1d20b191838313e0c1ca022cb499ab1eb322be44
PMBL_genes.md
| ... | ... | @@ -11,7 +11,7 @@ link-citations: true |
| 11 | 11 | |
| 12 | 12 | ## Tier 1, high-confidence PMBL genes |
| 13 | 13 | |
| 14 | -### *74 total* |
|
| 14 | +### *46 total* |
|
| 15 | 15 | |
| 16 | 16 | |Gene|Summary| First PMBL study | Other entities | QC result | |
| 17 | 17 | |:-:|:--:|:-:|:-|:-| |
| ... | ... | @@ -32,16 +32,9 @@ link-citations: true |
| 32 | 32 | |[DUSP2](DUSP2)|Tier 1 GE[@dunsCharacterizationDLBCLPMBL2021], aSHM|[Duns et al](papers/dunsCharacterizationDLBCLPMBL2021)|[@drevalGeneticSubdivisionsFollicular2023; @lohrDiscoveryPrioritizationSomatic2012]|| |
| 33 | 33 | |[EBF1](EBF1)|Tier 1 GE[@reichelFlowSortingExome2015], FE[@ramirez-komoSpontaneousLossLineage2017], aSHM|[Reichel et al](papers/reichelFlowSortingExome2015)|[@bohleRoleEarlyBcell2013; @drevalGeneticSubdivisionsFollicular2023; @thomasGeneticSubgroupsInform2023]|| |
| 34 | 34 | |[EEF1A1](EEF1A1)|Tier 1 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)|[@chapuyMolecularSubtypesDiffuse2018; @hubschmannMutationalMechanismsShaping2021]|| |
| 35 | -|[ETS1](ETS1)|Tier 1 GE[@], aSHM||[@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]|| |
|
| 36 | -|[EWSR1](EWSR1)|Tier 1 GE[@]||[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 37 | 35 | |[EZH2](EZH2)|Tier 1 GE[@mottokIntegrativeGenomicAnalysis2019], FE[@sneeringerCoordinatedActivitiesWildtype2010]|[Mottok et al](papers/mottokIntegrativeGenomicAnalysis2019)|[@loveGeneticLandscapeMutations2012; @morinSomaticMutationsAltering2010]|| |
| 38 | -|[FAS](FAS)|Tier 1 GE[@], FE[@wangFasFADDDeathDomain2010]||[@morinFrequentMutationHistonemodifying2011; @schollMutationsRegionFAS2007; @spinaGeneticsNodalMarginal2016]|| |
|
| 39 | -|[FAT1](FAT1)|Tier 1 GE[@]||[@spinaGeneticsNodalMarginal2016]|| |
|
| 40 | -|[FAT4](FAT4)|Tier 1 GE[@]||[@morinMutationalStructuralAnalysis2013; @parryWholeExomeSequencing2013; @zhangGenomicLandscapeMantle2014]|| |
|
| 41 | 36 | |[GNA13](GNA13)|Tier 1 GE[@reichelFlowSortingExome2015], FE[@muppidiLossSignalingGa132014]|[Reichel et al](papers/reichelFlowSortingExome2015)|[@loveGeneticLandscapeMutations2012; @morinFrequentMutationHistonemodifying2011]|| |
| 42 | 37 | |[HIST1H1B](HIST1H1B)|Tier 1 GE[@sarkozyMutationalLandscapeGray2021], aSHM|[Sarkozy et al](papers/sarkozyMutationalLandscapeGray2021)|[@chapuyMolecularSubtypesDiffuse2018; @krysiakRecurrentSomaticMutations2017]|| |
| 43 | -|[HIST1H1C](HIST1H1C)|Tier 1 GE[@], aSHM||[@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]|| |
|
| 44 | -|[HIST1H1D](HIST1H1D)|Tier 1 GE[@], aSHM||[@jalladesExomeSequencingIdentifies2017; @krysiakRecurrentSomaticMutations2017; @morinMutationalStructuralAnalysis2013]|| |
|
| 45 | 38 | |[HIST1H1E](HIST1H1E)|Tier 1 GE[@reichelFlowSortingExome2015], aSHM|[Reichel et al](papers/reichelFlowSortingExome2015)|[@grandeGenomewideDiscoverySomatic2019; @krysiakRecurrentSomaticMutations2017; @lohrDiscoveryPrioritizationSomatic2012]|| |
