schmitzBurkittLymphomaPathogenesis2012]|

          +|[MYC](MYC)|2, aSHM||[@pasqualucciHypermutationMultipleProtooncogenes2001a; @jalladesExomeSequencingIdentifies2017; @johnstonCmycHypermutationBurkitt1992; @dunsCharacterizationDLBCLPMBL2021b]|

          +|[MYCBP2](MYCBP2)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]||

          +|[MYD88](MYD88)|2||[@yanBCRTLRSignaling2012a; @ngoOncogenicallyActiveMYD882011a]|

          +|[NFKBIA](NFKBIA)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@wienandGenomicAnalysesFlowsorted2019b; @lakeMutationsNFKBIAEncoding2009]|

          +|[OR8H2](OR8H2)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[P2RY8](P2RY8)|2||[@muppidiLossSignalingGa132014b; @lohrDiscoveryPrioritizationSomatic2012a]|

          +|[PDS5B](PDS5B)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@morinMutationalStructuralAnalysis2013]|

          +|[PPP4C](PPP4C)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]||

          +|[PRKDC](PRKDC)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@schmitzGeneticsPathogenesisDiffuse2018a]|

          +|[PZP](PZP)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[RBM6](RBM6)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]||

          +|[SESN1](SESN1)|2|[Study Page](papers/oricchioGeneticEpigeneticInactivation2017b)[@oricchioGeneticEpigeneticInactivation2017b]||

          +|[SHROOM3](SHROOM3)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[SRRM2](SRRM2)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@morinMutationalStructuralAnalysis2013]|

          +|[STAB2](STAB2)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[TMEM30A](TMEM30A)|2|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]||

          +|[TPP1](TPP1)|2|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]||

          +|[XIRP2](XIRP2)|2|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]||

          +|[ZC3H12A](ZC3H12A)|2||[@arthurGenomewideDiscoverySomatic2018]|

          +|[ZNF608](ZNF608)|2|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@zhangGeneticHeterogeneityDiffuse2013]|