| 46 | 39 | |[HLA-B](HLA-B)|Tier 1 GE[@wienandGenomicAnalysesFlowsorted2019], FE[@fangazioGeneticMechanismsHLAI2021]|[Wienand et al](papers/wienandGenomicAnalysesFlowsorted2019)|[@lohrDiscoveryPrioritizationSomatic2012]|| |
| 47 | 40 | |[IL4R](IL4R)|Tier 1 GE[@viganoSomaticIL4RMutations2018], FE[@viganoSomaticIL4RMutations2018], aSHM|[Vigano et al](papers/viganoSomaticIL4RMutations2018)|[@dunsCharacterizationDLBCLPMBL2021]|| |
| ... | ... | @@ -54,45 +47,24 @@ link-citations: true |
| 54 | 47 | |[MS4A1](MS4A1)|Tier 1 GE[@mottokIntegrativeGenomicAnalysis2019], FE[@rushtonGeneticEvolutionaryPatterns2020], aSHM|[Mottok et al](papers/mottokIntegrativeGenomicAnalysis2019)|[@rushtonGeneticEvolutionaryPatterns2020]|| |
| 55 | 48 | |[NFKBIA](NFKBIA)|Tier 1 GE[@wienandGenomicAnalysesFlowsorted2019], FE[@jungnickelClonalDeleteriousMutations2000]|[Wienand et al](papers/wienandGenomicAnalysesFlowsorted2019)|[@russler-germainMutationsAssociatedProgression2023; @thomasMutationalAnalysisIkappaBalpha2004]|| |
| 56 | 49 | |[NFKBIE](NFKBIE)|Tier 1 GE[@mansouriFrequentNFKBIEDeletions2016], FE[@mansouriFunctionalLossIkBe2015]|[Mansouri et al](papers/mansouriFrequentNFKBIEDeletions2016)|[@morinGeneticLandscapesRelapsed2016; @pararajalingamCodingNoncodingDrivers2020]|| |
| 57 | -|[OSBPL10](OSBPL10)|Tier 1 GE[@], aSHM||[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 58 | -|[P2RY8](P2RY8)|Tier 1 GE[@], FE[@muppidiLossSignalingGa132014]||[@drevalGeneticSubdivisionsFollicular2023; @lohrDiscoveryPrioritizationSomatic2012; @muppidiLossSignalingGa132014]|| |
|
| 59 | -|[PCLO](PCLO)|Tier 1 GE[@]||[@lohrDiscoveryPrioritizationSomatic2012]|| |
|
| 60 | -|[PHIP](PHIP)|Tier 1 GE[@]|||| |
|
| 61 | 50 | |[PIM1](PIM1)|Tier 1 GE[@dunsCharacterizationDLBCLPMBL2021], FE[@kuoRolePIM1Ibrutinibresistant2016], aSHM|[Duns et al](papers/dunsCharacterizationDLBCLPMBL2021)|[@burkhardtClinicalRelevanceMolecular2022; @drevalGeneticSubdivisionsFollicular2023; @pasqualucciHypermutationMultipleProtooncogenes2001]|| |
| 62 | 51 | |[PIM2](PIM2)|Tier 1 GE[@reichelFlowSortingExome2015], aSHM|[Reichel et al](papers/reichelFlowSortingExome2015)|[@reddyGeneticFunctionalDrivers2017]|| |
| 63 | -|[PRKDC](PRKDC)|Tier 1 GE[@]||[@hubschmannMutationalMechanismsShaping2021; @schmitzGeneticsPathogenesisDiffuse2018]|| |
|
| 64 | 52 | |[PTPN1](PTPN1)|Tier 1 GE[@gunawardanaRecurrentSomaticMutations2014]|[Gunawardana et al](papers/gunawardanaRecurrentSomaticMutations2014)||| |
| 65 | -|[PTPRD](PTPRD)|Tier 1 GE[@]||[@drevalGeneticSubdivisionsFollicular2023; @spinaGeneticsNodalMarginal2016]|| |
|
| 66 | -|[RHOA](RHOA)|Tier 1 GE[@], FE[@ohayreInactivatingMutationsGNA132016]||[@richterRecurrentMutationID32012; @zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 67 | -|[S1PR2](S1PR2)|Tier 1 GE[@], FE[@muppidiLossSignalingGa132014], aSHM||[@drevalGeneticSubdivisionsFollicular2023; @morinFrequentMutationHistonemodifying2011; @muppidiLossSignalingGa132014]|| |
|
| 68 | 53 | |[SGK1](SGK1)|Tier 1 GE[@dunsCharacterizationDLBCLPMBL2021], FE[@gaoSGK1MutationsDLBCL2021], aSHM|[Duns et al](papers/dunsCharacterizationDLBCLPMBL2021)|[@morinFrequentMutationHistonemodifying2011]|| |
| 69 | -|[SIN3A](SIN3A)|Tier 1 GE[@]||[@chapuyMolecularSubtypesDiffuse2018; @grandeGenomewideDiscoverySomatic2019; @rossiCodingGenomeSplenic2012]|| |
|
| 70 | -|[SMARCA2](SMARCA2)|Tier 1 GE[@]|||| |
|
| 71 | -|[SMARCA4](SMARCA4)|Tier 1 GE[@], FE[@fernandoFunctionalCharacterizationSMARCA42020]||[@krysiakRecurrentSomaticMutations2017; @nadeuGenomicEpigenomicInsights2020b; @reddyGeneticFunctionalDrivers2017; @richterRecurrentMutationID32012]|| |
|
| 72 | 54 | |[SOCS1](SOCS1)|Tier 1 GE[@wenigerMutationsTumorSuppressor2006], FE[@melznerBiallelicMutationSOCS12005], aSHM|[Weniger et al](papers/wenigerMutationsTumorSuppressor2006)|[@drevalGeneticSubdivisionsFollicular2023; @morinFrequentMutationHistonemodifying2011]|| |
| 73 | 55 | |[SPEN](SPEN)|Tier 1 GE[@sarkozyMutationalLandscapeGray2021]|[Sarkozy et al](papers/sarkozyMutationalLandscapeGray2021)|[@albuquerqueEnhancingKnowledgeDiscovery2017; @rossiCodingGenomeSplenic2012]|| |
| 74 | -|[STAT3](STAT3)|Tier 1 GE[@], FE[@huNovelMissenseM206K2013]||[@morinFrequentMutationHistonemodifying2011]|| |
|
| 75 | 56 | |[STAT6](STAT6)|Tier 1 GE[@ritzRecurrentMutationsSTAT62009], FE[@mentzPARP14NovelTarget2022]|[Ritz et al](papers/ritzRecurrentMutationsSTAT62009)|[@yildizActivatingSTAT6Mutations2015]|| |
| 76 | -|[TAP1](TAP1)|Tier 1 GE[@]||[@schmitzGeneticsPathogenesisDiffuse2018]|| |
|
| 77 | -|[TBL1XR1](TBL1XR1)|Tier 1 GE[@], FE[@venturuttiTBL1XR1MutationsDrive2020]||[@drevalGeneticSubdivisionsFollicular2023; @lohrDiscoveryPrioritizationSomatic2012; @rossiCodingGenomeSplenic2012]|| |
|
| 78 | -|[TCF3](TCF3)|Tier 1 GE[@]||[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 79 | -|[TET3](TET3)|Tier 1 GE[@]|||| |
|
| 80 | -|[TMSB4X](TMSB4X)|Tier 1 GE[@], aSHM||[@drevalGeneticSubdivisionsFollicular2023; @reddyGeneticFunctionalDrivers2017]|| |
|
| 81 | 57 | |[TNFAIP3](TNFAIP3)|Tier 1 GE[@schmitzTNFAIP3A20Tumor2009], FE[@compagnoMutationsMultipleGenes2009]|[Schmitz et al](papers/schmitzTNFAIP3A20Tumor2009)|[@compagnoMutationsMultipleGenes2009; @drevalGeneticSubdivisionsFollicular2023; @rossiAlterationBIRC3Multiple2011]|| |
| 82 | -|[TNFRSF1B](TNFRSF1B)|Tier 1 GE[@]|||| |
|
| 83 | 58 | |[TP53](TP53)|Tier 1 GE[@tiacciPervasiveMutationsJAKSTAT2018], FE[@katoUnderstandingFunctionstructureFunctionmutation2003]|[Tiacci et al](papers/tiacciPervasiveMutationsJAKSTAT2018)|[@beaLandscapeSomaticMutations2013; @morinFrequentMutationHistonemodifying2011; @rossiCodingGenomeSplenic2012; @wildaInactivationARFMDM2p53Pathway2004]|| |
| 84 | 59 | |[TRAF3](TRAF3)|Tier 1 GE[@ottoGeneticLesionsTRAF32012]|[Otto et al](papers/ottoGeneticLesionsTRAF32012)|[@pasqualucciAnalysisCodingGenome2011; @rossiAlterationBIRC3Multiple2011]|| |
| 85 | 60 | |[UBE2A](UBE2A)|Tier 1 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)|[@lohrDiscoveryPrioritizationSomatic2012]|| |