          +

          +

          +# References

...	...	@@ -0,0 +1,143 @@
	1	+---
	2	+title: 'FL genes'
	3	+bibliography: 'morinlab.bib'
	4	+csl: 'NLM.csl'
	5	+link-citations: true
	6	+---
	7	+
	8	+## Origins of FL genes
	9	+
	10	+![](FL_sankey-1.svg)
	11	+
	12	+## Tier 1 FL genes
	13	+
	14	+### 66 total
	15	+
	16	+\|Gene\|Tier\| First FL evidence \| Other entities \|
	17	+\|:-:\|:-:\|:-\|:-\|
	18	+\|[ACTB](ACTB)\|1, aSHM\|\|[@lohrDiscoveryPrioritizationSomatic2012a; @wienandGenomicAnalysesFlowsorted2019b]\|
	19	+\|[ARID1A](ARID1A)\|1\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@wienandGenomicAnalysesFlowsorted2019b; @rossiCodingGenomeSplenic2012c; @zhangGeneticHeterogeneityDiffuse2013; @loveGeneticLandscapeMutations2012]\|
	20	+\|[ATP6AP1](ATP6AP1)\|1\|[Study Page](papers/okosunRecurrentMTORC1activatingRRAGC2016a)[@okosunRecurrentMTORC1activatingRRAGC2016a]\|\|
	21	+\|[ATP6V1B2](ATP6V1B2)\|1\|[Study Page](papers/okosunRecurrentMTORC1activatingRRAGC2016a)[@okosunRecurrentMTORC1activatingRRAGC2016a]\|\|
	22	+\|[B2M](B2M)\|1\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@pararajalingamCodingNoncodingDrivers2020; @reichelFlowSortingExome2015a]\|
	23	+\|[BCL2](BCL2)\|1, aSHM\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@tanakaFrequentIncidenceSomatic1992; @burkhardtClinicalRelevanceMolecular2022b; @sarkozyMutationalLandscapeGray2021a]\|
	24	+\|[BCL6](BCL6)\|1, aSHM\|\|[@loveGeneticLandscapeMutations2012; @morinFrequentMutationHistonemodifying2011]\|
	25	+\|[BCL7A](BCL7A)\|1, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@grandeGenomewideDiscoverySomatic2019; @arthurGenomewideDiscoverySomatic2018; @reichelFlowSortingExome2015a]\|
	26	+\|[BIRC6](BIRC6)\|1\|\|[@sarkozyMutationalLandscapeGray2021a; @reddyGeneticFunctionalDrivers2017]\|
	27	+\|[BTG1](BTG1)\|1, aSHM\|\|[@sarkozyMutationalLandscapeGray2021a; @morinFrequentMutationHistonemodifying2011; @burkhardtClinicalRelevanceMolecular2022b]\|
	28	+\|[BTG2](BTG2)\|1, aSHM\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@loveGeneticLandscapeMutations2012]\|
	29	+\|[BTK](BTK)\|1\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@albuquerqueEnhancingKnowledgeDiscovery2017a]\|
	30	+\|[CARD11](CARD11)\|1\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@lenzOncogenicCARD11Mutations2008; @paneaWholeGenomeLandscape2019; @wuGeneticHeterogeneityPrimary2016; @yanBCRTLRSignaling2012a]\|
	31	+\|[CCND3](CCND3)\|1\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@richterRecurrentMutationID32012a; @jalladesExomeSequencingIdentifies2017; @deschGenotypingCirculatingTumor2020]\|
	32	+\|[CD83](CD83)\|1, aSHM\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|[@paneaWholeGenomeLandscape2019; @dunsCharacterizationDLBCLPMBL2021b; @morinMutationalStructuralAnalysis2013]\|
	33	+\|[CREBBP](CREBBP)\|1\|[Study Page](papers/pasqualucciInactivatingMutationsAcetyltransferase2011a)[@pasqualucciInactivatingMutationsAcetyltransferase2011a]\|[@dunsCharacterizationDLBCLPMBL2021b; @parryWholeExomeSequencing2013; @loveGeneticLandscapeMutations2012]\|
	34	+\|[CTSS](CTSS)\|1\|[Study Page](papers/barariaCathepsinAlterationsInduce2020c)[@barariaCathepsinAlterationsInduce2020c]\|\|
	35	+\|[DTX1](DTX1)\|1, aSHM\|\|[@schmitzGeneticsPathogenesisDiffuse2018a; @gomezUltraDeepSequencingReveals2023; @loveGeneticLandscapeMutations2012; @rossiCodingGenomeSplenic2012c]\|
	36	+\|[EBF1](EBF1)\|1, aSHM\|\|[@reichelFlowSortingExome2015a; @bohleRoleEarlyBcell2013; @thomasGeneticSubgroupsInform2023]\|
	37	+\|[EEF1A1](EEF1A1)\|1\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|[@reichelFlowSortingExome2015a]\|
	38	+\|[EP300](EP300)\|1\|[Study Page](papers/pasqualucciInactivatingMutationsAcetyltransferase2011a)[@pasqualucciInactivatingMutationsAcetyltransferase2011a]\|[@paneaWholeGenomeLandscape2019; @rossiCodingGenomeSplenic2012c]\|