| 86 | -|[UBR5](UBR5)|Tier 1 GE[@]||[@albuquerqueEnhancingKnowledgeDiscovery2017; @pararajalingamCodingNoncodingDrivers2020]|| |
|
| 87 | -|[UNC5C](UNC5C)|Tier 1 GE[@]||[@lohrDiscoveryPrioritizationSomatic2012]|| |
|
| 88 | -|[VPS13B](VPS13B)|Tier 1 GE[@]|||| |
|
| 89 | 61 | |[WEE1](WEE1)|Tier 1 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)|[@schmitzGeneticsPathogenesisDiffuse2018]|| |
| 90 | 62 | |[XPO1](XPO1)|Tier 1 GE[@jardinRecurrentMutationsExportin2016], FE[@miloudiXPO1E571KMutationModifies2020]|[Jardin et al](papers/jardinRecurrentMutationsExportin2016)|[@mareschalWholeExomeSequencing2016]|| |
| 91 | 63 | |[ZFP36L1](ZFP36L1)|Tier 1 GE[@reichelFlowSortingExome2015], aSHM|[Reichel et al](papers/reichelFlowSortingExome2015)|[@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]|| |
| 92 | 64 | |
| 93 | 65 | ## Tier 2, low-confidence PMBL genes |
| 94 | 66 | |
| 95 | -### *84 total* |
|
| 67 | +### *112 total* |
|
| 96 | 68 | |
| 97 | 69 | |Gene|Summary| First PMBL study | Other entities | QC result | |
| 98 | 70 | |:-:|:--:|:-:|:-|:-| |
| ... | ... | @@ -115,12 +87,19 @@ link-citations: true |
| 115 | 87 | |[DNAH12](DNAH12)|Tier 2 GE[@wienandGenomicAnalysesFlowsorted2019]|[Wienand et al](papers/wienandGenomicAnalysesFlowsorted2019)||| |
| 116 | 88 | |[EGR1](EGR1)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)|[@krysiakRecurrentSomaticMutations2017; @rossiCodingGenomeSplenic2012]|| |
| 117 | 89 | |[EPHA7](EPHA7)|Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019]|[Mottok et al](papers/mottokIntegrativeGenomicAnalysis2019)|[@zhangGeneticHeterogeneityDiffuse2013]|| |
| 90 | +|[ETS1](ETS1)|Tier 2 GE, aSHM||[@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]|| |
|
| 91 | +|[EWSR1](EWSR1)|Tier 2 GE||[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 118 | 92 | |[EZR](EZR)|Tier 2 GE[@deschGenotypingCirculatingTumor2020], aSHM|[Desch et al](papers/deschGenotypingCirculatingTumor2020)||| |
| 93 | +|[FAS](FAS)|Tier 2 GE, FE[@wangFasFADDDeathDomain2010]||[@morinFrequentMutationHistonemodifying2011; @schollMutationsRegionFAS2007; @spinaGeneticsNodalMarginal2016]|| |
|
| 94 | +|[FAT1](FAT1)|Tier 2 GE||[@spinaGeneticsNodalMarginal2016]|| |
|
| 95 | +|[FAT4](FAT4)|Tier 2 GE||[@morinMutationalStructuralAnalysis2013; @parryWholeExomeSequencing2013; @zhangGenomicLandscapeMantle2014]|| |
|
| 119 | 96 | |[FOXO1](FOXO1)|Tier 2 GE[@dunsCharacterizationDLBCLPMBL2021], FE[@trinhAnalysisFOXO1Mutations]|[Duns et al](papers/dunsCharacterizationDLBCLPMBL2021)|[@morinFrequentMutationHistonemodifying2011; @schmitzBurkittLymphomaPathogenesis2012]|| |
| 120 | 97 | |[GCSAM](GCSAM)|Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019]|[Mottok et al](papers/mottokIntegrativeGenomicAnalysis2019)||| |
| 121 | 98 | |[GPR126](GPR126)|Tier 2 GE[@wenigerMutationsTumorSuppressor2006]|[Weniger et al](papers/wenigerMutationsTumorSuppressor2006)||| |
| 122 | 99 | |[HECW2](HECW2)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)||| |
| 123 | 100 | |[HELLS](HELLS)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)||| |
| 101 | +|[HIST1H1C](HIST1H1C)|Tier 2 GE, aSHM||[@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]|| |
|
| 102 | +|[HIST1H1D](HIST1H1D)|Tier 2 GE, aSHM||[@jalladesExomeSequencingIdentifies2017; @krysiakRecurrentSomaticMutations2017; @morinMutationalStructuralAnalysis2013]|| |
|
| 124 | 103 | |[HIST1H2BC](HIST1H2BC)|Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019], aSHM|[Mottok et al](papers/mottokIntegrativeGenomicAnalysis2019)|[@krysiakRecurrentSomaticMutations2017; @lohrDiscoveryPrioritizationSomatic2012]|| |
| 125 | 104 | |[HIST1H3B](HIST1H3B)|Tier 2 GE[@reichelFlowSortingExome2015], aSHM|[Reichel et al](papers/reichelFlowSortingExome2015)|[@lohrDiscoveryPrioritizationSomatic2012]|| |
| 126 | 105 | |[HIST1H4C](HIST1H4C)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)||| |
| ... | ... | @@ -135,7 +114,7 @@ link-citations: true |
| 135 | 114 | |[IL1RAPL2](IL1RAPL2)|Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019]|[Mottok et al](papers/mottokIntegrativeGenomicAnalysis2019)||| |
| 136 | 115 | |[IRF2BP2](IRF2BP2)|Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019]|[Mottok et al](papers/mottokIntegrativeGenomicAnalysis2019)||| |
| 137 | 116 | |[IRF4](IRF4)|Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019], aSHM|[Mottok et al](papers/mottokIntegrativeGenomicAnalysis2019)|[@drevalGeneticSubdivisionsFollicular2023; @morinFrequentMutationHistonemodifying2011]|| |
| 138 | -|[ITGB2](ITGB2)|Tier 2 GE[@]|||| |
|
| 117 | +|[ITGB2](ITGB2)|Tier 2 GE|||| |
|
| 139 | 118 | |[ITPR3](ITPR3)|Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018]|[Tiacci et al](papers/tiacciPervasiveMutationsJAKSTAT2018)|[@loveGeneticLandscapeMutations2012]|| |
| 140 | 119 | |[JUNB](JUNB)|Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019]|[Mottok et al](papers/mottokIntegrativeGenomicAnalysis2019)|[@lohrDiscoveryPrioritizationSomatic2012]|| |
| 141 | 120 | |[KLF2](KLF2)|Tier 2 GE[@deschGenotypingCirculatingTumor2020], aSHM|[Desch et al](papers/deschGenotypingCirculatingTumor2020)|[@drevalGeneticSubdivisionsFollicular2023; @jalladesExomeSequencingIdentifies2017; @pasqualucciAnalysisCodingGenome2011]|| |
| ... | ... | @@ -152,31 +131,52 @@ link-citations: true |
| 152 | 131 | |[NCOR2](NCOR2)|Tier 2 GE[@sarkozyMutationalLandscapeGray2021]|[Sarkozy et al](papers/sarkozyMutationalLandscapeGray2021)|[@schmitzBurkittLymphomaPathogenesis2012; @spinaGeneticsNodalMarginal2016]|| |
| 153 | 132 | |[NEK1](NEK1)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)||| |
| 154 | 133 | |[NFKB2](NFKB2)|Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019]|[Mottok et al](papers/mottokIntegrativeGenomicAnalysis2019)|[@reddyGeneticFunctionalDrivers2017]|| |
| 155 | -|[NSD2](NSD2)|Tier 2 GE[@]||[@beaLandscapeSomaticMutations2013; @zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 134 | +|[NSD2](NSD2)|Tier 2 GE||[@beaLandscapeSomaticMutations2013; @zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 156 | 135 | |[NUP214](NUP214)|Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018]|[Tiacci et al](papers/tiacciPervasiveMutationsJAKSTAT2018)||| |