	39	+\|[EZH2](EZH2)\|1\|[Study Page](papers/morinSomaticMutationsAltering2010a)[@morinSomaticMutationsAltering2010a]\|[@mottokIntegrativeGenomicAnalysis2019b; @loveGeneticLandscapeMutations2012]\|
	40	+\|[FAS](FAS)\|1\|\|[@schollMutationsRegionFAS2007; @spinaGeneticsNodalMarginal2016b]\|
	41	+\|[FOXO1](FOXO1)\|1\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@dunsCharacterizationDLBCLPMBL2021b; @schmitzBurkittLymphomaPathogenesis2012]\|
	42	+\|[GNA13](GNA13)\|1\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@reichelFlowSortingExome2015a; @loveGeneticLandscapeMutations2012]\|
	43	+\|[GNAI2](GNAI2)\|1\|\|[@morinMutationalStructuralAnalysis2013; @grandeGenomewideDiscoverySomatic2019]\|
	44	+\|[HIST1H1B](HIST1H1B)\|1, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@chapuyMolecularSubtypesDiffuse2018b; @sarkozyMutationalLandscapeGray2021a]\|
	45	+\|[HIST1H1C](HIST1H1C)\|1, aSHM\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@paneaWholeGenomeLandscape2019]\|
	46	+\|[HIST1H1D](HIST1H1D)\|1, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@morinMutationalStructuralAnalysis2013; @jalladesExomeSequencingIdentifies2017]\|
	47	+\|[HIST1H1E](HIST1H1E)\|1, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@grandeGenomewideDiscoverySomatic2019; @lohrDiscoveryPrioritizationSomatic2012a; @reichelFlowSortingExome2015a]\|
	48	+\|[HIST1H2AC](HIST1H2AC)\|1, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@morinMutationalStructuralAnalysis2013]\|
	49	+\|[HIST1H2AG](HIST1H2AG)\|1, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@morinMutationalStructuralAnalysis2013; @rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019]\|
	50	+\|[HIST1H2AM](HIST1H2AM)\|1, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@paneaWholeGenomeLandscape2019]\|
	51	+\|[HIST1H2BC](HIST1H2BC)\|1, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@lohrDiscoveryPrioritizationSomatic2012a; @mottokIntegrativeGenomicAnalysis2019b]\|
	52	+\|[HIST1H2BD](HIST1H2BD)\|1, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|\|
	53	+\|[HIST1H2BG](HIST1H2BG)\|1, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|\|
	54	+\|[HIST1H3B](HIST1H3B)\|1, aSHM\|\|[@reichelFlowSortingExome2015a; @lohrDiscoveryPrioritizationSomatic2012a]\|
	55	+\|[HIST1H3G](HIST1H3G)\|1, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|\|
	56	+\|[HVCN1](HVCN1)\|1\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|\|
	57	+\|[IRF4](IRF4)\|1, aSHM\|\|[@morinFrequentMutationHistonemodifying2011; @mottokIntegrativeGenomicAnalysis2019b]\|
	58	+\|[IRF8](IRF8)\|1, aSHM\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@paneaWholeGenomeLandscape2019; @mottokIntegrativeGenomicAnalysis2019b]\|
	59	+\|[ITPKB](ITPKB)\|1, aSHM\|\|[@reichelFlowSortingExome2015a; @schmitzGeneticsPathogenesisDiffuse2018a]\|
	60	+\|[KLF2](KLF2)\|1, aSHM\|\|[@jalladesExomeSequencingIdentifies2017; @pasqualucciAnalysisCodingGenome2011; @deschGenotypingCirculatingTumor2020]\|
	61	+\|[KLHL6](KLHL6)\|1, aSHM\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@paneaWholeGenomeLandscape2019; @ganapathiGeneticLandscapeDural2016]\|
	62	+\|[KMT2D](KMT2D)\|1\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@beaLandscapeSomaticMutations2013; @rossiCodingGenomeSplenic2012c; @grandeGenomewideDiscoverySomatic2019; @deschGenotypingCirculatingTumor2020]\|
	63	+\|[LTB](LTB)\|1, aSHM\|\|[@paneaWholeGenomeLandscape2019; @deschGenotypingCirculatingTumor2020; @chapuyMolecularSubtypesDiffuse2018b]\|
	64	+\|[MAP2K1](MAP2K1)\|1\|[Study Page](papers/louissaintPediatrictypeNodalFollicular2016a)[@louissaintPediatrictypeNodalFollicular2016a]\|[@shinBRAFV600EMAP2K12015]\|
	65	+\|[MEF2B](MEF2B)\|1, aSHM\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@beaLandscapeSomaticMutations2013]\|