| 157 | 136 | |[OR13C2](OR13C2)|Tier 2 GE[@gomezUltraDeepSequencingReveals2023]|[Gomez et al](papers/gomezUltraDeepSequencingReveals2023)||| |
| 158 | -|[PCBP1](PCBP1)|Tier 2 GE[@]||[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 137 | +|[OSBPL10](OSBPL10)|Tier 2 GE, aSHM||[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 138 | +|[P2RY8](P2RY8)|Tier 2 GE, FE[@muppidiLossSignalingGa132014]||[@drevalGeneticSubdivisionsFollicular2023; @lohrDiscoveryPrioritizationSomatic2012; @muppidiLossSignalingGa132014]|| |
|
| 139 | +|[PCBP1](PCBP1)|Tier 2 GE||[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 159 | 140 | |[PCDH7](PCDH7)|Tier 2 GE[@]||[@zhangGeneticHeterogeneityDiffuse2013]|| |
| 141 | +|[PCLO](PCLO)|Tier 2 GE||[@lohrDiscoveryPrioritizationSomatic2012]|| |
|
| 142 | +|[PHIP](PHIP)|Tier 2 GE|||| |
|
| 143 | +|[PRKDC](PRKDC)|Tier 2 GE||[@hubschmannMutationalMechanismsShaping2021; @schmitzGeneticsPathogenesisDiffuse2018]|| |
|
| 160 | 144 | |[PRUNE2](PRUNE2)|Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018]|[Tiacci et al](papers/tiacciPervasiveMutationsJAKSTAT2018)||| |
| 145 | +|[PTPRD](PTPRD)|Tier 2 GE||[@drevalGeneticSubdivisionsFollicular2023; @spinaGeneticsNodalMarginal2016]|| |
|
| 161 | 146 | |[RANBP2](RANBP2)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)||| |
| 162 | 147 | |[RBM38](RBM38)|Tier 2 GE[@wienandGenomicAnalysesFlowsorted2019]|[Wienand et al](papers/wienandGenomicAnalysesFlowsorted2019)||| |
| 163 | 148 | |[RDH12](RDH12)|Tier 2 GE[@]|||| |
| 164 | 149 | |[RELN](RELN)|Tier 2 GE[@sarkozyMutationalLandscapeGray2021]|[Sarkozy et al](papers/sarkozyMutationalLandscapeGray2021)|[@zhangGeneticHeterogeneityDiffuse2013]|| |
| 165 | 150 | |[RFTN1](RFTN1)|Tier 2 GE[@dunsCharacterizationDLBCLPMBL2021], aSHM|[Duns et al](papers/dunsCharacterizationDLBCLPMBL2021)|[@arthurGenomewideDiscoverySomatic2018]|| |
| 166 | 151 | |[RGS1](RGS1)|Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019]|[Mottok et al](papers/mottokIntegrativeGenomicAnalysis2019)|[@zhangGeneticHeterogeneityDiffuse2013]|| |
| 152 | +|[RHOA](RHOA)|Tier 2 GE, FE[@ohayreInactivatingMutationsGNA132016]||[@richterRecurrentMutationID32012; @zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 153 | +|[S1PR2](S1PR2)|Tier 2 GE, FE[@muppidiLossSignalingGa132014], aSHM||[@drevalGeneticSubdivisionsFollicular2023; @morinFrequentMutationHistonemodifying2011; @muppidiLossSignalingGa132014]|| |
|
| 167 | 154 | |[SCN9A](SCN9A)|Tier 2 GE[@]|||| |
| 168 | 155 | |[SENP7](SENP7)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)||| |
| 169 | 156 | |[SETD5](SETD5)|Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018]|[Tiacci et al](papers/tiacciPervasiveMutationsJAKSTAT2018)|[@reddyGeneticFunctionalDrivers2017]|| |
| 170 | 157 | |[SETDB1](SETDB1)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)||| |