	66	+\|[MEF2C](MEF2C)\|1, aSHM\|\|[@arthurGenomewideDiscoverySomatic2018]\|
	67	+\|[PCLO](PCLO)\|1\|\|[@lohrDiscoveryPrioritizationSomatic2012a]\|
	68	+\|[PIM1](PIM1)\|1, aSHM\|\|[@dunsCharacterizationDLBCLPMBL2021b; @pasqualucciHypermutationMultipleProtooncogenes2001a; @burkhardtClinicalRelevanceMolecular2022b]\|
	69	+\|[POU2AF1](POU2AF1)\|1\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|\|
	70	+\|[POU2F2](POU2F2)\|1\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@lohrDiscoveryPrioritizationSomatic2012a]\|
	71	+\|[PTPRD](PTPRD)\|1\|\|[@spinaGeneticsNodalMarginal2016b]\|
	72	+\|[RRAGC](RRAGC)\|1\|\|[@okosunRecurrentMTORC1activatingRRAGC2016a]\|
	73	+\|[S1PR2](S1PR2)\|1, aSHM\|\|[@muppidiLossSignalingGa132014b; @morinFrequentMutationHistonemodifying2011]\|
	74	+\|[SGK1](SGK1)\|1, aSHM\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@dunsCharacterizationDLBCLPMBL2021b]\|
	75	+\|[SMARCA4](SMARCA4)\|1\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@richterRecurrentMutationID32012a; @nadeuGenomicEpigenomicInsights2020b; @lohrDiscoveryPrioritizationSomatic2012a]\|
	76	+\|[SOCS1](SOCS1)\|1, aSHM\|\|[@morinFrequentMutationHistonemodifying2011; @wenigerMutationsTumorSuppressor2006a]\|
	77	+\|[STAT6](STAT6)\|1\|[Study Page](papers/yildizActivatingSTAT6Mutations2015c)[@yildizActivatingSTAT6Mutations2015c]\|[@ritzRecurrentMutationsSTAT62009a]\|
	78	+\|[TBL1XR1](TBL1XR1)\|1\|\|[@lohrDiscoveryPrioritizationSomatic2012a; @rossiCodingGenomeSplenic2012c]\|
	79	+\|[TMSB4X](TMSB4X)\|1, aSHM\|\|[@albuquerqueEnhancingKnowledgeDiscovery2017a]\|
	80	+\|[TNFAIP3](TNFAIP3)\|1\|\|[@rossiAlterationBIRC3Multiple2011a; @compagnoMutationsMultipleGenes2009a; @schmitzTNFAIP3A20Tumor2009a]\|
	81	+\|[TNFRSF14](TNFRSF14)\|1\|[Study Page](papers/cheungAcquiredTNFRSF14Mutations2010a)[@cheungAcquiredTNFRSF14Mutations2010a]\|[@spinaGeneticsNodalMarginal2016b; @morinFrequentMutationHistonemodifying2011]\|
	82	+\|[TP53](TP53)\|1\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|[@rossiCodingGenomeSplenic2012c; @beaLandscapeSomaticMutations2013; @tiacciPervasiveMutationsJAKSTAT2018b; @wildaInactivationARFMDM2p53Pathway2004; @lohrDiscoveryPrioritizationSomatic2012a]\|
	83	+\|[VMA21](VMA21)\|1\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|\|
	84	+
	85	+## Tier 2 FL genes
	86	+
	87	+### 50 total
	88	+
	89	+\|Gene\|Tier\| First FL evidence \| Other entities \|
	90	+\|:-:\|:-:\|:-\|:-\|
	91	+\|[ABL2](ABL2)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	92	+\|[ACTG1](ACTG1)\|2, aSHM\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|[@spinaGeneticsNodalMarginal2016b; @deschGenotypingCirculatingTumor2020]\|
	93	+\|[ATP6V1A](ATP6V1A)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|\|
	94	+\|[BCL10](BCL10)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|[@spinaGeneticsNodalMarginal2016b; @morinFrequentMutationHistonemodifying2011]\|
	95	+\|[CD70](CD70)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|[@morinFrequentMutationHistonemodifying2011]\|
	96	+\|[CD79B](CD79B)\|2\|\|[@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]\|
	97	+\|[CDC42BPB](CDC42BPB)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|[@spinaGeneticsNodalMarginal2016b]\|
	98	+\|[CILP](CILP)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	99	+\|[CPNE8](CPNE8)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|\|
	100	+\|[CXCR4](CXCR4)\|2, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@paneaWholeGenomeLandscape2019; @khodabakhshiRecurrentTargetsAberrant2012]\|
	101	+\|[CYP2A6](CYP2A6)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	102	+\|[DDX3X](DDX3X)\|2\|\|[@schmitzGeneticsPathogenesisDiffuse2018a; @mottokIntegrativeGenomicAnalysis2019b; @schmitzBurkittLymphomaPathogenesis2012]\|
	103	+\|[DHX15](DHX15)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|\|
	104	+\|[DUSP2](DUSP2)\|2, aSHM\|\|[@dunsCharacterizationDLBCLPMBL2021b; @lohrDiscoveryPrioritizationSomatic2012a]\|
	105	+\|[EGR1](EGR1)\|2\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@rossiCodingGenomeSplenic2012c; @reichelFlowSortingExome2015a]\|
	106	+\|[FZR1](FZR1)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|\|
	107	+\|[GBP7](GBP7)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	108	+\|[GRM6](GRM6)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	109	+\|[HIST1H2BM](HIST1H2BM)\|2, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|\|
	110	+\|[HIST1H3I](HIST1H3I)\|2, aSHM\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@paneaWholeGenomeLandscape2019]\|
	111	+\|[HLA-B](HLA-B)\|2\|\|[@lohrDiscoveryPrioritizationSomatic2012a; @wienandGenomicAnalysesFlowsorted2019b]\|
	112	+\|[HNRNPD](HNRNPD)\|2\|\|\|
	113	+\|[IGLL5](IGLL5)\|2, aSHM\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|[@deschGenotypingCirculatingTumor2020; @paneaWholeGenomeLandscape2019]\|
	114	+\|[JUP](JUP)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|\|
	115	+\|[KIR3DL1](KIR3DL1)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	116	+\|[LAPTM5](LAPTM5)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|\|
	117	+\|[MAGEC1](MAGEC1)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	118	+\|[MAP7D1](MAP7D1)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	119	+\|[MGEA5](MGEA5)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|\|
	120	+\|[MKI67](MKI67)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|[@schmitzBurkittLymphomaPathogenesis2012]\|
	121	+\|[MYC](MYC)\|2, aSHM\|\|[@pasqualucciHypermutationMultipleProtooncogenes2001a; @jalladesExomeSequencingIdentifies2017; @johnstonCmycHypermutationBurkitt1992; @dunsCharacterizationDLBCLPMBL2021b]\|
	122	+\|[MYCBP2](MYCBP2)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|\|
	123	+\|[MYD88](MYD88)\|2\|\|[@yanBCRTLRSignaling2012a; @ngoOncogenicallyActiveMYD882011a]\|
	124	+\|[NFKBIA](NFKBIA)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|[@wienandGenomicAnalysesFlowsorted2019b; @lakeMutationsNFKBIAEncoding2009]\|
	125	+\|[OR8H2](OR8H2)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	126	+\|[P2RY8](P2RY8)\|2\|\|[@muppidiLossSignalingGa132014b; @lohrDiscoveryPrioritizationSomatic2012a]\|
	127	+\|[PDS5B](PDS5B)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|[@morinMutationalStructuralAnalysis2013]\|
	128	+\|[PPP4C](PPP4C)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|\|
	129	+\|[PRKDC](PRKDC)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|[@schmitzGeneticsPathogenesisDiffuse2018a]\|
	130	+\|[PZP](PZP)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	131	+\|[RBM6](RBM6)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|\|
	132	+\|[SESN1](SESN1)\|2\|[Study Page](papers/oricchioGeneticEpigeneticInactivation2017b)[@oricchioGeneticEpigeneticInactivation2017b]\|\|
	133	+\|[SHROOM3](SHROOM3)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	134	+\|[SRRM2](SRRM2)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|[@morinMutationalStructuralAnalysis2013]\|
	135	+\|[STAB2](STAB2)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	136	+\|[TMEM30A](TMEM30A)\|2\|[Study Page](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]\|\|
	137	+\|[TPP1](TPP1)\|2\|[Study Page](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]\|\|
	138	+\|[XIRP2](XIRP2)\|2\|[Study Page](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]\|\|
	139	+\|[ZC3H12A](ZC3H12A)\|2\|\|[@arthurGenomewideDiscoverySomatic2018]\|
	140	+\|[ZNF608](ZNF608)\|2\|[Study Page](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]\|[@zhangGeneticHeterogeneityDiffuse2013]\|
	141	+
	142	+
	143	+# References