| 171 | 158 | |[SIAH2](SIAH2)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)|[@hubschmannMutationalMechanismsShaping2021]|| |
| 172 | -|[SMAD3](SMAD3)|Tier 2 GE[@]|||| |
|
| 159 | +|[SIN3A](SIN3A)|Tier 2 GE||[@chapuyMolecularSubtypesDiffuse2018; @grandeGenomewideDiscoverySomatic2019; @rossiCodingGenomeSplenic2012]|| |
|
| 160 | +|[SMAD3](SMAD3)|Tier 2 GE|||| |
|
| 161 | +|[SMARCA2](SMARCA2)|Tier 2 GE|||| |
|
| 162 | +|[SMARCA4](SMARCA4)|Tier 2 GE, FE[@fernandoFunctionalCharacterizationSMARCA42020]||[@krysiakRecurrentSomaticMutations2017; @nadeuGenomicEpigenomicInsights2020b; @reddyGeneticFunctionalDrivers2017; @richterRecurrentMutationID32012]|| |
|
| 163 | +|[STAT3](STAT3)|Tier 2 GE, FE[@huNovelMissenseM206K2013]||[@morinFrequentMutationHistonemodifying2011]|| |
|
| 173 | 164 | |[STAT5B](STAT5B)|Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018]|[Tiacci et al](papers/tiacciPervasiveMutationsJAKSTAT2018)|[@reddyGeneticFunctionalDrivers2017]|| |
| 174 | 165 | |[STRAP](STRAP)|Tier 2 GE[@]|||| |
| 166 | +|[TAP1](TAP1)|Tier 2 GE||[@schmitzGeneticsPathogenesisDiffuse2018]|| |
|
| 175 | 167 | |[TBC1D15](TBC1D15)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)||| |
| 168 | +|[TBL1XR1](TBL1XR1)|Tier 2 GE, FE[@venturuttiTBL1XR1MutationsDrive2020]||[@drevalGeneticSubdivisionsFollicular2023; @lohrDiscoveryPrioritizationSomatic2012; @rossiCodingGenomeSplenic2012]|| |
|
| 169 | +|[TCF3](TCF3)|Tier 2 GE||[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 170 | +|[TET3](TET3)|Tier 2 GE|||| |
|
| 176 | 171 | |[TICRR](TICRR)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)||| |
| 172 | +|[TMSB4X](TMSB4X)|Tier 2 GE, aSHM||[@drevalGeneticSubdivisionsFollicular2023; @reddyGeneticFunctionalDrivers2017]|| |
|
| 173 | +|[TNFRSF1B](TNFRSF1B)|Tier 2 GE|||| |
|
| 177 | 174 | |[TNIP1](TNIP1)|Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018]|[Tiacci et al](papers/tiacciPervasiveMutationsJAKSTAT2018)||| |
| 178 | 175 | |[TRIP11](TRIP11)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)|[@zhangGeneticHeterogeneityDiffuse2013]|| |
| 176 | +|[UBR5](UBR5)|Tier 2 GE||[@albuquerqueEnhancingKnowledgeDiscovery2017; @pararajalingamCodingNoncodingDrivers2020]|| |
|
| 177 | +|[UNC5C](UNC5C)|Tier 2 GE||[@lohrDiscoveryPrioritizationSomatic2012]|| |
|
| 179 | 178 | |[VMP1](VMP1)|Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019]|[Mottok et al](papers/mottokIntegrativeGenomicAnalysis2019)||| |
| 179 | +|[VPS13B](VPS13B)|Tier 2 GE|||| |
|
| 180 | 180 | |[WDR87](WDR87)|Tier 2 GE[@dunsCharacterizationDLBCLPMBL2021]|[Duns et al](papers/dunsCharacterizationDLBCLPMBL2021)||| |
| 181 | 181 | |[ZCCHC11](ZCCHC11)|Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018]|[Tiacci et al](papers/tiacciPervasiveMutationsJAKSTAT2018)||| |
| 182 | 182 | |[ZNF217](ZNF217)|Tier 2 GE[@reichelFlowSortingExome2015]|[Reichel et al](papers/reichelFlowSortingExome2015)|[@hubschmannMutationalMechanismsShaping2021]|| |